Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

On Wednesday 31 August 2022, the graduation ceremony of the BSc Security Studies took place. The ceremony was opened by programme director Daan Weggemans.

Following periods of oppression and widespread violations of human rights, there is often a need for transitional vetting – a sort of ‘cleansing’ of the civil service. Where does this need come from? There are many answers to this question. But vetting, among other things, can contribute to recovering…

It may well be possible to remove nitrate from polluted groundwater and at the same time produce ammonia in a sustainable way, according to PhD candidate Phebe van Langevelde and Professor Marc Koper of the Leiden Institute of Chemistry in Joule on 26 January. Together with a German colleague, they…

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

Anne Marieke van der Wal-Rémy, assistant professor of African History and International Studies, has received a Comenius Teaching Fellow grant of 50,000 euros. She intends to use the grant to set up an online archive of digital primary sources, together with her students. Van der Wal-Rémy: ‘ “Once on…

Leiden University is home to over a hundred specialists studying the Middle Ages and the Early Modern period. From 2017-2018 onwards, they will join forces to offer two new options for specialisation within existing MA programmes: Medieval Studies and Early Modern Studies.

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

The rise of extremism in Europe has increased polarisation. The EU-funded DRIVE project, led by Tahir Abbas, Professor of Radicalisation Studies from Leiden University’s Institute of Security and Global Affairs, explores how social, structural, and individual factors contribute to radicalisation, offering…

Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?

Do you want to promote the interests of students or staff? If you do, put yourself forward as a candidate for the University Council or the Faculty Council between 5 and 8 April. Two council members, PhD candidate Elisabeth Kerr and Law student Mante Kaaks, tell us about their experiences.

The tree-year bachelor's programme in Archaeology is a many-sided programme in which you study societies, cultures, and human behaviour from the past, aiming to reconstruct and revive them. Dive into the development of human societies all over the world, from the Americas to the Middle East, from the…

The Royal Netherlands Academy of Arts and Sciences has elected five Leiden professors from different disciplines as new members. One of them is Judi Mesman, Dean of LUC

What’s it like to study a certain programme within the Faculty of Humanities at Leiden University? These prospective students found out during the Experience Day on Friday 6 April. They had a taste of the faculty’s atmosphere and discovered what study programmes are actually about.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

Ragazzi, ‘Suspect community or suspect category?‘, Journal of Ethnic and Migration Studies

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: H.M. Cuppen, S. Ioppolo

This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.

PhD candidate Jiangnan Ding explores how you can design a thick slab of rubber in a way that it might act as a mechanical computer bit. This so-called mechanical metamaterial is pushed in a specific way to change its shape. ‘With a very simple material, we might be able to do simple calculations in…

On the Master’s Open Day on 15 February Liza Vromen from Harlem arrives in Leiden to investigate the pre-master’s programme Psychology. As a matter of fact she will look beyond that programme for a master’s specialisation which fits her personal interest.

According to Russian propaganda Ukrainians are Nazis and people from the West are Satanists. Egbert Fortuin thinks we should take this propaganda seriously.

It gives us great pleasure to report that the search for a University Lecturer in Christianity in the Modern World has resulted in the appointment of Corey Williams, starting January 2015.

More than a hundred people took part in the conference on Studying with a Disability on 20 April. Dozens of students shared their experiences. 'I would rather you ask me the same question a hundred times than that you decide on my behalf.'

How can we quantify the density of species within a community through environmental DNA concentrations?

Through a range of case studies spanning the post-Cold War period in Iraq, Moldova and Serbia, this book studies asymmetric conflicts where warring sides exhibit vast power differentials.

The Board of Governors of Leiden University has confirmed the appointment of Professor André Gerrits (Institute for History, currently in the field of Russian Politics and History) to the field of International Studies and Global Politics, commencing October 1st 2015.

This doctoral thesis comprises four studies on the content and structure of physics teachers’ belief systems about teaching and learning physics in secondary education in the Netherlands.

In an (Dutch) interview with the regional Leiden newspaper “Leidsch Dagblad”, Ruben Huele and Ester van der Voet talk about the recently started project PUMA (Prospecting the Urban Mines of Amsterdam).

Conference, Workshop

Over eighty percent of all Dutch requests to send asylum seekers back to the country where they should have requested asylum lead to nothing. This is shown by recent figures that Dutch broadcasting corporation NOS requested from the Ministry of Justice. That percentage applies to 2020, the year for…

The urban graveyard presents several studies in which the results of older archaeological and osteoarchaeological research are compared to more recent excavation data from several Dutch, Belgian and Danish cities and towns.

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

The starting hypothesis of the project is that secrecy is not always inimical to democratic governance as conventional wisdom has it.

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This project aims to investigate the underlying (neurocognitive) linguistic processes of ellipsis resolution, particularly gapping.

This collection of seventeen essays takes its inspiration from the scholarly achievements of the Dutch historian Jan Lucassen. They reflect a central theme in his research: the history of labor.

Including modelling as part of software development appears to have various benefits.

On the 24th of September, Louise S. Friis successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Louise on this achievement!

The Security Studies bachelor's programme has received a bronze medal in EW Best Studies 2023. Every year, EW Best Studies selects the top programmes in Dutch higher education.