209 search results for “vries middeleeuwse begraafplaatsen” in the Public website
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Healthcare
Training and learning in the field of Health Care
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Public perception of terrorism attacks: A conjoint experiment
This article researches the public perception of terrorist attacks by measuring the importance the public assigns to attributes of terrorist attacks.
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Predicting early Alzheimer's disease stage in human
A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).
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Toekomstdromen
Serie workshops waarin mensen werkzaam op het terrein van Midden-Oosten- en islamstudies vertellen over hun ervaringen in de praktijk.
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The Impact of Name Writing on Early Literacy
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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Regulation of enzyme production in fungal cell factories
Our object is to identify and characterize transcription factors involved in lignocellulosic biomass degradation in the filamentous fungus Aspergillus niger.
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De aanpak van ondermijning en financieel-economische criminaliteit
Deze onderzoeksgroep richt zich op het thema ondermijning en financieel-economische criminaliteit, in het bijzonder de aanpak ervan op een aantal deelterreinen.
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The Sand Motor - Building with Nature to optimise coastal protection and other ecosystem services
How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?
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Key publications
Key publications of the Cardiovascular Pharmacology group
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The Nature of the Workmen's Marks and Their Interaction with Writing
The project concerns the nature, the usages and functions of pictographic systems in relation to writing in societies with (restricted) literacy.
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Selectivity
Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.
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Save the date: Mmmonk School 2024
Mmmonk en het Henri Pirenne Instituut voor Middeleeuwse Studies (UGent) organiseren eind 2024 de tweede editie van Mmmonk School: Lessen voor gevorderde beginners rond het middeleeuwse boek. Mmmonk School biedt een interdisciplinair praktijkgericht programma over middeleeuwse Vlaamse manuscripten. Experts…
- Young Academy Leiden Outreach Grant
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Join-in courses 2024-2025
Join-in courses zijn MA-cursussen over middeleeuwse onderwerpen gegeven binnen vastgestelde MA-programma's van de zes deelnemende universiteiten van de Onderzoekschool. Op aanvraag zijn deze vakken toegankelijk voor studenten van andere (Nederlandse) universiteiten. De cursusbelasting en het aantal…
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Medical Systems Biophysics and Bioengineering
The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.
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Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines
Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)
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Public leadership as a balancing act? How leaders’ context influences leadership
Public leadership received increasing attention, but we still do not understand how the context of public leaders affects leadership. This research project delves into public leaders’ perceptions of the leadership situations they find themselves in, which are characterised by multiplicity – one could…
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Non-take-up of social support and the implications for social policies
This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.
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Governance of Innovation Project Management: Necessary and Neglected
Promotores: B.R. Katzy, J. de Vries, Co-Promotor: L.P. Groenewegen
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Targeted Informed consent: empowering young participants in medical-scientific research
Promotor: J.M. van den Broek Co-promotor: M.C. de Vries
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Prof. dr. J.D. Speckmann prize
Annually the Institute of Cultural Anthropology and Development Sociology awards the Speckmann prize for the best Fieldwork NL report, as well as the most accomplished master’s thesis.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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About us
The Faculty of Archaeology at Leiden is the leading academic institute for Archaeology in the Netherlands, and one of the largest in the world. The Faculty is an international front-runner, in the top ten of the QS World University Ranking, at subject level.
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Podcast tips for Pentecost
Are you looking for some listening material for the upcoming long weekend? Staff members and alumni of the Faculty of Humanities have been creating various podcasts over the last few months. A selection is shown here:
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Allosteric Modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…
- In Memoriam
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Vacancy: PhD history of architecture (KU Leuven)
Het Departement Architectuur (Faculteit Ingenieurswetenschappen, Campus Heverlee KU Leuven), zoekt kandidaten voor het project: “Verloren middeleeuwse forten in de Lage Landen ontsloten in 3D”. Het betreft een volledig gefinancierde doctoraatsbeurs in het veld van de architectuurgeschiedenis. Deadline…
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Online Signumsymposium
In de ochtend van 6 november 2021 organiseert Signum een online symposium over het Delftse kartuizerklooster getiteld "Initiatiefnemers, draagvlak en materiële representatie van middeleeuwse kloosters. De casus van de Delftse kartuis". Deelname is gratis, maar aanmelden is noodzakelijk via patricia.stoop@uantwerpen.be.…
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Fabiola van Dam - Dissertation (Utrecht)
On 4 December 2020 Fabiola van Dam will defend her dissertation "Het middeleeuwse openbare badhuis, fenomeen, metafoor en schouwtoneel" (Utrecht). To attend this event online please send an email to: fab.dam@usa.net (mentioning "4 dec" in the subject line).
