On 1 October 2024, Dr Jiska Engelbert was appointed as professor by special appointment on the Ien Dales Chair ‘Government as an Employment Organisation’. Her focus is on leadership in digital transitions, digital innovations, and the transformation of public services, with particular attention to local…

The logo of Leiden University, with letters as small as a bacterium. Researchers from LUMC and the Institute of Biology have created the smallest logo of our university ever produced. It is a piece of fun with a serious real-world application: the new microscope with which the logo was made allows scientists…

In our lab, we investigate the physics and material properties of low-dimensional systems.

Three projects with Leiden researchers are to receive a subsidy from NWO for the construction or renovation of large-scale research facilities. They will be working on electron microscopy, an X-omics initiative and an X-ray telescope. The projects are part of the National Roadmap for Large-Scale Scientific…

On this page you can find the current vacancies at the Van der Molen research group.

The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

White clouds of ice-cold gas flowing across the floor. Magical, but be careful not to freeze your fingers off. We are of course talking about liquid nitrogen and helium. You may have seen the spectacular Freezing Physics science show by the student organisation Rino. But did you know that this commodity…

Speakers that have accepted to participate:

This dissertation derives from the development of tools for algorithmic composition which extract pitch materials from sound signals, analyzing them according to their timbral and harmonic properties, putting them into motion through diverse rhythmic and textural procedures.

On 21 March The Netherlands Centre for Electron Nanoscopy (NeCEN) hosted the Life Sciences Café. Around 60 people from neighbour companies from the Leiden BioScience Park visited the facility for cryo-electron microscopy to get a glimpse behind the scenes. Head of NeCEN Ludo Renault believes it was…

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

The High Troughput Microscopy Dutch Flagship Node that includes the Leiden Cell Observatory Screening platform is now officially ratified as a Euro-BioImaging (EuBI) Node Candidate

The master’s specialisation Research in Physics, Quantum Matter and Optics at Leiden University offers a thorough experience on the front line of physics research with a practical training of communicative and computer skills. The programme focuses on Condensed Matter problems, such as Molecular Electronics,…

Stacked layers of graphene can act like a mirror for beams of electrons. Physicists Daniël Geelen and colleagues discovered this using a new type of electron microscope. In an article in Physical Review Letters, they describe their results, which could lead to the development of optics for electron…

By detecting the tiny forces between a micrometer sized magnet and the spins of hydrogen nuclei, we can do MRI with a volume resolution that is approximately 12 orders of magnitude better than a conventional MRI.  

A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

PhD defence

PhD defence

Ariane Briegel has been appointed Professor in the fìeld of Ultrastructural Biology within the Faculty of Science at the Institute of Biology from the 1st of December 2015. Her expertise is in using electron cryotomography to study how microbes sense and respond to their environment.

An international team with researchers from Leiden revealed how a bacterium repurposed an internal system to control its movements. Movement control is very important in host invasion, which can lead to disease. Publication on 27 April in Nature Communications.

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology. They are staffed by scientists with vast experience in their field, ensuring that all researchers can count not only on the latest available technology…

Archaeometric analysis of glazed pottery assemblages from the Early Byzantine to the Early Modern periods in the Aegean.

Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

On 24 May 2022, the universities of Tokyo and Leiden organized a rotating chair named after Professor Hisashi Owada. The Owada Chair focused on the interaction between international law and international relations in an interdisciplinary perspective. Dominique Moïsi, a professor at Kings College London…

PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

As per 1st May 2019, Leiden University appointed Bram Klievink as professor of Public Administration with a focus on digitalization and public policy. The new chair has been established at the Institute of Public Administration of the Faculty of Governance and Global Affairs of Leiden University. Bram…

Developing computational algorithms for structural biology -A high resolution, three dimensional view of a molecule provides detailed information that help elucidate its function: by knowing the exact arrangement of atoms in a molecule, we can understand disease, develop drugs to combat them and improve…

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

The Kikkoman chair is a new chair in Leiden sponsored by the Kikkoman Foundation and the Association of Friends of Asiatic Art. The chair will address the intercultural dynamics of Asia and Europe.

A new executive board has been installed at NeCEN, a state-of-the art facility that offers the most advanced cryo-electron microscopes worldwide. The new board members are full of excitement: what are their ideas for the future of the facility?

Promotor: Prof.dr. E.J.J. Groenen

Freya Baetens, Professor of European Law, has been awarded a Chair by the Francqui Foundation in Belgium for the impact of her work on lawmaking and policymaking in Europe and beyond.

PhD defence

Aleydis Nissen published a feature article on the South Korean electronics industry in Eos magazine. The Pascal Decroos Fund sponsored this article.

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

This thesis investigated how microphones and loudspeakers could become musical instruments.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…