713 search results for “cancer drug discovery initiatief” in the Staff website
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Coen van HasseltScience
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Celebrating 40 Years of Bio-Pharmaceutical Sciences
During our special Fall symposium on November 28, we celebrated the 40th anniversary of Bio-Pharmaceutical Sciences. Organized in collaboration with our study association L.P.S.V. „Aesculapius”, the event brought together staff, students, and alumni for an afternoon focused on four decades of ‘Innovation…
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and Italian pharma company receive an EU grant to realise sustainable drug production
With a €1.5 million European grant, industrial ecologist Stefano Cucurachi will work on more sustainable production methods for the pharmaceutical industry. The Italian company Angelini Pharma intends to use the resulting knowledge to make its production process more sustainable.
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for effective application of a new revolutionary cholesterol lowering drug resides in a 30 year old Leiden Patent
‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…
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'There's nothing more we can do for you' - New publication on harmful communication in oncology
PhD student Janine Westendorp and her colleagues conducted literature research on what patients with cancer and their loved ones perceive as harmful communication from healthcare providers. The results were published in the journal Psycho-Oncology and are released as a poster to distribute to healthcare…
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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UMCs join forces to increase pandemic preparedness
Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
PhD defence
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Elizabeth (Liesbeth) de LangeScience
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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Mick van SchaickScience
m.van.schaick@lacdr.leidenuniv.nl | 071 5272727
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These were Leiden University’s interdisciplinary milestones of 2024
Connecting scientific fields, enhancing research and teaching, and providing innovative solutions to complex social issues: that is the idea behind interdisciplinary research. What did the university achieve in 2024? A small sample.
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Mathematics student Lars Pos wins Robbert Dijkgraaf Essay Prize: 'Discoveries find their application in the most unexpected places'
With his essay 'Why science?', mathematics prodigy Lars Pos (18) won the Robbert Dijkgraaf Essay Prize. Within the theme 'The fascinating workings of science', the bachelor student wrote a plea for the societal value of fundamental scientific research. 'Because you don’t know beforehand where we can…
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Bas ter BraakScience
s.j.ter.braak@lacdr.leidenuniv.nl | +31 71 527 2727
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Marcel SchaafScience
m.j.m.schaaf@biology.leidenuniv.nl | +31 71 527 4975
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Thomas HankemeierScience
hankemeier@lacdr.leidenuniv.nl | +31 71 527 4226
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Marije NiemeijerScience
m.c.niemeijer@lacdr.leidenuniv.nl | +31 71 527 6105
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This is the library you did not know you had been looking for
2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…
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Causal Discovery: Challenges and Opportunities
Lecture
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Connect & discover: data registration, deposition and discovery
Network meeting
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From droplets in the freezer to the inception of a potent new antibiotic
What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…
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Who are the winners of the Psychology Prizes of 2024?
Psychology teacher of the year is Evelien Broekhof. The Master Thesis Awards are for Yanna Naeije and Arian Memarpouri. Mirjam Wever wins the PhD Paper Prize; Jip Aarts wins the PhD Wild Card: Academic Citizenship. Congratulations!
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Discovery and characterization of new glucosylated metabolites
PhD defence
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Discovery of selective diacylglycerol lipase β inhibitors
PhD defence
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
PhD defence
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Training: alcohol and drug use among students
Training for staff members
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Training: alcohol- and drug use under students
Training for staff members
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‘Pharmacogenetics will become part of patient care’
Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’
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Selective cannabinoid CB2 receptor activation in Nature Communications
This March, Jara Bouma, Cas van der Horst and Laura Heitman from the Division of Drug Discovery and Safety and Laura de Paus, Richard van den Berg, Anthe Janssen and Mario van der Stelt from the LIC joined forces to determine how some drugs can specifically target the cannabinoid CB2 receptor (CB2R)…
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Review on “Anticancer opportunities at every stage of chemokine function” is featured on the cover of TIPS
Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…
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During the next pandemic, this mathematical model will speed up the search for treatment
Do you recall all those drugs that were hastily proposed as potential treatments for COVID-19? In the event of a future pandemic, the goal is to offer an effective treatment more quickly and efficiently. To achieve this, a team led by Coen van Hasselt is developing a platform that can speed up the process…
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Regulation of signal transduction pathways by hypoxia in breast cancer subtypes
PhD defence
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Pharma-NL application submitted to National Growth Fund
The Ministry of Health, Welfare and Sport (VWS) submitted Pharma-NL to the R&D program of the National Growth Fund, a 20 billion euro program of the Dutch government that intends to create long-term economic growth in The Netherlands.
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Proof of Concept grants for four Leiden researchers
Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
PhD defence
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Antibiotic Discovery: From mechanistic studies to target ID
PhD defence
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Four NWO Open Competition grants for Leiden researchers
Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.
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LACDR EMA Lunchtalk
On Friday the 29th of October, LACDR presented highlights of its research and teaching program during an online Lunchtime Talk session at the European Medicines Agency (EMA).
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Multifaceted Roles of Grainyhead-like Transcription Factor- 2 in Breast Cancer
PhD defence
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BRCA1-associated breast cancer: finding new weapons for an old villain
PhD defence
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
PhD defence
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Patient-derived models of breast cancer: A breakthrough story of the duct
PhD defence
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Cancer-induced somatic mutations in G protein-coupled receptors
PhD defence
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From data to discoveries: machine learning and optimization in space
Lecture
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ULLA workshop – summer school - courses
We are proud partner of the ULLA. It is the European University Consortium for Pharmaceutical Sciences in which LACDR participates for already 30 years. We have the honor to host the ULLA workshop in 2023 and the ULLA summer school in 2024.