In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 158-158 (2015) ISBN: 0142-5463

PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

The Cognitive Psychology Unit has two main research lines, which focus on basic cognitive (neuro)science and applied cognitive psychology.

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

Promotor: S.M. Verduyn Lunel

The factors that dynamically sculpt the inter-regional correlation of brain patterns are poorly understood. Here, we test the hypothesis that they are shaped by the catecholaminergic neuromodulators norepinephrine and dopamine.

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

My PhD thesis investigates the ecological significance of resistance against drought-induced air bubble formation inside the water conduits of plants (embolism), and the plasticity and functional aspects of stem anatomical traits in woody and herbaceous species.

The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Psychologist Bernadet Klaassens initiated a large fMRI study on the effect of drugs on brain networks in aging and Alzheimer's disease. It generated a unique data set and insight into a new method to develop drugs for patients with Alzheimer's.

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

The Directorate-General Police, Sanctions, and Protection has initiated this research project in order to gain insight in the nature and, if possible, the extent of the developments with regards to the pluralization of policing functions in the Netherlands in support of future policies for the benefit…

Green infrastrucuture (GI) like urban farm and green roofs could provide many beneficial functions in cities. These include for example food production, flood prevention or increasing biodiversity. MultiGreen project aims at developing an integrated modelling tool to support…

During the course of drug discovery translational steps are made.

This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

This study explores regional variation in the use of utterance-final particles by analyzing spoken Taiwan Mandarin data recorded from spontaneous conversations.

The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

The aim of this thesis was to study the link between hearing loss, language skills, and social functioning in deaf and hard of hearing (DHH) children. Sufficient language skills are an essential prerequisite to develop appropriate communication skills, in order to join in conversations with others.…

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

Form and Function in Greek Grammar. Linguistic Contributions to the Study of Greek Literature is a new book, written by Albert Rijksbaron. Rijksbaron is internationally known as one of the leading scholars of the Ancient Greek language, whose work has exerted a strong and lasting influence on the scholarly…

The recently published book ‘Avian Cognition’ is the first multi-author book to provide a comprehensive treatment of the cognitive abilities of birds and how they compare to those of other animals. Carel ten Cate, professor of animal behavior at the Institute of Biology, and Susan D. Healy (StAndrews…

Psychoeducational Assessment, Intervention and Rehabilitation (PAIR) publishes high quality articles on theoretical and empirical research regarding psychological and psychoeducational assessment, intervention, and rehabilitation in all areas related to cognitive and socio-emotional development.

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

PhD defence

Fred Janssen is curious about how best to teach students and students to gain a good understanding of complex ‘swamp situations’. This is the subject of his inaugural lecture as Professor of Science Education at the ICLON and the Faculty of Science. Inaugural address 19 June 2017.

An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.