Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.

For already two years, Vincent Niochet has been affiliated with the Leiden Faculty of Archaeology as an external PhD candidate. Now, he has been awarded an NWO PhDs in the Humanities grant, allowing him to continue his research as a paid PhD staff member. ‘The past two years have been quite challenging,…

IBL-researchers revealed in a new study that insects are successful on land because their eggs became protected against desiccation. An extraembryonic membrane in the egg, the serosa, helped insects to make the transition from water to land.

There is greater variety in the size of men’s brains than of women’s. This could help explain why some psychiatric disorders such as ADHD and autism are more prevalent in boys. Leiden brain researcher Lara Wierenga has published an article about this in the international journal Cerebral Cortex.

Tropical butterflies adapt to their environment to improve their chances of survival. The changes are triggered by hormone signals that transmit information about temperature to the butterflies' tissues. Biologist Ana Rita Mateus shows how a complex combination of environment, physiology and genetics…

Researchers from the Institute of Biology Leiden have discovered how good intestinal bacteria regulate our innate immune system. This surprising discovery could make it possible to treat diseases related to inflammation, such as diabetes and colitis, with a cocktail of good bacteria. Publication in…

When university lecturer Martine Bruil was on exchange in Ecuador as a teenager, she fell in love with the area's ancient languages. Now, more than 20 years later, she is starting a research project on the kinship of the language Awapit with the Quechua language that was spread by the Incas.

Curiosity is the driving force behind the research of ecologist Michiel Veldhuis. The associate professor investigates ecosystems in relation to climate change in the savannahs of Africa. More and more, he is also looking at social factors such as the influence of population growth. The KNAW rewards…

Take a walk through any city, and you are likely to come across a brightly coloured mural. Although these paintings often seem to serve solely as a backdrop for Instagram snapshots, art history professor Minna Valjakka says there are rich traditions and intricate histories that uncover more critical…

Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Connecting worlds, enhancing research and teaching, and providing innovative solutions to complex social issues: that is the idea behind interdisciplinary research. In that respect, a huge amount happened at Leiden University in 2023.

Festival

PhD defence

Genes predict whether you have a propensity for an illness but environmental factors often have the last word: nutrition, air pollution, lifestyle, stress. The exposome as both culprit and chance. Large-scale research is being carried out into this at Leiden. Thomas Hankemeier, Professor of Analytical…

In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…

For their research many neuropsychologists use the brain scanners at the LUMC. At the start of the pandemic, the rules for visiting the hospital became stricter and a large amount of psychology research looked as though it would fall through. Thanks to good protocols the researchers can now pick up…

During this last year, most of our efforts and involvement in terms of recruitment activities and events as well as connecting with prospective students, parents and schools has all been moved online. Not a big surprise – this has been the shift for the entire world.

Worldwide, countries are barely prepared for major borderless crises such as extreme natural disasters or other unexpected calamities that destabilise society, Professor of Political Science, Arjen Boin, warns. In his inaugural address on 23 October he makes some recommendations.

In recent years, the public discourse on immigration in Europe and in the United States has often focused on efforts to increase security and restrict traffic on external borders. How old is this phenomenon of states attempting to control migrations on external borders? What were the motives and the…

Prior to arriving to Leiden, Dr. Abazon completed her Ph.D. at Yale University's Department of Comparative Literature, where she also taught courses ranging from Introduction to Zionism to World Cinema.

When migrating from China to Siberia, a few intermediary food stops are not a luxury. For migratory birds, they are even crucial for their survival. However, climate change is altering the seasonal availability of food at these stops. Environmental scientist Yali Si has discovered that because of this,…

Lecture

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

The Institute of Biology Leiden has a new visiting professor as of the first of May. Bioinformatician Marnix Medema holds the Van der Klaauw chair for a year and looks forward to scientific collaborations and to boost the bioinformatics education.

Plants can’t run away from enemies. Still, it would like to keep life-threatening herbivores at a distance. This can be done with odours. Klaas Vrieling of the Institute of Biology Leiden found out with his team how plants change odour production to keep the munchers at a distance.

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden PhD candidate Samuel Schwab has found that the histones in these organisms are much more diverse than previously thought. Schwab and his colleagues describe…

One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…

Effectively treating a severe case of pneumonia is often challenging. Identifying the pathogen behind it can be difficult. PhD candidate Ilona den Hartog tried something new: ‘We searched for answers in substances our own body produces.’ PhD defence on 17 September.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.

Patients with the same illness often receive the same treatment, even if the cause of the illness is different for each person. This represents a new step towards ultimately being able to offer every patient more personalised treatment.

Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.

The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…

A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

Exclusion elicits the same response in children as in adolescents and adults. That is what psychologist Mara van der Meulen found when she studied brain activity in primary schoolchildren. ‘What is new for us is that it is the same in childhood as later in life.’ Doctoral defence on 10 December.

Over hundreds of thousands of years, our region witnessed the comings and goings of various types of hominin. This depended on the temperature as ice ages alternated with warmer periods. In ‘De eerste mensen in de Lage Landen’ (‘The First Humans in the Low Countries’) Leiden archaeologists Yannick Raczynski-Henk…

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.

Researchers from the Plant Ecology and Phytochemistry group at the Institute of Biology Leiden (IBL) received an STW (Stichting Technologische Wetenschappen) grant for applied studies in plant herbivore resistance with potential for a novel resistance test.

Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…

From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…