In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

As an educational and research institution Leiden University is seeking to understand its own relationship with the colonial and slavery past.

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Studying change in the course of human history, in different places, through the lens of a diverse set of core themes; World History for International Studies offers readers a set of windows into different debates historians have been conducting.

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?

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Business Studies spans science, medicine, and business, focusing on areas such as technology management, innovation, entrepreneurship, operations, and decision making.

List of Support Departments at LION and the Faculty of Science

Religion in the ancient world, and ancient Egyptian religion in particular, is often perceived as static, hierarchically organised, and centred on priests, tombs, and temples. Engagement with archaeological and textual evidence dispels these beguiling if superficial narratives, however. Individuals…

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Global Transformations and Governance Challenges (GTGC) at Leiden University aims to advance knowledge and practice on how we govern – and could govern – major world-scale changes in contemporary society. These global transformations include hegemonic and other geopolitical shifts, ecological changes,…

At Leiden University, students with enquiring minds are encouraged to take on an extra challenge alongside their regular studies. Master Honours Classes & Challenges are small-scale, interdisciplinary courses that revolve around tackling a complex issue for society or a partner organisation.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

The aim of this PhD dissertation project is to study the effect of private foreign investment outside the realm of economics in the context of a colonial structure in Indonesia between c. 1910 and c. 1960.

PNAS publication on protein encounter complexes

Muhammad Adlin Sila examines the range of ways Bima Muslims constitute their Islamic identities and agencies through rituals and festivals. In response to their surroundings, what it means to be a Muslim is constantly being negotiated.

This monograph, written by dr. Dennie Oude Nijhuis and published by Cambridge University Press, discusses the postwar development of the welfare state.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

From Complex Hunter-Gatherers to Early Urban Societies

Assessing and implementing new diagnostics strategies for stratifying patients

Living together in a residential setting adds another dimension to this learning, as our students have to learn to live with others who may not share the same daily routines or standards.

The unit Health, Medical and Neuropsychology offers eduction and conducts research on related fields of Health, Medical and Neuropsychology.

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Leiden University gives inquisitive students the opportunity to follow an extra programme or classes alongside their regular bachelor’s programme. These are called Honours College and Honours Classes.

Mr. Ade Jaya Suryani defended his thesis on 28 January 2021

We investigate the physics and design of mechanical metamaterial, intricately sculpted materials with properties set by their architecture.

This study presents a full descriptive account of the grammar of Mualang, covering the major features of phonology and morphosyntax as well as issues related to pragmatics.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

Japan's Occupation of Java in the Second World War draws upon written and oral Japanese, Indonesian, Dutch and English-language sources to narrate the Japanese occupation of Java as a transnational intersection between two complex Asian societies, placing this narrative in a larger wartime context of…

The MCS research group members and their research are closely affiliated with the two Leiden master’s tracks in Museum Studies offered at the Art History and Archaeology departments.

The project 'Food citizens?' examines the consequences and premises of collective food procurement in three European cities (Rotterdam, Turin, and Gdańsk).

The Leiden Institute of Advanced Computer Science (LIACS) is a centre of excellence for multidisciplinary research and education in computer science and artificial intelligence (AI).

How do people experience ‘inclusion’ in sports? How can experiential expertise enhance policies in sport and inclusion? This research internship at The Mulier Institute enables a student to investigate these issues from a qualitative research perspective.

Subproject of

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

Promotor: E.F. Smets, Co-promotor: J. Geml

This collaborative research group (CRG) facilitates the synergies of researchers engaged with African languages and documentation of texts conducted in East Africa, paying particular attention to ‘endangered archives’ and ‘endangered languages’.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen