210 search results for “target therapy” in the Staff website
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From the lecture hall: in conversation with an inmate
Students stream into the lecture hall, handing in their mobile phones at the door. Once everyone’s seated, silence descends and all eyes turn to the large screen at the front of the lecture hall. A live connection has been set up with the prison where Marco is a long-term inmate. Today, the students…
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Online Q&A Master Transfusion Medicine and Cellular and Tissue Therapies
Study information
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'The measurement model works, but the minister is setting reduction targets that are too high'
Opponents of drastic nitrogen measures argue that the nitrogen calculation model is not reliable enough. Nitrogen professor Jan Willem Erisman: 'It is now much more important to discuss the choices we make on the basis of the outcome. The differences are much bigger than the uncertainties in the mod…
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Inhibitors and probes targeting mannanases
PhD defence
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Inhibitors and probes targeting PslG
PhD defence
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Proof of Concept grants for four Leiden researchers
Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.
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Ruthenium-peptide conjugates for targeted phototherapy
PhD defence
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PTSD treatment can help patients with childhood trauma
Adults who were abused or mistreated as a child and consequently suffer from post-traumatic stress disorder (PTSD) can benefit greatly from cognitive behavioural therapy. This is the conclusion of a study of 149 patients. Researcher and PhD candidate Chris Hoeboer is hopeful about the results and the…
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Learning Unkown Intervention Targets in Structural Causal Models
Lecture
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Psychology Elevator Pitch: How a better sleep pattern makes students mentally healthier
Do you often find yourself exhausted in the lecture hall or at your workplace? Not great for your mental well-being, as Laura Pape knows. She is investigating how an online self-help program can assist in addressing sleep issues and preventing mental health problems. Join her on this elevator pitch…
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Antibiotic Discovery: From mechanistic studies to target ID
PhD defence
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Health insurance
If you wish, you can take part in the collective health insurance scheme offered by Leiden University and Zorg en Zekerheid. This scheme offers a collective discount, for you and your family.
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Research in the media
How can you ensure that your research hits the headlines? How can you bring your research output, such as PhD research or a publication, to the attention of the public?
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NWA grant for health law as part of NWA Cure4life
Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
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Call: collaboration between humanities and regenerative medicine
Research
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Discovery of Antibiotics and Their Targets in Multidrug-Resistant Bacteria
PhD defence
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Grant Elise Mathilde Fund & LUF: Using virus to kill bacteria: design of innovative phage-antibiotic combination treatments to combat antimicrobial
Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.
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LEF grant for Semiha Aydin to pilot social anxiety treatment
Semiha Aydin is one of the three first-generation researchers who received a grant from the Leiden Empowerment Fund to stimulate their scientific career.
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Medical Delta professor Marco van Vulpen: ‘I advocate the introduction of the share factor’
Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…
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On barriers and bridges: autoimmune rheumatic diseases and the road to a cure
Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Reportage: training anxious children should help prevent disorders and depression
Many primary school children suffer from anxiety and their numbers are increasing. Psychologists from the Knowledge Center Anxiety & Stress (KAS) are developing and researching preventive training.
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
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RARE-NL: LUMC joins consortium to find treatments for rare diseases
RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.
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Podcast: Becoming a Clinical Psychologist
Soon you will have graduated, and then what? Maybe you've been dreaming of becoming a psychologist for years, but don't want to know where to start. In this episode, clinical psychologist and lecturer Sepideh Saadat tells you how to go about it.
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
PhD defence
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image-based localization of lipid-based nanomedicines for the exploration of targeted drug delivery
PhD defence
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Binge-eating disorders in the Arab world and the Netherlands
Psychologist Bernou Melisse was shocked at the long waiting lists in the Netherlands for people with binge-eating disorders. The problem was not yet on the map in Saudi Arabia. She therefore decided to study how people suffering from binge eating can be helped better in their own region of the world.…
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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Willem van der Does sheds new light on the at times pitch-black history of psychiatry
Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…
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Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
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Cancer patients want a doctor who shows empathy and doesn’t make vague promises
Patients with incurable cancer want their oncologist to be clear but to show empathy too. They find hard and vague communication harmful. These are the results of a study by psychologists from Leiden that has been published in the American journal Cancer.
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Polypeptide Therapeutic Solutions and Universiteit Leiden Announce Collaboration to Develop Advanced Polyaminoacid Drug Delivery Systems
Polypeptide Therapeutic Solutions (PTS), a leader in the design, development and custom manufacturing of polyamino-acid based delivery systems for therapeutic drugs and the Leiden Academic Centre for Drug Research (LACDR) today announced a research collaboration to develop advanced drug delivery systems…
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300 million euros for new international stem cell consortium
The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…
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Huge advances could be made in the treatment of patients with childhood trauma
There’s a lot that goes wrong in the treatment of patients with PTSD caused by childhood trauma. Endowed professor Maartje Schoorl wants to resolve this by bringing scientific research closer to the practice. Inaugural lecture on Friday 29 April.
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Michiel van de Sande delivers inaugural lecture on advancing sarcoma care
On 5 November 2021, Professor Michiel van de Sande of the Department of Orthopedics in the Leiden University Medical Centre (LUMC) delivered his inaugural lecture ‘The Art of Doing and Doing Nothing’. Van de Sande used the opportunity to explore both physical and philosophical aspects of co-decision…
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Contributing to cancer research in your own way: three PhD candidates on their work within Oncode Accelerator
Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…
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Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
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ULLA workshop 2023 Leiden
This week, we are hosting the ULLA workshop 2023. We are proud partner of the ULLA. It is the European University Consortium for Pharmaceutical Sciences in which LACDR participates for already 30 years.
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‘Cancer treatment should be a six-week life event’
When internist Christian Blank made his very first discovery, his field of immunotherapy was the underdog of cancer research. Now, over 20 years later, Blank has been appointed Professor By Special Appointment of Internal Medicine for his clinical research into immunotherapy and will give his inaugural…
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Oh no, a mistake! Investigating the constant performance monitoring in our heads
Psychologist Myrthe Jansen conducted research into the performance monitoring that constantly takes place in our heads. People with obsessive-compulsive symptoms are more afraid to make a mistake that harms others, than when they make a mistake that only harms themselves. Jansen received her PhD on…
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Serious game helpt mensen met Niet Aangeboren Hersenletsel (NAH) opnieuw te navigeren
Om de weg te vinden letten sommige mensen op de omgeving, anderen onthouden waar ze links of rechts af moeten slaan. Mensen met Niet Aangeboren Hersenletsel (NAH) rapporteren navigatieproblemen. Om opnieuw te leren navigeren heeft neurowetenschapper Milan van der Kuil als revalidatietherapie een serious…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Special donor makes stroke recovery research possible
How do you ensure that people who have had a stroke get the right therapy at the right time? This is the question researcher Jorit Meesters wants to answer.