Study information

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

This project intends to provide the required knowledgebase for the design of novel mild intervention protocols to prevent fungal food spoilage.

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.

In secondary education, teacher collaboration is used to further teachers’ professional development. In her dissertation, Loes de Jong (PhD candidate at ICLON) examines how various collaborative initiatives stimulate teacher learning. Her thesis defence is on 20 May 2021.

Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…

As UN Youth Delegate on Sustainable Development, Leiden student Aoife Fleming is currently in Madrid for the UN Climate Change Conference COP25.

Iranian molecular plant biologist Salma Balazadeh started her career in Germany. Now she sets up a research group in Leiden to study stress in plants to secure global food supply. Her outlook on women in science in the context of the International Day for Women and Girls in Science, 11 February.

Leiden University and Leiden University Medical Center have joined the Netherlands Centre for One Health (NCOH), further strengthening the academic network in which such problems as antimicrobial resistance are studied.

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…

How can Staphylococcus aureus bacteria subvert the host immune system?

Why do some bacteria lose their protective cell wall under the influence of stress? Microbiologist Dennis Claessen of the Institute of Biology Leiden receives a Vici grant of 1.5 million euros from the Dutch Research Council (NWO) to investigate this paradoxical feature.

How can the emergence of primary justice systems be facilitated and furthered?

Knowledge of Muslim societies is essential to function in a globalised world and to fully understand our own Dutch society. Leiden researchers explore the languages, cultures, religions, legal systems and history of Muslim societies and in this way contribute to a centuries-old tradition.

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?

How do we know what a quantum computer is good for when it hasn't been built yet? That's what PhD candidate Casper Gyurik investigated by combining two terms you often hear: quantum computing and machine learning.

Due to technological and societal developments, we are being flooded with more information than our brains can process. How does this affect our decision-making, both as individuals and as a society? And can we learn to make better choices? This is what Lotte van Dillen will explore with her profess…

Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.

How do children learn to see the world through someone else’s perspective? Max van Duijn, assistant professor at the Leiden Institute of Advanced Computer Science (LIACS), receives 24,167 euros from the Elise Mathilde Foundation and the Leiden University Fund (LUF). With this grant he will set up a…

For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…

The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.

Proteins organize themselves around our body cells through a self-induced force. They indent the cell membrane, which makes them roll towards each other. This discovery provides new insights into processes like nutritional uptake and brain signaling, as well as into such diseases as Alzheimer’s. Publication…

Disruption to the gut flora can affect your mental health. How could this knowledge be used to prevent stress-related disorders? This is what psychologist Laura Steenbergen will investigate with the aid of a project grant from the Leiden University Fund (LUF) and the Gratama Foundation.

Man is nature's mind-reading champion: we are better able than any other living beings to empathise with others. This comes in part from our story-telling culture, according to Max van Duijn. PhD defence 20 April.

Predicting whether someone will fall ill and which treatment will benefit them most: that is the aim of the techniques that Professor of Analytical Biosciences Thomas Hankemeier and his research group are developing at Leiden University. In order to scale up and further develop this technology, he works…

Leiden researchers found a way to measure the tiny forces exerted by pericytes, one of the most elusive, hard to research cell types, which occur in tiny blood vessels. Building on this fundamental science, researchers may eventually find treatments for medical conditions like ischaemia.

The channel through which two cell components exchange material appears to form at the edge of their contact surface, and not in the middle. This was discovered by the Leiden physical chemists Jelger Risselada and Edgar Blokhuis together with researchers from the University of Lausanne in Switzerland.…

Organ transplantation is often subject to ethical, economic and political discussions. In the Honours Class Organ Transplantation, students take part in these discussions to get a better understanding of the many different views on transplantation.

Some people are more sensitive to depression than others. But why is that the case? Clinical psychologist Niki Antypa studied how vulnerability to depression is influenced by cognition. She also found a first careful indication that a treatment with omega-3 fatty acids might provide a solution.

From painful joints to intense fatigue: a third of rheumatism patients suffer serious effects from this chronic condition and rely long-term on medication. Leiden psychologists are to receive a subsidy from the Netherlands Arthritis Foundation to investigate whether placebo techniques can help patients…

Boys with autism are more prone to develop physical complaints, depression and aggressive behaviour. Psychologists at Leiden University have discovered that this is mainly related to rumination. Publication in the Journal of Autism and Developmental Disorders.

Five projects with a lead applicant from Leiden will receive an Open Science Fund grant from the Dutch Research Council (NWO).

Music from a compostable cello, photographs and scents of fungi and a woven tapestry. With her upcoming multimedia project Super Organism, visual artist Suzette Bousema enables people to experience the underground fungal network with all their senses. Environmental scientist Nadia Soudzilovskaia and…

Ineke van der Ham has been appointed professor of Technological Innovations in Neuropsychology on 1 January. She researches how virtual reality and games help people navigate better. And this matters, as good navigation skills are about more than coming home safely.

Different groups of hominins probably learned from one another much earlier than was previously thought, and that knowledge was also distributed much further. A study by archaeologists at Leiden University on the use of fire shows that 400,000 years ago knowledge and skills must already have been exchanged…

The Veni grant is awarded annually by NWO (Netherlands Organisation for Scientific Research). This year, multiple researchers from Leiden University and 2 researchers who will soon be working at the university will receive a Veni grant from the NWO. Thanks to this grant, which can amount to up to 320,000…

Leiden social and organisational psychologist Carsten de Dreu has been awarded a Spinoza Prize, the top science prize in the Netherlands. We talked to him about his passion for group processes, Leiden University and his dreams for the future. ‘A Spinoza opens up a world of possibilities.'

Life returned to something resembling normal after Covid but other crises soon took its place. These great challenges are also being felt at the University and our researchers are working on solutions. The nitrogen crisis, problems with young people’s services and an increasingly urgent climate crisis:…

As the year draws to a close, many music lovers are looking forward to the Top 2000. How high is their favourite song and who is number one? But the list is often very predictable and the same songs are always in the top 10. According to neuropsychologist and associate professor Rebecca Schaefer, it’s…

Eye contact between parents and children improves their mood and increases feelings of connectedness on both sides; but not in the case of depressed adolescents, Mirjam Wever discovered. Where the parent-child bond has been disrupted, it can be strengthened not only with therapy for the child but also…

Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…

From the effects of hormone fluctuations in women via the interior structure of giant planets to the prehistory of the languages: six Leiden researchers have been awarded a Consolidator Grant by the European Research Council.

Mandrills keep track of how many days have passed to be the first to gather the food. This is shown by a team of researchers from the University of Amsterdam, Leiden University and ARTIS Amsterdam Royal Zoo. The team discovered that mandrills have the cognitive skills to learn time intervals of several…

Extremely painful chronic cluster headaches – sometimes referred to as ‘suicide headaches’ – can be prevented by stimulating the occipital nerve in the back of the head, according to research conducted by Professor Emeritus of Neurology Michel Ferrari from Leiden University Medical Center (LUMC). The…

From research on stellar winds to sign language: an impressive seven researchers from Leiden University will receive a prestigious Vici grant from the Dutch Research Council (NWO).