Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

This thesis is based on five papers on several topics.

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.

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This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

A research data infrastructure in computational social science

This study is a critical discourse analysis of the misogynistic narratives shared by three incel violent extremists.

Promotor: Prof.dr. E. Deprettere

Can we develop a platform for raw materials intelligence?

Are you thinking about studying Cultural Analysis: Literature and Theory? Learn more and watch the introduction video.

The master in Cultural Analysis: Literature and Theory at Leiden University studies contemporary literature and culture (art, cinema, pop music) from a theoretical, critical perspective, with special emphases on approaches developed in cultural and literary studies, feminist theory, phenomenology and…

This paper, written by Silvia D'Amato & Andrea Terlizzi, investigates the extent to which the European Union is strategically engaging against terrorism.

How does the cluster bootstrap procedure in combination with various types of linear models perform in the analysis of longitudinal data, compared to other methods.

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek

This project aims to improve understanding of, and responses to, the phenomenon of lone actors through analysis of comprehensive data on cases from across Europe.

The wealth of shoes, sandals and other footwear from ancient Egypt is poorly understood due to lack of research. This is remarkable, because from the very beginning of Egypt’s long history footwear served practical as well as more spiritual purposes.

Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

igraph development focused on improving the most-used interfaces, which are Python, R, and Mathematica. Additionally, the developers aim to make the library and the interfaces easier to maintain, focusing on long-term sustainability. This ensures that igraph continues to be a useful tool for network…

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Science, Mathematical Institute (MI)

On 1 June 2022, Bruno Braak defended his thesis entitled 'Overcoming ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019).' The doctoral research was supervised by Prof.dr. J.M. Otto, Dr.ir. C.I.M. Jacobs, and Dr. C. Leonardi…

D2.2 comprises the in-depth legal analysis of the initial heuristic model, focused on addressing, in more detail, the main legal concerns for data reusers in the European data economy. This detailed analysis of the legal propositions presented in D2.1 is supplemented by an analysis of the technological,…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

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We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

D1.2 reports on the findings of an analysis of framework conditions relevant in the context of the data economy from a legal, a socio-economic and a technological perspective. The analysis is a key foundation for the creation of an initial, heuristic model of the European data economy. The deliverable…

Thanks to data science, we can chart and search enormous quantities of related information. This generates all kinds of new insights, for example in complex global financial structures or such societal problems as loneliness.

Doctoral Thesis

Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?

Supervisor: Gerard van Westen

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

On 24 January 2024, Vethaak defended the thesis 'Empirical Analysis of Social Insurance, Work Incentives and Employment Outcomes'. The doctoral research was supervised by Koen Caminada and Pierre Koning.

In this consortium CWTS (Leiden University) collaborates with two Swedish SMEs: Monocl AB and Recorded Future AB. Monocl AB delivers intuitive analysis software to Life Sciences professionals in support of strategic decisions and improvement of business performance. Recorded Future AB is an organization…

A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…