1,487 search results for “global gene regulation” in the Public website
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It’s all about the cell wall for brand-new professor Dennis Claessen
Dennis Claessen has been appointed professor of Molecular Microbiology at the Institute of Biology Leiden. With his teaching and research on the cell wall, the professor wants to establish applications in the industry and the medical sector.
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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GTGC conference on the pressing social issues of our time
Major developments worldwide are creating new challenges for society. The pandemic has hit us hard, for example, and we are already feeling the effects of global warming. How can society and politics deal with the urgent problems of our time? That is the theme of the Global Transformations and Governance…
- Open Science Week - at the Governance and Global Affairs Faculty
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Industry (ab)uses the Legal System: The Urgent Call for Binding Regulations to Protect People and Climate
Debate, Roundtable discussion
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Introducing Historians Without Borders
In the summer of 2015 the former Finnish foreign minister Erkki Tuomioja, together with a group of Finnish historians, took an important initiative and established the organization Historians Without Borders (HWB).
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Statistical ‘rockstar’ Brad Efron opens Leiden statistics centre
He is said to be one of the greatest living statisticians. Bradley Efron gave a lecture in Marekerk and opened LUXs, the Leiden University Center for Statistical Science, the first university statistics centre in the Netherlands.
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Sebastian Pomplun joins Oncode Institute to accelerate breakthroughs in cancer research
Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…
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ERC Starting Grants for five young researchers from Leiden University
The ERC Council has awarded Starting Grants to five promising Leiden researchers. With an impressive three laureates, the Faculty of Social and Behavioural Sciences has done particularly well. The fourth grant goes to the LUMC and the fifth to the Faculty of Governance and Global Affairs.
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Wood formation further explored by NWO-XL grant
Leiden researchers, Professor Remko Offringa and co-applicants Salma Balazadeh and Frederic Lens received an NWO-XL grant (2.5 million euros). Together with researchers in Wageningen and Groningen, they will study the genetic and environmental drivers of woodiness. From plant to molecule, the groups…
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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New insights for improved pertussis vaccines - Press release -
Researchers in Bilthoven, The Netherlands, have recently unraveled the defense against whooping cough bacteria in unprecedented detail. The outcome of the project, conducted at Intravacc (Institute for Translational Vaccinology) in Bilthoven, provides opportunities for a new approach in the development…
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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Hunt for fundamental insight into and treatment for cancer
To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.
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King of Sweden visits Leiden University
Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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Leiden: The scene of the Zebrafish Disease Models conference 2018
In July, 2018, the Institute of Biology Leiden hosted the 11th conference of the Zebrafish Disease Models Society (ZDMS), an international association dedicated to the advancement of basic and clinical research using zebrafish disease models. More than 350 researchers from all over the world gathered…
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Omid Karami wins Krijn Rietveld Memorial Innovation Award
Plant scientist Omid Karami is the first winner of the Krijn Rietveld Memorial Innovation Award. The jury praises the outstanding quality of his scientific research as well as the positive societal impact and commercial potential of his work.
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New cell therapy facility at Leiden Bio Science Park
American pharmaceutical company Bristol Myers Squibb will be building a new (CAR-T) cell therapy facility in the Oegstgeest part of the Leiden Bio Science Park. The company will manufacture and develop CAR T-cell therapy for patients with blood cancer (leukaemia), for example.
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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Leiden discovery evaluated by world-leading breeding companies
Various companies in the plant biotech industry will test a recent Leiden discovery in their crops. The ‘Pol Theta’ technology is developed in Leiden and makes it possible to reduce undesired side effects during genome engineering of plants.
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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Engaging with climate diplomacy: Lessons from Dutch UNFCCC Negotiators
Discover the unique Vital Interests course in the BSc Security Studies programme, featuring an inspiring session on climate diplomacy with Dutch UNFCCC negotiators.
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The internet has many bosses. It’s chaotic but it works
Governance of the internet is chaotic, says Professor Jan Aart Scholte. Can we learn from this relatively new form of governance?
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Interactions Meeting: Legitimacy as lens to study the governance of global citizenship education
Conversation
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EIC Pathfinder Challenge grant for research into autoreactive B cells in cardiovascular disease
At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.
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Cell-based medicinal products: grant rejected, paper published
Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.
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DNA dating at Lowlands
Why do opposites attract? According to Karin van der Tuin, researcher at Leiden University Medical Center (LUMC), it could be because of your DNA. The more you differ from one another, the better. She will be testing her ideas at the Lowlands festival Lowlands, where she will subject visitors to DNA…
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Two researchers receive Rubicon grant for research abroad
Uncovering ageing processes in the brain and research on the use of the word ‘that’. Thanks to a Rubicon Grant, two Leiden researchers who were recently awarded their PhDs will be able to conduct research at a research institute abroad.
- GTGC lunch seminar: Eve Darian-Smith and Phil McCarty on Global Studies Methods
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Where does the hegemony lie in the 21st century?
The book: Hegemony and World Order: Reimagining Power in Global Politics will be published this week. Jan Aart Scholte: 'We hope that students, lecturers and policy makers will start to think differently because of this book'
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Researchers agree: the future of AI must be human
What rules should regulate AI, who should make them, and how will they be enforced in the digital arena?
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Something else than writing an essay: Ruben made a documentary for an assignment
Ruben van Gaalen used a very unique approach for a course of the research master Colonial and Global History: instead of writing an essay, he went to Dublin and made a documentary about African rappers in Ireland.
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Monitoring Migrations: The Habsburg-Ottoman Border in the Eighteenth Century
How old is the phenomenon of states attempting to control migrations on external borders? What were the motives and outcomes of these policies? In his dissertation, Jovan Pešalj examines how migration control on the southern Habsburg border emerged, how they functioned, and what impact they had on migrations.…
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Striking a Balance between Local and Global Interests
PhD defence
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Summer school 'Socioeconomic diplomacy and global empire building, 16th-19th centuries'
Conference, Summer School
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Roundtable: Is the Russia-Ukraine War a Global War? / Workshop: Archives and Methods
Conference, INVISIHIST Pre-Conference
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GI grants awarded to Mariana Francozo, Sabine Luning and Wayne Modest
Global Interactions is pleased to announce that we have awarded a GI Advanced Seminar grant to Dr. Mariana Francozo (Archaeology) for 'Historia Naturalis Brasiliae' and a Breed Grant for 'Global Earth Matters' to Dr. Sabine Luning (CA-DS) and Dr. Wayne Modest (RCMC)
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Volume on Internet Governance published
In March 2021, Prof. dr. Jan Aart Scholte, Professor Global Transformations and Governance Challenges at Leiden University, co-edited with Dr. Blayne Haggart and Dr. Natasha Tusikov the volume Power and Authority in Internet Governance.
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The New Atlantic Order - and Transformation of Global Politics in the "Long" 20th Century
Lecture, Global Questions Seminar
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Security and Global Affairs: Reflections on Research, Education and Academic Management
Inaugural lecture
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Field Notes: An Interactive Session on Housing, Land, and Property in Global Hotspots
Debate
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From Baghdād to Baghpūr: Global Blackness in Medieval Arabo-Asia
Lecture, Research Seminar Europe 1000-1800
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Auxin
Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.
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Theory
Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Public Event ‘Will the EU be a relevant Global Actor in the Future’?
Conference, Public Event
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Alternative? Examining the Emerging Role of Chinese NGOs in China's Global Development Footprint
Lecture, Lunch Research Seminar