Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.

Seven Leiden researchers have each been awarded a Vici grant by the Netherlands Organisation for Scientific Research (NWO). This will enable them to form a research group and develop their own innovative line of research.

When internist Christian Blank made his very first discovery, his field of immunotherapy was the underdog of cancer research. Now, over 20 years later, Blank has been appointed Professor By Special Appointment of Internal Medicine for his clinical research into immunotherapy and will give his inaugural…

Lecture

Commission on Legal Pluralism - Keynote Lecture

A team of researchers at the Institute of Biology Leiden, in collaboration with scientists from Utrecht University, has discovered a novel approach to improve the production of antibiotics and enzymes in the soil bacteria Streptomycetes.

Publication by: Vanessa Frodermann, Janine van Duijn, Gijs van Puijvelde, Peter van Santbrink, Max Lagraauw, Margreet de Vries, Paul Quax, Ilze Bot, Amanda Foks, Saskia de Jager and Johan Kuiper. Journal of Internal Medicine. 2016;279:592-605.

PhD defence

Debate, Panel and Q&A session

VVI Research Meetings 2023-2024

A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…

The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.

Like ants, termites and bees, some bacteria work together as a multicellular group. There is a strict division of labour in such colonies, to make the group more resilient to the outside world. Now researchers have found that some parts of the bacterial colony can take ‘for the greater good’ to a whole…

Specific fatty acid-sugar molecules allow leprosy bacteria, among others, to hide from our immune system. How exactly is not entirely clear. Hessel van Dijk, who received his PhD on 13 October, replicated the molecules, helping to solve a piece of the puzzle. Van Dijk's dissertation is titled: Synthesis…

Late in 2015 a woman gave birth to a baby conceived following the reimplantation of thawed ovarian tissue. The woman was able to become pregnant thanks to transplantation of the tissue that took place in the LUMC.

Remko Offringa, Associate Professor in Plant Developmental Genetics, and Associate Professor in Molecular Microbiology Arthur Ram both have been appointed as the new Directors of Education at the IBL. Offringa in the role as Director of Education for the Master program and Ram as Director for the Bachelor…

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

Lecture

With a grant from NWO, Thomas Hankemeier will develop new methods to better understand the dynamics of the building blocks of life, such as cells, enzymes, and metabolites. He does this together with the University of Amsterdam and a number of companies.

Digital journalism is transforming the way in which information and communication technologies are used by media workers. With this change journalist practices, norms and values are also being reshaped. This is the conclusion of Tomás Dodds PhD research.

The article that was published on 21 January 2020 claims that chip maker ASML wants to be able to export to China but has been unable to obtain the necessary permits. Last summer, the application by the Dutch Ministry of Foreign Affairs (BZ) was suddenly frozen after pressure from the USA, according…

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…

Already during their bachelor’s programme, students in Pharmaceutical Sciences are presented with challenging projects. One of these is the Bachelor Research Assignment (BOO in Dutch), which is often their first real experience with scientific research. This means a lot of responsibility and failures,…

Leiden PhD student Xuequan Zhou has designed a new promising molecule that efficiently kills cancer cells, but does not harm healthy tissue. The trick: the drug is only active when irradiated with light. Zhou’s new compound does this extra efficiently by cleverly self-organising into nanoparticles.…

A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…

Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?

From the Spanish Flu during WWI to COVID-19: the role of the American government in these Pandemics. Professor Giles Scott-Smith, who together with Dario Fazzi and Gaetano Di Tommaso completed the book project Public Health and the American State, discusses a century of American responses to health…

Lecture

Recently, Jaap van den Herik, professor emeritus Law and IT, was interviewed by the BNVKI (Benelux Association for Artificial Intelligence).

In otherwise energetic desserts at the bottom of the sea, researchers have found oases where microbes can harvest energy. Remarkably, the microbes first have to be buried under starving conditions for 80,000 years. An international group of researchers, amongst them José Mogollón from the Insitute of…

The ERC has awarded a Starting Grant to five promising researchers from Leiden. Two are from the Faculty of Social and Behavioural Sciences, one is from the Faculty of Humanities/Governance and Global Affairs, one from the LUMC and one from the Faculty of Science.

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

In an unpredictable environment bacteria evolve the same strategy as shareholders who try to protect themselves against unpredictable swings in the stock market. Experimental evolution biologist Dr Bertus Beaumont published an article on this discovery on 5 November in the journal Nature.

Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…

Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…

Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…

Although Ebola is a virus with significant fatality rates, we still lack effective countermeasures to battle it. To change this, Alireza Mashaghi and his colleagues from the Leiden Academic Centre for Drug Research have successfully developed an organ-on-a-chip model that imitates the most dangerous…

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.

Α-synuclein, a protein associated with Parkinson’s disease, proves to bind with membranes in a surprisingly efficient way. It confirms scientists’ suspicion of the protein’s leading role in the transmission of neurotransmitters between nerve cells in the brain. Publication in PLoS ONE.

The High Troughput Microscopy Dutch Flagship Node that includes the Leiden Cell Observatory Screening platform is now officially ratified as a Euro-BioImaging (EuBI) Node Candidate

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defence 19 December.

How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.

The first phase of the construction of the new building for the Faculty of Science is finished. The Cell Observatory of the Institute of Biology Leiden will be moving to the new building on the 19th of May.

Amanda Foks (Division of BioTherapeutics) has been awarded a Horizon 2020, ERA-CVD joint transnational cardiovascular research grant. She will lead a consortium consisting of early career European scientists (Dimitrios Tsiantoulas, Medical University of Vienna, Austria; Julia Polansky-Biskup, Charité…

A collaboration between the IBL and LUMC has resulted in the discovery that the polymerase theta enzyme is essential for the integration of Agrobacterium T-DNA into the genome of plants. The finding means a break-through for the development of more efficient systems for targeted genome modification…