169 search results for “hormones” in the Public website
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MeRGeR: Physiological significance of the glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
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Research
Although there has been an increase in the research into brain function and dysfunction in relation to stress and emotions, there are still many unanswered questions.
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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More JAZ in the orchestration of jasmonate-mediated plant defense
Promotor: Prof.dr. J. Memelink
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Lab facilities Clinical Neurodevelopmental Studies
Neurobiological, cognitive and behavioural measurements of normal and abnormal child development.
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Development & Disease
Development & Disease is one of the four research themes of the Institute of Biology Leiden.
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Blended Care for Adolescents with Social Anxiety
Is blended care a feasible and effective treatment method for social anxiety in adolescence?
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Marcel Schaaf
Science
m.j.m.schaaf@biology.leidenuniv.nl | +31 71 527 4975
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ERC Consolidator Grants for six Leiden researchers
From the effects of hormone fluctuations in women via the interior structure of giant planets to the prehistory of the languages: six Leiden researchers have been awarded a Consolidator Grant by the European Research Council.
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More efficient learning thanks to sleep
Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.
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Kinetics for Drug Discovery: a Case for the Adenosine A3 receptor
Supervisor: Lizi Xia
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Medicine
The Faculty of Medicine
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COMMUNITY: unraveling the regulatory networks in Streptomyces that switch on antibiotic production on demand
Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics
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Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
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Covalent inhibitors of G protein-coupled receptors: the case of adenosine receptors
Supervisor: Xue Yang
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Plant Sciences
The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…
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Plant-microbe interactions
Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?
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About the programme
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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Pavlov revisited. About the placebo effect of rose scent
Health psychologist Aleksandrina Skvortsova has made clever use of the Pavlov effect to link the ‘cuddle’ hormone oxytocin with the placebo effect. This effect can alter the level of oxytocin in the body, making it possible for people to reduce the amount of medicine they need while still feeling good.…
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Participants
The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).
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Education and Child Studies
How do people develop and how do they learn? How does their environment affect them? How do we ensure that they develop in optimal fashion? And what can we do if problems occur? These are questions that the researchers at the Institute of Education and Child Studies try to answer.
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Group behaviour: one for the team
Researchers at Leiden study group behaviour. One of their findings is that when people make sacrifices for another member of their group, it is probably instinctive. Insights of this kind enable us to better understand and influence the social processes in a neighbourhood or company.
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What to focus on for a clean environment?
The earth has more than 7 billion inhabitants, all of whom leave behind traces of pollution. However, not all forms of pollution have the same harmful effect. Leiden scientists help determine where we should put our priorities.
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Research
The researchers at the Institute of Education and Child Studies focus on child rearing and the development of children and adolescents with and without developmental and other problems, in biological and non-biological families, childcare, education and care institutions.
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Stem cells as cure
Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.
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Tracking genes to fight breast cancer
PhD student Esmee Koedoot studied the underlying processes responsible for metastases in a dangerous type of breast cancer. She hopes to find new possibilities to fight the disease. In December 2019 she obtained her doctorate cum laude.
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How oxygen deprivation causes cancer cells to spread
In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…
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NWO grants two IBL-proposals by interdisciplinary research consortia
Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.
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What happens to the brain when you become a mother?
May 12 is Mother's Day in many countries. Becoming a mother is no mean feat: brain scientist Elseline Hoekzema has shown that a woman's brain changes drastically during pregnancy. She explained how in TV show De Kennis van Nu.
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Brain research shows punishing is more rewarding than helping
Just imagine: you see someone being treated unfairly. Do you find it more rewarding to help the victim or punish the perpetrator? Research by Leiden psychologist Mirre Stallen indicates that punishing is more rewarding. Publication in JNeurosci.
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‘It’s a real balancing act for doctors at gender clinics’
Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.
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Not words, but data: guidance on healthcare dilemmas for transgender young people
There are differing opinions about healthcare for transgender young people. Lieke Vrouenraets investigated the ethical dilemmas.
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Butterflies’ wing patterns change with the seasons
Tropical butterflies adapt to their environment to improve their chances of survival. The changes are triggered by hormone signals that transmit information about temperature to the butterflies' tissues. Biologist Ana Rita Mateus shows how a complex combination of environment, physiology and genetics…
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What plant genes can teach us
Just like us, plants also produce growth hormones, and they also go through an ageing process. The study of the genes and mechanisms behind these processes is useful not only for crop breeding and agriculture, but also for medical research. That is the view held by Professor of Plant Developmental Genetics…
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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Four Vici grants for Leiden University researchers
Four researchers from Leiden University have been awarded prestigious Vici grants the Dutch Research Council (NWO) has announced. The honoured applications are from researchers at the Faculty of Social and Behavioural Sciences, Leiden Observatory, the LUMC and the Faculty of Archaeology.
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Psychology Connected over gender differences: 'More research done on extraterrestrial life than the female body'
In medical and psychological sciences, little research has been specifically conducted on women. Hormonal fluctuations were considered too intricate. Yes, research into sex and gender differences is complex, acknowledge neuroscientists Ellen de Bruijn and Lara Wierenga, but that’s precisely why it's…
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Pregnancy changes brain structure
Brain researcher Elseline Hoekzema has discovered that the structure of the brain changes during pregnancy, particularly those areas related to social functions. These changes persist for at least two years after the mother gives birth. Publication in Nature Neuroscience on 19 December.
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Elseline Hoekzema investigates the impact of pregnancy on the human brain with European grant
Neuroscientist Elseline Hoekzema receives a large European grant from the European Research Council (ERC). This ERC starting grant for promising young researchers allows her to investigate the effects of pregnancy on the brain in detail.
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The parallels between quarrelling animals and humans
The journal Philosophical Transactions of the Royal Society – Biological Sciences published its theme issue ‘Conflict across taxa’ on 4 April, which was edited by Professor of Social and Organisational Psychology Carsten de Dreu. Together with researchers from other disciplines he provides more insight…
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‘Unimportant’ plant gene turns out to be essential
Leiden biologists have shown that a gene present in plants, animals and yeasts does play an important role in plants, although for years the gene was considered unimportant. It turns out the gene plays a crucial role in the development of vascular tissue in plants. Publication in Nature Plants on 11…
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Why stress could be good for you
Acute stress seems to have a surprisingly positive effect on our health. Researcher Erin Faught received an NWO veni grant to find out why that is and how we can use that knowledge to our advantage. For her lab research, she uses a remarkable small animal to learn more about our own stress levels.
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Health psychologist Jos Brosschot professor by special appointment
Jos F. Brosschot has been appointed as a professor by special appointment on the chair ‘psychophysiological mechanisms of stress in daily life’. This chair has been created by the Foundation for Research into Psychosocial Stress.
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Greed and fear hamper cooperation
Everyone benefits when cooperation runs smoothly However, people often act obstructively. Why do they do that? Professor of Social Psychology Carsten de Dreu researches this issue using a wide variety of methods, from brain scans to the role of religion. Inaugural lecture 7 October.
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Remko Offringa appointed Professor in the field of Plant Developmental Genetics
Remko Offringa has been appointed Professor in the field of Plant Developmental Genetics within the Faculty of Science at the Institute of Biology Leiden (IBL) from the 1st of April 2017. Offringa’s research focuses on the role of the plant hormone auxin in controlling plant growth and development,…
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Zebrafish personality, stress physiology and behaviour in the context of sound exposure
To what extent is sound a stressor to fish? And are behavioural and physiological phenotypes equally sensitive to disturbance by noise pollution?
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Topic: Self-management in chronic diseases
Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…
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Inverse Agonism and Constitutive Activity
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