Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Work placement as a professional development programme for vocational teachers has been widely implemented. This dissertation provides insight into vocational teachers’ learning process in this programme within Chinese vocational education.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer

Many handwritten and illustrated archives contain a wealth of information, but are largely underexplored because they are complex and difficult for computers to decipher. The aim of this project is to develop a digital environment that resolves this challenge and connects heterogeneous archival content…

This dissertation investigates the grammar of Makhuwa-Enahara, a Bantu language spoken in the north of Mozambique. The information structure is an influential factor in this language, determining the word order and the use of special conjugations known as conjoint and disjoint verb forms.

Simona Demková, Assistant professor at the Europa Institute of Leiden University, publishes her book ‘Automated Decision-Making and Effective Remedies: The New Dynamics in the Protection of EU Fundamental Rights in the Area of Freedom, Security and Justice’.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

Doctoral Thesis

The debate in Europe about digital sovereignty, technological sovereignty, data sovereignty and strategic autonomy has been building over recent years at both the EU level and the level of individual Member States. The different concepts – and their diverse interpretations – cover the sovereignty concerns…

The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.

This book presents an archaeological overview of the presence and development of Egyptian material culture in the context of Augustan Rome.

The article 'Standardising care of the dying: An ethnographic analysis of the Liverpool Care Pathway in England and the Netherlands' by Erica Borgstrom and Natashe Lemos Dekker is published in Sociology of Health & Illness.

On 12 November 2019, Larissa Koupriuchina defended her thesis 'Judgmental Adjustments in Revenue Management'. The doctoral research was supervised by Prof. J.I. Van der Rest.

Since the late 1990s, Leiden University has been located in two cities: Leiden and The Hague. Leiden Law School is also involved in teaching and research at Campus The Hague.

In this article, Honorata Mazepus, assistant professor at the Institute of Security and Global Affairs, and Dimiter Toshkov, associate professor at the Institute of Public Administration, discuss whether the winner–loser gap extends beyond the political domain to subjective health and well-being as…

How does invasive hybridization affect threatened native species?

Double Bind. Public service professionals coping with contrasting demands. How do public service professionals align their PSM with contrasting demands set by the organizational and social contexts in which they work?

In the Leadership Lab (4 EC) you tackle a topical problem presented by one of our partner organisations and develop important leadership skills in practice.

How to stimulate novel research in science and innovation

An archaeological case-study of the Pointe des Châteaux, La Désirade and Les Îles de la Petite Terre micro-region, Guadeloupe, F.W.I.

How public service motivation and professionalism affect decision-making in dilemma situations. Individuals who work in the public sector see themselves confronted with conflicting values, contradictory demands, and the need to serve an at times difficult to define ‘public interest’.

The Hague Journal of Diplomacy is hosted by the Institute of Security and Global Affairs at Leiden University. Besides the journal, there are many other activities related to diplomacy.

This article investigates the sources of legitimacy in multistakeholderism as a major alternative approach to intergovernmental global governance.

On October 31st, Margarita Gulian succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Margarita on this great result.

Examining mediation and moderation.

This project aims to explore the environmental impact of early Roman expansion (4th/3rd century BC) through a program of dating and ecological sampling of traces of field systems (centuriations).

Cultural Anthropology and Development Sociology

Edited by linguists Jenny Audring (Leiden University) and Francesca Masini (University of Bologna), this is a unique handbook with a focus on morphology theories rather than morphological data. It covers a wide array of morphological theories, from traditional twentieth century models to current theoretical…

This dissertation aims at discussing the nature and the linguistic factors assumed responsible for speech intelligibility problems of Sudanese learners of English.

In the past years access to EU law has been significantly enhanced via services such as EUR-Lex. This development not only allows for easy retrieval of individual legal acts, but for collecting information about the evolution of EU law in the aggregate as well.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

This article explores levels and patterns of legitimacy beliefs with respect to multistakeholder global governance at ICANN. From a large and systematic evidence base, Jongen & Scholte have found that ICANN has strong legitimacy underpinnings among its staff and board, as well as quite uniformly moderate-to-high…

There are different ways to keep up with Leiden University news.

The Ager Venusinus Project studies the relatively small number of recognized colonial dwellings dated securely to the period of colonization (i.e. the 3rd century BC). With a special interest in the Black Gloss ceramic typochronology

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Source: PLoS ONE, Volume 10, Issue 3 (2015)

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

This thesis aims at contributing to our understanding of the semantic and prosodic properties of object foci in Greek, employing theoretical and experimental tools.

In the past years, the Faculty of Archaeology has started to require that researchers provide evidence of ethical review before starting some projects, for example when working with human participants or human remains. This is in line with what many academic journals have started to include in their…

At LUCL we study almost all aspects of a wide range of African languages. From phonology to anthropological linguistics, from theoretical syntax to urban youth languages, we study it all.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

The main question I want to answer is about the mutual influence between the cultural and settlements changes that occurred between the Bronze and the Early Iron Age in Margiana and the management of water resources.

This project aims to explore, in general, what explains civil servants’ attitudes and behavior, and, in particular, why some civil servants are more committed to professional norms and public service values – such as impartiality, equity, efficiency, and innovation – than others.

Essays in Honour of Olivier P. Nieuwenhuyse

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.