1,224 search results for “effective date development” in the Public website
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Of Marks and Men
Daniel Soliman defended his thesis on 15 September 2016.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Do common antibiotic treatments influence emotional processing?
People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.
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Polycentrism: How Governing Works Today
How does governing work today, and how does society handle pressing challenges in ways that are democratic, effective, fair, peaceful, and sustainable?
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Plant-microbe interactions
Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?
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Introduction to Medieval Europe 300–1500, Third Edition
Introduction to Medieval Europe 300–1500 provides a comprehensive survey of this complex and varied formative period of European history, covering themes as diverse as barbarian migrations, the impact of Christianisation, the formation of nations and states, the emergence of an expansionist commercial…
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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‘Archaeology is quintessentially interdisciplinary'
Professor of Archaeometry Patrick Degryse analyses archaeological finds using techniques from chemistry, physics and biology. He will give his inaugural lecture on 19 February. He reflects on three interesting propositions from his lecture.
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'Contemporary Arts in and for Civil Society' in 'Routledge Handbook of Civil and Uncivil Society in Southeast Asia'
'The Routledge Handbook of Civil and Uncivil Society in Southeast Asia' explores the nature and implications of civil society across the region, engaging systematically with both theoretical approaches and empirical nuance for a systematic, comparative, and informative approach.
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Early signs for good mental health during adolescence: Emotional Intelligence matters
In a longitudinal study, Eichengreen and colleagues explored how the certain aspects of emotional intelligence impact the development of adolescents’ mental health, thus identifying potential warning signs and targets for intervention programs. Despite a higher risk for mental health issues and lesser…
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Leiden breakthrough in research on nanotherapy
Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.
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Spinoza prize for 'migraine professor' Michel Ferrari
Neurologist Professor Michel Ferrari has been awarded the Spinoza prize. 'In biomedical research you can only make breakthroughs at the borders between sciences,' according to Spinoza, doctor and scientist. 'This prize is proof that co-operation works.' Together with clinical and fundamental researchers…
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Risks of big data not clearly identified in GDPR
The General Data Protection Regulation (GDPR) came into force in 2018. It was intended to protect the rights and freedoms of individual citizens from the risks of personal data processing. Meanwhile, the phenomenon known as big data has continued to advance at a fast pace. PhD defence on 12 Septembe…
- SAILS Lunch Time Seminar: Applications of Artificial Intelligence in Early Drug Discovery
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How a Spanish post-doc brings her expertise in chemistry to Leiden genetics
Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…
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Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
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Squaramide-based supramolecular polymers
PhD defence
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Will AI be listening in on your future job interview? On law, technology and privacy
The law and Artificial Intelligence (AI) applications need to be better aligned to ensure our personal data and privacy are protected. PhD candidate Andreas Häuselmann can see opportunities with AI, but dangers if this does not happen.
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War in Europe
Conference
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Leiden Leadership Lunch: Changing Service Professionals' Attitudes to Volunteers
Lecture
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Dies natalis: ‘Collaboration requires firm grounding in the individual disciplines’
‘Collaboration is increasingly important,’ Rector Magnificus Carel Stolker said at the 445th Dies Natalis of Leiden University on 7 February. But, as he heard from a number of Leiden researchers, this is contingent upon a firm disciplinary basis. A novelty of this year’s celebration was a joint dies…