Symposium on the extraordinary excavations at Middenbeemster

Chemist Sander van Kasteren aims to accurately map how our immune system responds to vaccines, particularly those aimed at curing diseases like cancer and chronic viral infections. The goal is to use this knowledge to improve vaccine design. An ERC Consolidation Grant will provide him with the funding…

A global biological study has provided the most direct evidence to date that humans, and specifically cities, are the drivers of evolutionary change on Earth. Leiden University, Naturalis and the Municipality of Leiden worked on and helped fund the study.

The ‘Stans Prize 2018' (for the best thesis, report or article produced by a CML student) has been awarded to Louie Krol. Other CML prizes were awarded to Sebastiaan Deetman and Joris Timmermans.

Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.

Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'

An international partnership of brain researchers from 35 research centres - from the US to China - including the Leiden Institute for Brain and Cognition (LIBC), has collected resting-state functional MRI data from more than 1400 healthy volunteers and put the information online so that it is available…

The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…

Coen van Hasselt’s pharmacology group collaborated on a study recently published in the renowned Lancet Infectious Diseases. The international team mapped the antibiotic treatment of the life-threatening inflammatory reaction sepsis in newborn babies. They did this for low- and middle-income countries,…

The first Leiden Science Family Day on Saturday 6 October was a great success. During the ‘Weekend of Science’ more than 700 visitors, including 350 children, visited the Faculty of Science. With a program full of experiments, lectures, guided tours and demonstrations, visitors were given a glimpse…

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

We are pleased to announce that on the 30th of September Dr. Andrea Waters-Rist from the Faculty of Archaeology of Leiden University (The Netherlands) will be launching a Massive Open Online Course (MOOC) all about human osteoarchaeology!

New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

The staff of the Leiden University Medical Center are doing all they can to help as many corona patients as possible. They are also making regular media appearances to discuss the disease. Below are a few examples.

After 41 years, Meindert Danhof, Professor of Pharmacology, is leaving the Leiden Academic Centre for Drug Research on 31 March. A symposium in his honour, prior to his farewell lecture, will show what has been achieved in this period. Danhof takes a look back on his career.

David van Bodegom, Professor of Vitality in an Ageing Population, will give his inaugural lecture on 11 November, also titled Vitality in an Ageing Population. According to Van Bodegom the key to healthy ageing is the lived environment. In the fight against lifestyle-related conditions, he therefore…

Proteins organize themselves around our body cells through a self-induced force. They indent the cell membrane, which makes them roll towards each other. This discovery provides new insights into processes like nutritional uptake and brain signaling, as well as into such diseases as Alzheimer’s. Publication…

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…

Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…

A new health programme will reward patients with - or at risk of developing - cardio-vascular diseases for keeping to a healthy lifestyle. A research group including psychologist Andrea Evers has been awarded 2.5 million euros by the Dutch Heart Foundation and the Ministry of Public Health, Welfare…

Leiden Physics Poster

Too expensive groceries, diseases suddenly breaking out: from the sixteenth to the nineteenth century, hundreds of people documented the world around them in chronicles. A significant number of these texts have been digitised in recent years. Professor of Early Modern Dutch History and project leader…

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…

The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…

Seven Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Scientific Research (NWO).

The number of women in the Netherlands dying before, during or after childbirth has halved.

Publication by: Anouk Wezel, Sabine Welten, Wida Razawy, Max Lagraauw, Margreet de Vries, Eveline Goossens, Martin Boonstra, Jaap Hamming, Ekambar Kandimalla, Johan Kuiper, Paul Quax, Yaël Nossent and Ilze Bot. Annals of Surgery. 2015;262:841-848.

Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…

On 2 November, nine professors were simultaneously inaugurated as ‘Medical Delta Professor’ at Leiden University, LUMC, Delft University of Technology, Erasmus University and Erasmus MC. With an appointment at a minimum of two of these five academic institutions, they combine technology and healthcare…

To give a better idea of the research at Leiden University, a new website has been launched that lists the University’s institutes together with the disciplines that they cover. But the institutes also work together intensively.

In a world where bacteria are increasingly resistant to antibiotics, Emma van Groesen set out to find a solution. This month she obtained her PhD, after four years of research into new variants of the antibiotic vancomycin. With success.

Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.

Dialysis patients experience a range of physical and mental symptoms that interact and influence each otherIn her doctoral research, psychologist Judith Tommel wanted to find the optimum approach to help these dialysis patients improve their quality of life. ‘We need to make sure we avoid excluding…

Sometimes student life merges rather smoothly into a working adult life. This is the case for Boris Kowalski. At International Studies, he chose Russian as his language and Eurasia as his region of specialisation, he obtained his Master’s degree at Oxford in Russian and Eurasian studies, ended up in…

Social relationships of students are important. Especially for students with problem behavior. How can a teacher support students in their social relationships via their own interactions with students? A lot, as is shown by a meta-analyses of Hinke Endedijk. She assessed almost 300 studies about teacher-student…

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

On Friday 8 February 2019, we were honored by a visit of Ms. Anna Batalla, Human Rights Officer at the Petitions and Inquiries Section of the Office of the High Commissioner for Human Rights - United Nations, who gave a lecture on bringing a case to the Committee on the Rights of the Child and on the…

Schrödinger's cat is famously dead and alive, hidden in its closed box. As soon as one opens the box up to peek inside, the cat suddenly turns dead or alive. This is the 'measurement problem', that has stumped physicists for almost a century now. PhD student Tom van der Reep dared to look for a way…

Pitching competition

Nanotechnology has pervaded numerous industrial sectors over the past decades. Although many of us may not be aware of it, nanomaterials are now embedded within many of the the products we use in our daily lives. The agricultural sector might be next in line. Leiden environmental scientists Tom Nederstigt…

Research on the Greek and Roman times often focuses on important leaders, writers or politicians. However, Patricia Kret is more interested in the normal people living in these times. Her research focuses on amulets which were often used, for example to cure diseases. Why did people believe so strongly…

Criticism from doctors in the Netherlands about the policy to combat coronavirus is becoming louder. A letter raising their concerns was signed by one thousand doctors. It calls for a new debate on the current measures to deal with the crisis which were recently tightened. Supporters of the letter believe…

Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional or toxic. These misfolded proteins are then unfolded and subsequently refolded…

Aleydis Nissen published a feature article on the South Korean electronics industry in Eos magazine. The Pascal Decroos Fund sponsored this article.

Dimiter Toshkov, Associate Professor, Brendan Carroll, Assistant Professor, and Kutsal Yesilkagit, Professor International Governance, of Leiden University, wrote an article for the Washington Post about the European governmenets that acted quickly in times of a pandemic. And these governments are…

Recently, the PhD thesis of Lolu Danso Eweje appeared entitled ’Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin’.