3,099 search results for “cancer drug discovery initiatief” in the Public website
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Optimal Teaching
The better teaching is for pupils and students, the more solid the basis will be that we give them for their future careers. This type of teaching requires strong instructors and insight into the best ways in which pupils can be supported, and research at Leiden University is making a contribution in…
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Healthcare and population health: AI research in Leiden, Delft and Rotterdam
‘Our health is the area that stands to gain most from artificial intelligence.’ The three universities in Zuid-Holland are helping make these gains. Three researchers talk about their collaborative research into AI for health, drug discovery and healthcare in the AI knowledge cluster in Zuid-Holland.…
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Text-mining real-world data to evaluate systemic anti-cancer therapy
PhD defence
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TGF-β signaling dynamics in epithelial-mesenchymal plasticity of cancer cells
PhD defence
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Attitude Switch: unraveling breast cancer cell-intrinsic mechanisms that manipulate the immune system
PhD defence
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Partial Breast Irradiation in elderly patients with early-stage breast cancer
PhD defence
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The impact of one: single cell analysis of T cell states in human cancer
PhD defence
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Systems biology as a compass to understand cancer-immune interactions in humans
PhD defence
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Light therapy for cancer-related fatigue in (non-)Hodgkin Lymphoma Survivors
PhD defence
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Metabolomics and lipidomics applications in the context of immune and cancer metabolism
PhD defence
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Supporting women with breast cancer in making an informed decision about immediate breast reconstruction
PhD defence
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the response to immunotherapy in patients with non- small cell lung cancer
PhD defence
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The T cell-myeloid axis in the success and failure of cancer immunotherapy
PhD defence
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Colorectal cancer screening for average- and high-risk individuals Beyond one-size-fits-all
PhD defence
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Pancreatic cancer: Chasing the light at the end of the tunnel
PhD defence
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Immunosuppression in breast cancer: a closer look at regulatory T cells
PhD defence
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Untangling the immune landscape of colorectal cancer by in situ multiplex immunophenotyping
PhD defence
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Molecular imaging of pancreatic and rectal cancer - Towards optimized detection and response prediction
PhD defence
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Sexual Health Care in Prostate Cancer for Men and their Partners
PhD defence
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Targeting MHC-I related proteins for cancer diagnosis and therapy
PhD defence
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SPECT/CT-guided elective nodal irradiation for head and neck cancer
PhD defence
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The role of the Bone Morphogenetic Protein Pathway in Colorectal Cancer
PhD defence
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pharmacogenetics of systemic and intraperitoneal chemotherapy in colorectal cancer
PhD defence
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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Science
There are eight institutes at the Faculty of Mathematics and Natural Sciences:
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Lectures at Science
From black holes to artificial intelligence and from drug research to data science: welcome to the fascinating world of the Faculty of Science. Our researchers, students and guests regularly give public lectures about their work. You are welcome to attend.
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Awards and Grants 2017
An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.
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From data to discoveries: machine learning and optimization in space
Lecture
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Capillary Electrophoresis-Mass Spectrometry for Metabolomics
In the field of metabolomics, capillary electrophoresis-mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In order to highlight the unique features of CE-MS for metabolomics studies, Dr. Rawi Ramautar…
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Gerard van Westen wins KNCV Gold Medal
Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'
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Leiden University and LUMC strengthen ties with Janssen pharmaceutical company
Leiden University, the LUMC and Janssen have signed a partnership agreement stating that they will collaborate in different areas, including infectious disease prevention, clinical tests, drug production and e-health. By joining forces, the three partners will be able to provide better, more innovative…
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Bone and joint disorders: Screening and early clinical drug development
PhD defence
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mRNA and Drug Delivery with Lipid-based Nanoparticles
PhD defence
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pharmacology studies investigating novel formulations of dopaminergic drugs
PhD defence
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The Nobel Prize in Chemistry went to an AI model (and rightly so)
Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…
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The EPIC Alliance joins forces to combat antibiotic resistance
No, this isn’t about a Star Wars Alliance that wants to suppress The Resistance. Rather, the EPIC Alliance brings together scientific experts from seven countries to address the growing threat of antibiotic resistance. Leiden professor Nathaniel Martin is part of the 11-member consortium.
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In Memoriam Professor Huib Ovaa
On the 19th of May 2020, our dear colleague and friend Professor Dr. Huib Ovaa has passed away from prostate cancer. Last summer Huib became ill, and in first instance it appeared that he had attracted a relatively harmless infectious disease. Unfortunately, it became soon apparent that he suffered…
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Leiden Science Young Talent Award
The Leiden Science Young Talent Award is awarded yearly to a student who completed their bachelor’s degree with an excellent thesis.
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Development of an intradermal tuberculosis vaccine by combining dissolvable microneedle arrays and Mycobacterium tuberculosis antigen-containing
Mycobacterium tuberculosis (Mtb), the pathogen causing tuberculosis (TB), is the leader among all pathogens responsible for the most human deaths today and it is considered as one of the top 10 causes of death worldwide. There is an increasing occurrence of multidrug-resistant and even totally drug-resistant…
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Serkan AslanScience
s.aslan@lacdr.leidenuniv.nl | 071 5275919
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Vat op stabiele bloedvaten
Inaugural lecture
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Research Facilities
Our Division has created and maintains the Visualisation Core Facilities of the LACDR. This is a multi-user facility offering basic and advanced microscopic techniques to scientists of the LACDR.