3,856 search results for “role work in role environmental” in the Public website
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Central role of Claudin-1 in lesional but not in non-lesional atopic dermatitis
Source: Journal of Investigative Dermatology, Volume 134, pp. S44-S44 (2014) ISBN: 0022-202X
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Cutaneous barrier dysfunction in atopic eczema: the role of stratum corneum lipids
Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Role of near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
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Positioning of current Environmental tools & an outlook to the future
Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.
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Designing 'context-specific' regional innovation policy: a study on the role of regional government in six European regions
Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…
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Ecological functions and environmental fate of exopolymers of Acidobacteria
Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.
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The role of AGC3 kinases and calmodulins in plant growth responses to abiotic signals
Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa
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large-scale implementation of BioSolarCells, Early stage assessment of environmental value propositions
What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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A family affair? Exploratory insights into the role of family members of those who joined jihadist groups
Since 2012, thousands of individuals have traveled from Western countries to join jihadist groups in Syria and Iraq. While much has been written about these individuals, only sparse attention has been paid to the social environment of these jihadist travelers and, more specific, the role of family members…
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.
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The mystical kiss of the mouth. The role of images and imagery in medieval spirituality (1100-1500)
How can the importance of the image in late medieval spirituality be understood in the context of the love mysticism inspired by the imagery of the Song of Songs?
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Congruence between voters and parties: The role of party‐level issue salience
The level of congruence between parties and their voters can vary greatly from one policy issue to another, which raises questions regarding the effectiveness of political representation. We seek to explain variation in party–voter congruence across issues and parties.
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Democratic Secrecy: A Philosophical Study of the Role of Secrecy in Democratic Governance
The starting hypothesis of the project is that secrecy is not always inimical to democratic governance as conventional wisdom has it.
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Design for the Future: Wicked Environmental Problems in Sustainability and Health
How do we approach education that facilitates creative confidence for students that leads to innovative solutions to society’s present day and future sustainability challenges? This education research project tackles a sustainability dilemma faced by households in everyday life viz.
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Rosanne van der Voet
Faculty of Humanities
r.van.der.voet@hum.leidenuniv.nl | +31 70 800 9500
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Analogy, Technical Reason, and Living Beings: The Role of Analogy in Representing Kant's Concept of Naturzweck
This dissertation concerns the role of analogy in Kant’s “Critique of the Teleological Power of Judgment”, especially the role of analogy for the formation of the concept of a natural end (Naturzweck). A ‘natural end’ is a ‘regulative concept’ of the reflective power of judgment, that is, a heuristic…
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Neurobiological and Environmental Determinants of Parenting and Child Development
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Polar auxin transport: translating environmental signals into plant developmental responses
1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects
On 20 October 2021 Michael Ramsden defended the thesis 'The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects'. The doctoral research was supervised by Prof. N.M. Blokker.
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More than a digital system: how AI is changing the role of bureaucrats in different organizational contexts
In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).
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Kaushar Kagzi
Science
k.kagzi@cml.leidenuniv.nl | +31 71 527 2727
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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Dead or Alive? The role of personal characteristics and immediate situational factors in the outcome of serious violence
Why do certain incidents of serious violence end lethally whereas others do not? What role do personal characteristics of offenders and victims play and how do immediate situational factors influence outcomes?
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organizational learning orientations in the wake of a crisis and the role of public service motivation
This study explores public leaders’ organizational learning orientation in the wake of a crisis. More precisely, we study the association between public leaders’ public service motivation and their learning orientation (instrumental versus political).
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Why do citizens (not) support democratic innovations? The role of instrumental motivations in support for participatory budgeting
In recent years, the question why citizens (do not) support democratic innovations has attracted increasing academic attention. In this research note, Van Der Does & Kantorowicz for the first time empirically verify what drives citizens’ instrumental considerations in their evaluation of a DI.
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Role of epigenetics in long-term health effects of early life stress
Can epigenetic changes explain associations between early life stress and health outcomes?
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The Scandal of Cal: A Conversation about the Role of Academic Institutions in Historical Exploitation
Lecture, Global Questions Seminar
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the Water: Incineration at Sea and the Birth of a Transatlantic Environmental Movement
Dario Fazzi
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Avoiding conflict after the cyclone: Land rights and environmental displacement in Central Mozambique
This socio-legal research focuses on the impacts of environmental displacement on land rights and land-related conflict in Mozambique in the aftermath of cyclone Idai, and on the role of the legal framework in addressing these problems.
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The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law
On 23 juni 2019, Zygimantas Juska defended his thesis 'The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law'. The doctoral research was supervised by Prof. dr. T.R Ottervanger.
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Robert Verpoorte
Science
verpoort@chem.leidenuniv.nl | +31 71 527 4528
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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Searching for the concrete subject: On the epistemic role of lived-experience in Paul Natorp's critical epistemology
The following dissertation reconstructs Paul Natorp's philosophical psychology. It argues that psychology's main object is the lived experience of concrete subjects, understood as a transcendental structure of logical-reflexive conditions for the recognition, appropriation, and evaluation of objective…
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Getting to the Core of Crimmigration. Assessing the Role of Discretion in Managing Intra-Schengen Cross-Border Mobility
To what extent are there differences between countries in and outside the European Union and the Schengen area in the level of crimmigration, the merger between migration control and crime control, and to what extent can these differences be explained by the way in which state and non-state actors in…
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UNravelling the socioeconomic and environmental Impacts of Circularity in Latin America (UNICA)
A MSCA Global Fellowship that aims to explore the socioeconomic and environmental implications of a Latin America circularity transition, and its impact on the EU and global economy.
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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The role of hearing signers in the development of channel specific structures in sign languages of deaf communities
In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.
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Sjoerd Lopik in Mr. Online on environmental criminal law
Dutch online news platform Mr. Online interviewed external PhD student Sjoerd Lopik about the development of environmental criminal law in the Netherlands and about his experiences combining his job as a researcher with his work in the legal practice.
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival
On 19 December 2019, Reza Eftekhar defended his thesis 'The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival of the Localisation Theory'. The doctoral research was supervised by Prof. E. de Brabandere.