The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

On the 29th of June, Martin Kohlberger successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Martin on this achievement!

Investigating specific language and speech behaviour of people.

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.

Promotor: Prof.dr. T. Schmidt

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

The Mathematics and Algebra, Geometry and Number Theory specialisation programme consists of 120 European Credit Transfer System (EC) points and includes a research project (40 EC), advanced courses (min 60 EC) and electives (maximum 20 EC). 30 EC are to be taken from the Dutch national Mastermath p…

The Applied Mathematics Programme consists of 120 European Credit Transfer System (EC) points. The programme consists of advanced courses (min 60 EC), a research project (40 EC) and electives (max 20 EC).

The research specialisation offers you the opportunity to spend two full years on training in applied mathematics to become an independent scientist with a strong theoretical basis.

In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

Accurately recognising others’ emotions is a fundamental social skill, relevant for navigating the social world from early childhood. Children’s ability to do represents a milestone in their socioemotional development and is associated with a number of important psychosocial outcomes. Many individual…

This thesis presents a detailed description of the phonology, the tone system and the grammar of Liko, a Bantu language spoken by about 70,000 people in the northeastern part of the Democratic Republic of the Congo. It provides numerous examples.

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

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How does global change across time and space lead to convergence and loss of variation or increasing diversity and conflict?

The data-driven economy allows for the collection and processing of large amounts of data. Such data can be used to optimize profits by (dynamically) differentiating prices for different consumers.

Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…

The research that is united in the Liveable Planet programme, touches upon a wide range of aspects of human life. The goal is to deepen and expand the scope and to connect more researchers. The following case studies are examples of current research projects.

The unique geographic and temporal breadth of research at Leiden allows us to stimulate a shift from the classical Weberian mode of scholarly production that views historical development and modernization as emanating from Europe and the West to a multi-polar perspective that allows for more nuanced,…

This research examines the social, political, and cultural forces that structure people’s responses towards accented speech, and further uses the accent as a focal point to theorize the interrelation between language and body.

On 21 September 2022 Arfiansyah successfully defended a doctoral thesis and graduated.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Source: Mediators Inflamm (2014)

This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.

Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

Can we identify different degrees of economic integration, both within and between regions, on the basis of archaeological proxies?

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

On the 2nd of September Jiyan Qiao successfully defended a doctoral thesis and graduated.

In this article, Dimiter Toshkov investigates the determinants of COVID-19 vaccine hesitancy and refusal, focusing on Eastern, Southern and Western Europe.

How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

The master's specialisation Applied Mathematics at Leiden University focuses on both computational and fundamental aspects of analysis and probability. It’s also an ideal basis for a PhD degree. Applied Mathematics is an excellent choice if you have the aspiration to pursue a PhD degree

Madeleine O. Hosli & Jaroslaw Kantorowicz analyze EU states' foreign policy divergence at the UN General Debate, assessing if Lisbon Treaty reforms increased EU cohesion or if states maintain distinct positions.

The master’s programme Mathematics at Leiden University focuses on analysis, probability and statistics, number theory and (arithmetic) geometry. It offers five specialisations ranging from Applied Mathematics to Mathematics and Business Studies.

What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…

Investigating the emergence of complex societies in Chalcolithic Cyprus.

Making sensitive data reusable through synthetic data generation

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Urban, Food, Water, Biodiversity, Resources and Energy: these are the main research topics of the Institute of Environmental Sciences. We always strive to be a global leader in our field. And make a real impact with both our research programmes.

The aim of the research programme is to provide insight into the cognitive processes and brain mechanisms that underlie reading, arithmetic and learning in general.

This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.

Who were the main artists and producers who generated new forms of popular music? What was the music like that was produced by artists in particular urban settings? How were particular lifestyles articulated to identify new audiences and what does this reveal about the way popular music contributed…