Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

PhD defence

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

Finally we know for sure that there is a black hole at the centre of our own galaxy. Today, astronomers unveiled the first ever photo of Sagittarius A*, a super-massive object at the centre of the Milky Way. This picture could only be taken thanks to the cooperation of telescopes worldwide.

2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…

Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…

Cancer treatments often have an impact on people’s sexual health, but doctors and nurses do not discuss topics such as sexuality and intimacy with patients as a matter of course. This is what Esmée Krouwel, a physician-researcher at Leiden University Medical Center (LUMC), has discovered. With her research…

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

Oncode Investigator Mario van der Stelt and his colleagues have discovered a new potential drug that suppresses chemotherapy induced neuropathic pain.

The research project 'when patients don't want to know everything: guide and training for culturally sensitive information in palliative care' investigates how healthcare providers can offer inclusive palliative care.

Leiden PhD candidate Mona Shahab climbed Mount Everest two years ago to raise money for the education of disadvantaged children in Egypt. She made it to the top and posed there with the University flag. She recently presented the flag to Rector Carel Stolker.

Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…

Beads are among the oldest types of human artistic expression. Even so, the small ornaments have a bad status record regarding archaeological investigation. PhD candidate Mette Langbroek, usually at home studying early medieval beads, had the opportunity to work on a publication and exhibition on 5000…

Care robots, medical treatments, deepfakes and self-driving cars all with the aid of artificial intelligence (AI). The BrAInpower exhibition at Rijksmuseum Boerhaave shows spectacular applications of AI and explains how it can make such huge leaps. Bas Haring, Professor of Public Understanding of Science,…

An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

While health data is essential for scientific research, that data also needs to be protected. In her doctoral thesis, Irith Kist found a balance between protecting the individual and exchanging health data.

How would you convert Egyptian hieroglyphs into Latin script? And what is actually the correct translation of dishes on a Vietnamese menu? On Saturday 28 January, high school students from all over the Netherlands will come to Leiden to ponder a series of language-related puzzles. Their goal? To win…

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

Statistician Anja Rüten-Budde has won the C.J. Kok Jury Award 2020. Her PhD thesis resulted in an app which helps patients with soft tissue sarcoma and their doctors to make well-considered choices about the treatment. ‘Her work is interdisciplinary and directly relevant for society,’ the jury state…

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

Education

Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.

Leiden researchers Tazuko van Berkel (Greek and Latin Language and Culture) and Noel de Miranda (Tumour Immunology, LUMC) will join the KNAW’s Young Academy next year. They will be inducted on 22 March 2021.

An important question being asked, both in the academic world and in society, concerns the impact of our research and education. By providing a well-supported answer, we not only create a strong position for our research, we also increase our chances of success in applying for research grants and retaining…

An important question being asked, both in the academic world and in society, concerns the impact of our research and education. By providing a well-supported answer, we not only create a strong position for our research, we also increase our chances of success in applying for research grants and retaining…

Nienke van der Marel has been awarded the New Horizons Prize in physics for her pioneering research on planet formation. This prize is given to young, promising researchers in physics or mathematics. The astronomer and her colleagues found the first observational evidence for 'dust traps' in disks around…

Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

From an emergency fund for Ukrainian students to a golf tournament for cancer research at the LUMC: the Leiden University Fund (LUF) crowdfunding platform is full of fantastic projects that enrich the university. If you are looking for funding for your idea or special project, crowdfunding may just…

With Leiden2022 drawing nearer, LeidenGlobal is busy developing extra activities to demonstrate the knowledge that is present in Leiden and to create interaction with a wider audience. With this valorisation, the partnership between several cultural and academic institutions in Leiden matches the theme…

On Monday 26 February the terrible news reached us that our gifted former Egyptology student – and former student assistant at the Leids Papyrologisch Instituut – Juan Archidona Ramírez had succumbed to cancer.

Suzan Verberne has been appointed professor of Natural Language Processing at the Leiden Institute of Advanced Computer Science (LIACS) from 1 October. Verberne has been at LIACS since 2017 as group leader of the Text Mining and Retrieval group.

Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…

Leiden psychologists Janine Westendorp and Liesbeth van Vliet have investigated types of communication that seriously ill patients may experience as harmful. The results of this research were published in the American journal Cancer. And the results have now also been published as a poster for education…

Four promising young researchers will be able to conduct two years of research at a university abroad thanks to a Rubicon grant from the Dutch Research Council (NWO). The Leiden laureates are Renske Janssen, Girija Josh, Anne van der Meij and Yana van der Weegen.

Last October, we organized our annual PhD-Postdoc event at Kasteel Oud-Poelgeest. An important part of the program was a speed dating session with LACDR alumni.

Klara Beslmüller

Researchers have discovered the most distant Milky-Way-like galaxy yet observed. Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. This is surprising since, according to our current understanding of…

The discovery of a planet far too large for its sun defies models about the formation of solar systems and planets. In a paper in Science, researchers, including Yamila Miguel of Leiden Observatory, report the discovery of a planet more than 13 times heavier than Earth orbiting the ultracool dwarf star…

The Netherlands Organisation for Scientific Research has awarded a grant of 750,000 euros to the 'Visualising the Unknown in 17th-century Science and Society' project. Researchers will reconstruct how seventeenth-century scientists recorded and shared their groundbreaking microscopic discoveries. We…

Ionica Smeets is planning to give the prize money that she won with the Iris Medal, a prize for excellent science communication, to student projects.

This March, Jara Bouma, Cas van der Horst and Laura Heitman from the Division of Drug Discovery and Safety and Laura de Paus, Richard van den Berg, Anthe Janssen and Mario van der Stelt from the LIC joined forces to determine how some drugs can specifically target the cannabinoid CB2 receptor (CB2R)…

Lecture

In het onderzoek van docent Martijn Nouwen wordt voor het eerst aan het grote publiek blootgelegd hoe de ‘geheime’ Europese Gedragscodegroep er niet in is geslaagd om verschillende vormen van schadelijke belastingconcurrentie uit te bannen.

De Raad van Advies bestaat uit leden die een binding hebben met de faculteit. Daarnaast zijn zij goed thuis in de wereld van de advocatuur, de rechterlijke macht, de overheid en het bedrijfsleven. Het faculteitsbestuur gebruikt de adviezen van de Raad van Advies bij de beleidsontwikkeling van de faculteit…

Not everything that comes close to a black hole is swallowed by it. Black holes can also hurl material away, and that chance turns out to be considerably bigger than previously thought. Martijn Oei's accidental discovery and his subsequent research on it earned him a cum laude promotion on 12 Decemb…