Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.

How can the Safe and Sustainable by Design (SSbD) framework developed in the SSbD4CheM project facilitate the creation of safer and more sustainable chemicals and materials across various industries?

Mrs. Dr. Constance (Stans) Eikelenboom passed away on Sunday, March 12th, at the age of 95. She was the founder of the 'Stans Award', a prize which every year has been given to the best student article of the Institute of Environmental Sciences (CML).

From the Republic of Moldova to Italy and from Indonesia to Greece, students from all over the world participated in the Bio-Pharmaceutical Science Summer School 2017. The students got a comprehensive overview of the education and research performed within the LACDR. ‘I am very happy to be here,’ says…

Venture capital investors Zeeuws Investerings Fonds and Participatiemaatschapij Oost Nederland have joined forces with national and regional partners to fund development and sales of MIMETAS’ unique 3D disease- and tissue modelling technologies.

- How to deconvolute metabolic mixture of precursors and products by biontransformation? - How to optimize the reaction conditions to produce bioactive compounds in biotransformation? - What is the effect of co-treating fungi or bacteria for biotransformations?

It's now possible to measure how many plastic particles there are in our food. Chinese scientists and Leiden professor Willie Peijnenburg applied their new method to lettuce and wheat. Their results were published January 20 in Nature Nanotechnology.

Italian nurse Daniela Poggiali was arrested and convicted of murdering two hospital patients in 2014. Her case attracted the attention of Leiden statistician Richard Gill. After his investigation, together with an Italian colleague, Poggiali was acquitted last autumn. Together with fellow statisticians,…

Overview of the publications of the department of Environmental Biology (1972-2015)

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

How do societies move forward with sustainable, effective and efficient management of Earth's water resources?

Seventeen Leiden University scientists appear on the 2019 Highly Cited Researchers list, which was announced on 19 November by Clarivate Analytics.

The Minister of Education, Culture and Science has approved the application for the master’s programme in Pharmacy in Leiden. This is an important step on the road to a new master’s programme.

The large-scale project NanoInformatics will assess the risks associated with nanoparticles. The project will be funded by the EU with 6.8 million euros and was launched at the beginning of this year. Three scientists from Leiden are involved. 'For the first time, this project combines the various experts…

How do you count the nanoplastics in your body? Leiden researchers published a method in Nature Protocols today that should make this easier. Important for both environmental and medicine research.

Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…

On the brand-new Leiden Teachers Blog, Leiden teachers share their experiences with educational innovation. They show colleagues, students, and everyone else who is interested the different facets of creating university education.

No, this isn’t about a Star Wars Alliance that wants to suppress The Resistance. Rather, the EPIC Alliance brings together scientific experts from seven countries to address the growing threat of antibiotic resistance. Leiden professor Nathaniel Martin is part of the 11-member consortium.

From filtering UV light in sun cream to preventing perspiration odour in socks and sterilising fridges and washing machines. The use of nanoparticles in products is increasing. But what is the impact of these miniscule particles on the environment?

The ‘Stans Prize 2017' (for the best thesis, report or article produced by a CML student) has been awarded to Davide De Mauro. Other CML prizes were awarded to Jeroen Guinee, Reinout Heijungs, Martina Vijver, Willie Peijnenburg en Kevin Groen

Overview of the publications of the department of Industrial Ecology (1982-2015)

Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.

One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.

Students searched for MSc Internships under the following topics: 1. Understanding temporal variability in functional biodiversity and 2. Characterization of engineered nanoparticles in aquatic organisms: Gold nanoparticles and carbon nanotubes

PhD candidate Agnes van Steen researched the history of the Leiden women’s rights movement (1860-1990) and found that the university produced many feminists.

To what extent do nanoparticles accumulate in plants and animals, and what properties of the particles play a part in this? Willie Peijnenburg, professor of Environmental toxicology and biodiversity was awarded a Marie Curie grant to conduct research on the environmental effects of nanoparticles.

Conference

The Seasons of Interdisciplinarity are an initiative by the Young Academy Leiden that started in 2021.

Overview of all dissertations published by PhD candidates from CML.

Many of our staff and students have won prizes over the past year. Others have been awarded a subsidy, or, because of their eminence in their field, they have been appointed member of an academic society or have taken on a position in the community. Reasons enough to be proud of them and to include…

Over the past year, many of our staff and students have won prizes, been awarded a substantial grant or been appointed to an academic association or a position in public life. All of these are good reasons to include them in our 2019 Hall of Fame. We are proud of them all.