Key publications of the Quantitative Pharmacology group

To what extent and how do identity processes influence health behavior?

Development of micro-scale analytical tools to be used to address relevant biomedical questions in the field of neuroscience, and other application areas intrinsically dealing with small sample amounts.

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The overall aim of this project is to understand, on the molecular level, how the bacterium V. fischeri cells interacts with their squid host.

The mission of the Plant Sciences cluster is to contribute to the sustainable production of high-quality crops, flowers and high-value bio-based products, and to contribute to the maintenance and restoration of biodiversity in natural ecosystems. This is realised by generating fundamental knowledge…

Key publications of the Predictive Pharmacology group.

In this research line, the role pharmacological agents and neurochemcial processes play in behavior and cognition is examined with a particular focus on pain, placebo and nocebo effects and intensive care treatments.

Africa has a population of 1.5 billion. In 30 years’ time, this will be 2.5 billion. The continent’s impact on the global economy, but also on the environment, will therefore increase drastically. Researchers from the African Studies Centre Leiden (ASCL) have been aware for decades of the crucial role…

The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…

SAILS is a Leiden university wide initiative aiming to facilitate interdisciplinary collaboration on the use of Artificial Intelligence (AI).

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

In July 2022, Leiden hosted the ESOF conference.

Isotopes on exoplanets, a more efficient memory for data centres or new molecules that work against the Zika virus and HIV. Which PhD candidate has written the most impressive dissertation of 2023? The jury of the C.J. Kok Jury Award faces the challenging task of deciding that. Meet the nominees of…

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…

This minor critically examines the complexities of food sustainability through ecological, socio-economic, political, and cultural systems.

The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.

Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

In 2020, Leiden University launched its stimulated interdisciplinary programs, including one focused on regenerative medicine.

Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.

Coordination chemistry is the chemistry of metal atoms

Many dangerous diseases such as COVID-19, Ebola and Q fever have jumped from animals to humans. But it is not only because of these diseases that we should include animals in our health policy, but also because of their right to health, writes PhD candidate Joachim Nieuwland. PhD defence on 13 May.

Dutch mosquitos are more resilient to saltwater than previously thought. Environmental scientist Sam Boerlijst discovered this during his PhD research at the Hortus botanicus. This knowledge is crucial for understanding how mosquito-borne disease transmission might change in the future.

After Columbus landed on the island of Hispaniola (present-day Haiti and the Dominican Republic), the farming culture of the indigenous people quickly disappeared. This has been demonstrated by Leiden archaeologists and colleagues from other universities on the basis of soil research. Publication in…

'The World Upside Down. The Geographical Revolution in Humanist Commentaries on Pliny's Natural History and Mela's De situ orbis (140-1700)', in: Enenkel, K.A.E. & Nellen, H. (Eds.), Neo-Latin Commentaries and the Management of Knowledge in the Late Middle Ages and the Early Modern Period (1400-1700).Humanistica…

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defence 19 December.

Four scientists from the Faculty of Science will receive a grant of up to 50,000 euros in the Open Competition Domain Science - XS from science financier NWO. This category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea.…

Does knowledge of environmental performance change farmer's behaviour?

On Monday 21 September Annemarie Meijer, Professor of Immunobiology, presented her inaugural lecture on immunobiology and infectious disease.

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.

Two years ago, Amanda Henry joined the Faculty of Archaeology’s Archaeological Sciences department. She investigates diet and human evolution, with a specific focus on plant foods. ‘Most of the studies on the prehistoric diet focus on meat and hunting. This just didn’t make sense to me.’

Bringing together scholars from Russia, the United States and Europe, this collection of essays is the first to explore the slippery phenomenon of post-Soviet nostalgia by studying it as a discursive practice serving a wide variety of ideological agendas.

Migration is an important topic of academic, public and political debate. Migration research generates a wealth of articles. The Journal of Migration History (JMH) is the first to specialize in the field. Articles on migration history either appear in journals that specialize on current issues, or in…

In this dissertation Itandehui Jansen examines the ‘Voice’ of the filmmaker from a political and aesthetic perspective.

Leiden University has secured an impressive 12 European exchange grants. This is good news for students, lecturers and researchers from home and abroad.

The research project addresses the question how complaints in the voluntary youth care system are dealt with on the municipal level and what role (municipal) Children’s Ombudspersons play in this context, through qualitative research methods.

CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

Hermelijn Smits is Professor of Host-commensal Interactions and Immune Modulation. In this role she is increasing our current understanding of the way in which microbes and parasites shape our immune system to protect us from respiratory infections and chronic inflammatory diseases. In her inaugural…

Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…

No two pandemics are ever the same. The current coronavirus crisis, for instance, is clearly very different from the deadly plague outbreaks in the 14th and 15th centuries. Can historians learn anything from the coronavirus crisis? And what can we learn at the moment from historians? These are questions…

Having a bachelor, master and Ph.D in chemistry, Elena Sánchez López shifted to a more biological research for her postdoc. All of her studies she did at the University of Alcala, in Spain. Way back in medieval times, this city was the place of birth of Miguel de Cervantes, author of the world famous…

Mysterious protein fibers show up in the brain cells of people suffering from Alzheimer’s' disease and other neurodegenerative disorders. Leiden physicist Louise Jawerth has been awarded a Vidi grant to find out how these fibers form in the first place.

Researchers from Leiden University, McMaster University and Public Health Ontario are calling on colleagues to track down archival specimens of mosquitoes from museums and other collections and to examine them with modern methods. This will tell them more about malaria transmission.

If you imagine in advance that something is not going to hurt, this could mean you experience less pain. This discovery was made by health psychologist Kaya Peerdeman during her PhD research on the placebo effect. PhD defence 7 February.

Jan Melissen, Senior Fellow International Relations and Diplomacy at ISGA, researched the topic of consular diplomacy in a digital age. Specifically: the communicative challenge.