Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional or toxic. These misfolded proteins are then unfolded and subsequently refolded…

Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.

On Monday 21 September Annemarie Meijer, Professor of Immunobiology, presented her inaugural lecture on immunobiology and infectious disease.

Corneal transplantation is one of the most common human organ transplantations worldwide. Although the 1-year survival rate is as high as 90%, more than half of transplantation patients suffer various types of corneal rejection, such as epithelial rejection, chronic stromal rejection, and endothelial…

ULLA, the European University Consortium for Pharmaceutical Sciences, is welcoming our tenth member: the School of Pharmaceutical Sciences of the University of Geneva. The School, which is heading the Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO) representing several academic institutions…

In June 2016, Janine Geerling and Marjo de Graauw were awarded a LUF-grant of €10.000 to design a digital laboratory support tool for the 2nd year BFW practical course on biochemistry (BC2p). With the help of a team of student assistants, Janine and Marjo managed to design a BFW LabBuddy tool that allows…

How can AI shape future wearables for population dynamics? This question made the underlying theme of the 8th Wearables in Practice Symposium, which took place on the 14th of October in Leiden.

Wednesday 18 January 2017, a university-wide meeting was organized on the upcoming alterations with regard to the role and tasks of Study Program Committees (Opleidingscommissies; OCs) within Leiden University.

Quincy Promes has been arrested in Dubai at the request of the Netherlands Public Prosecution Service. The Dutch judicial authorities now want Dubai to extradite Promes. But how does that work? Professor Jannemieke Ouwerkerk explains on ‘RTL Nieuws’.

Security in the broadest sense of the word was the key focus in the Interfaculty Conference on 4 April in Leiden. With almost 200 attendees and such well-known speakers as Dick Schoof, Pieter van Vollenhoven and Ad Verbrugge, the first conference was a success.

New research has confirmed that the Dutch military used systematic, extreme violence against Indonesians. In his book Soldaat in Indonesië (Soldier in Indonesia), to be released at the end of October, historian Gert Oostindie draws the same conclusions using different sources. He presents new findings…

There is a real chance of war closer to home, political and military leaders in Europe have warned. What does Frans Osinga, Professor of War Studies, think about the threat and what we should do?

Leiden University has had a turbulent week. There have been protests inside and outside our buildings that have evoked reactions, and students and staff have felt unsafe. We want with this message to look back at the past week and look forward to the future. What happened and how do we now want to move…

Intelligence and National Security is the new specialisation in MSc Crisis and Security Management (CSM). It will start next September 2021. Do you want to know more about this track?

Menzo Havenga, CEO of Batavia Biosciences on the Leiden Bio Science Park (LBSP), has a favourite hobbyhorse: the Clinical Development Board. The aim of this board is to make sure that high-impact research results in high-value products that will benefit patients.

Alireza Mashaghi and his research team have created a new framework to understand shapes of proteins and DNA. With this framework, many diseases can be understood better.

Since 2008 every half a year an SBB student starts with an internship for Merck Serono Ventures in Geneva. Head of the company Roel Bulthuis selects and works with the SBB interns and shares his experiences as an employer. He is very pleased.

How is it that some covid-19 patients are affected much worse than others? Can we predict beforehand which of them will develop critical symptoms Professor Thomas Hankemeier, together with a diverse consortium of universities, academic hospitals and industrial partners, is looking for the answers to…

While tens of thousands of visitors dance to deafening music, a team of Leiden psychologists are trying to collect data for their research at Lowlands. How do festivalgoers experience a virtual trip? And what role do factors such as too little sleep and whether they have experience with psychedelics…

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

Alireza Mashaghi from the Leiden Academic Centre for Drug Research (LACDR) will use state-of-the-art technology to investigate proteins that play a role in muscular dystrophy. His goal is to provide new insights for designing novel therapeutic strategies in the future. To accomplish this, Mashaghi receives…

A team of researchers has managed to recreate the most natural skin cream in existence. Using the DUBBLE beamline (Dutch Belgian Beamline) at the European Synchrotron Radiation produced on the basis of the information identified, has the same properties as vernix caseosa. This cream may have a therapeutic…

Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…

Researchers at Leiden University and TU Delft have combined two techniques that are used to measure the structure of biomolecules, creating a method that is ten times more sensitive.

Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.

Predicting whether someone will fall ill and which treatment will benefit them most: that is the aim of the techniques that Professor of Analytical Biosciences Thomas Hankemeier and his research group are developing at Leiden University. In order to scale up and further develop this technology, he works…

The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…

The death of his grandfather in 1988 motivates Changsheng Wu to become a scientist. In 2016, he is awarded the C.J. Kok Jury Award for his thesis on novel antibiotics. Two years later, he will become a Professor at Shangdong University, at the age of 30 years.

Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…

In the Netherlands, euthanasia has no longer been a criminal offence since 2002. The practice is governed by very strict conditions. Nonetheless, the legal issues surrounding it are still the focus of heated discussion, according to Leiden professors. They are discussing the issue on 18 March during…

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

Earning some quick money by drug trafficking, committing an act of violence or almost collapsing under performance pressure. In the four-part NeurolabNL Young vodcast young people talk openly with neuroscientists about high-risk behaviour and performance pressure. How did they find their way back?

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column

Eight young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This will allow them to conduct research at a top institute or university abroad.

Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…

Armed with sunglasses, a thick layer of sunscreen and several bottles of water, over 3,300 students have arrived in Leiden for their introduction week. The start of the 55th EL CID happened to be on the hottest day of the year.

This year, two Leiden master students will be awarded a KNMP Student Award. Both Wisse van Os and Jip Linthorst will receive 1,000 euros from the Royal Dutch Pharmacists Association (KNMP) as a reward for their excellent study results, motivation and commitment.

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

Imparting students with a critical attitude and cross-curricular skills. That is what Rawi Ramautar wants to strive for as the new programme director (OD) of the bachelor of Bio-Pharmaceutical Sciences. 'A programme director has to create a programme of which students say: I find it challenging and…

Seven Leiden researchers have each been awarded a Vici grant by the Netherlands Organisation for Scientific Research (NWO). This will enable them to form a research group and develop their own innovative line of research.

How can parents avoid passing on stress and mental health problems to their children? Professor of Stress-Related Psychopathology Bernet Elzinga develops simple interventions to help both parents and young people. For her research, she has been awarded the Spinoza Prize, the highest academic honour…

Tiny self-propelling spheres, measuring only micrometers, move faster over a hydrophobic silicone surface than they do over hydrophilic glass. 'Almost nobody had realised that the substrate matters', says Stefania Ketzetzi, the researcher who discovered the effect, researched it and explained it. She…

Joost van den Vondel is considered to be the greatest Dutch poet and playwright of his time, but he certainly wasn’t the most popular. The 17th- and 18th-century public preferred to watch ‘Spanish theatre’. University lecturer Olga van Marion has written a book about this, together with Frans Blom (University…

With a large majority of votes, drug researcher Alireza Mashaghi Tabari was chosen Discoverer of the Year 2017 of the Faculty of Science. This was announced by Rector Carel Stolker during the faculty’s New Year's reception on 9 January. Computer scientist Kristian Rietveld became Teacher of the Year…

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Light makes us flourish – in this respect we humans are just like a rose or an azalea. Light can also be used to treat people who are ill. In Leiden, Sylvestre Bonnet and Esther Habers are working – each in their own discipline – on new applications of light in a clinical context.

Advanced microscopy to understand life and fight disease: that’s the goal of the new NL-BioImaging network that will develop and integrate state-of-the-art microscopy technologies and services. Researchers from all Dutch universities, including Leiden University and the Leiden University Medical Centre,…

The Dutch National Research Agenda announced today that it will provide 17 research projects with a total of 61 million euros in funding. Researchers from Leiden University or the Leiden University Medical Center are involved in five of the projects. All of the projects are interdisciplinary partnerships…

In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…