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New comic on the Middle Ages
Op 2 juni verscheen ter gelegenheid van ‘900 jaar Utrechtse stadsrechten’ een stripboek van het Utrechtse stripcollectief "De Inktpot" over een paar eeuwen middeleeuwse Utrechtse (familie)geschiedenis. Als inhoudelijke adviseurs waren daarbij de mediëvisten Kaj van Vliet en Martine Meuwese betrokken…
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The Postal Imagination: Returning Mail in Contemporary Culture
How to understand the simultaneously dis- and reappearance of letters in contemporary culture, and how does this Neo-Epistolarity relate to media-technological change?
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Towards a comprehensive understanding of (facilitating) teacher professional development
What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.
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Receptor Residence Time
Research question
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Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
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Book presentations
Now and then we organise book launches to present the latest publications, both academic and popular, in our broad field.
- Neerlandistiek Master Universiteit Leiden
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Inaugural lecture: Mariken Teeuwen (Leiden, 12 januari 2024)
On Friday, January 12, 2024, at 4:15 PM, Mariken Teeuwen, endowed professor at Leiden University, will assume the professorship with an inaugural lecture, titled "Perkamenten personen. De stratigrafie van het middeleeuwse boek." Interested individuals can register via the link below.
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Seminar 'Dievenland: De spelregels van een publieksboek' (online)
Het bredere thema van de bijeenkomst (7 december, 16:00-18:00, online), geleid door Janna Coomans (Utrecht), is: hoe kan je op basis van middeleeuwse bronnen een publieksboek schrijven, en in hoeverre verschilt zo’n werk van een academische studie? We zullen een eerste concept van een boekproject bespreken…
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Tentoonstelling Fries Museum
De tentoonstelling 'Vrijheid, Vetes, Vagevuur' is tot en met 7 mei 2023 te zien in het Fries Museum. De tentoonstelling en de bijbehorende publicatie worden samengesteld door Diana Spiekhout, conservator terpencultuur en middeleeuwen. Spiekhout promoveerde in 2020 aan de Rijksuniversiteit Groningen…
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Voorstelling - Het Land van Belofte
Tussen 14 en 30 september 2022 wordt Het Land van Belofte gespeeld door Theatergroep De Kale. Het Land van Belofte neemt u mee naar de groteske verhaalwereld van middeleeuwse pelgrims naar het Heilig Land. Het Land van Belofte is gebaseerd op het zestiende-eeuwse tafelspel Schipper, Pelgrim en Post.…
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Symposium: Kronieken 1400-1850 (VU Amsterdam, 4 oktober)
Op 4 oktober vindt op de Vrije Universiteit het symposium "Kronieken, 1400-1850" plaats. Dit symposium wordt georganiseerd ter ere van het verschijnen van de handelseditie van het proefschrift van Peter Bakker. Drie VU-historici belichten hun onderzoek naar dit onderwerp vanuit verschillende hoeken.…
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Registratie Mmmonk school geopend
De inschrijvingen voor de Mmmonk school zijn geopend. Mmmonk School biedt een interdisciplinair praktijkgericht programma over middeleeuwse Vlaamse manuscripten. Experts geven een inleiding bij de belangrijkste concepten, methodes en vaardigheden uit hun discipline. De lessen zijn online, gratis, en…
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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‘First determine goals, then make healthcare choices’
What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made. This is what Martine de Vries, Professor of Normative Aspects of Medicine, advocated during her inaugural lecture on Friday, 2 November 2018.
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Key publications
Key publications of the Predictive Pharmacology group.
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.