Vaccination is the most effective method to prevent influenza infection. However, current influenza vaccines have several limitations. Relatively long production times, limited vaccine capacity, moderate efficacy in certain populations and lack of cross-reactivity are important issues that need to be…

This project aims to explore and examine the factors that impact upon the efficacy of information disclosure duties pertaining to customer data use in online business.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The Institute of Security and Global Affairs (ISGA) of Leiden University contributed to the design and teaching of modules of this year’s edition of the Ministry of Defence’s ‘International Military Cooperation Course Africa’.

In Europe, archaeological traces of fire become more frequent between 300,000 and 400,000 years ago; but could the earliest occupants have survived without fire for at least half a million years before this? How could the early occupants of Europe have kept warm and processed meat without fire?

Social aspects of the learning environment, also called classroom climate, are important for students’ cognitive and affective learning outcomes. In this thesis the classroom climate is operationalised by means of two components: the teacher-class relationship and classroom discipline.

Article by Annemarie Samuels in History and Anthropology

This article presents a five-step framework for building behavioural cybersecurity strategy to reduce human-related risks affecting organisational security

The main question I want to answer is about the mutual influence between the cultural and settlements changes that occurred between the Bronze and the Early Iron Age in Margiana and the management of water resources.

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

In The Agency of Empire: Connections and Strategies in French Expansion (1686-1746) Elisabeth Heijmans places directors and their connections at the centre of the developments and operations of French overseas companies.

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

From ca. 1540 to 1600, thousands fled the war-stricken Southern Low Countries to the British Isles, Germany, and the Northern Low Countries. Research on this displacement crisis, central to the formation of the Netherlands and Belgium, reflects 21st-century debates on migration and language: language…

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?

Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken

The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…

This project aims to provide evidence-based knowledge on the conditions for successful anti-corruption activism in Ukraine.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

What are the key technical, social, regulatory, economic, and ethical considerations for scaling up ocean-based Carbon Dioxide Removal (CDR) approaches, and what integrated assessment frameworks and governance structures are needed to facilitate their implementation at scale?

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

On 23 June 2020, Santy Kouwagam defended her PhD-thesis 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. The doctoral research was supervised by Prof. A.W. Bedner and Prof. C.E. von Benda-Beckmann.

What is effective viewing behavior for foreign language learners and how can teachers effectively train language learners to apply effective viewing strategies that will maximize their learning when viewing subtitled materials?

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

CML report 192

In this article, Tom Buitelaar proposes a systematic framework for analyzing the impact of individual characteristics of peacekeeping leaders on the behaviour of field-level personnel in UN peacekeeping operations.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Promotores: G. Persoon, R. Schefold

On February 20th, Gulnaz Sibgatullina succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Gulnaz on this great result.

K-pop band BTS joining the Korean military is a compulsory obligation, one with increased meaning as tension builds on the Korean Peninsula and around the world, postdoc Aleydis Nissen writes in an article in The Diplomat.

China is conducting joint military exercises this week with Cambodia, Laos, Malaysia, Thailand, and Vietnam. In doing so, it is seeking to strengthen military ties with the ASEAN Member States amidst growing US presence in the region.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

On 29 January, the military administration in Myanmar sent a representative to the ASEAN Foreign Ministers’ Retreat, marking the first time that a representative from Myanmar has attended a high-level ASEAN meeting in over two years.

The question of how military interventions can best transition to a long term counter-terrorism policy forms the core research question of three interlinked reports. This research project has been completed with support of NATO’s Science for Peace and Security Programme. Leiden University researchers…

Fabio Cristiano contributed two chapters to the Routledge Companion to Global Cyber-Security Strategy, edited by Scott N. Romaniuk and Mary Manjikian.

A team led by Dr. Yannick Veilleux-Lepage (Institute of Security and Global Affairs) and Joris Larik (Leiden University College The Hague) have secured research funding from the Canadian Department of National Defence and Canadian Armed Forces funded RWE-CAF Research Network.

French title: Communication et violences dans le Guéra et le Moyen-Chari (Tchad) de 1940 à 2010. This research investigates the relationship between the introduction of new means of communication and violence experienced by the local populations in the Moyen-Chari and the Guéra regions in Chad from…

This research project addresses an unexplored dimension of historical conflict resolution: the dynamics of strategic choices made by traders engaged in foreign trade in the city of Danzig (Gdansk) c. 1450-1580, a Hanseatic city under the Polish Crown.

How did interests outside the scope of the Dutch chartered trading companies influence the career-paths of Dutch colonial governors?

Twenty years after the passing of Resolution 1325, the participation of women as military personnel in peacekeeping operations remains limited. Women currently comprise just under five per cent of military personnel in UN peacekeeping missions, and the UN consistently calls for more.