258 search results for “high been dettje” in the Public website
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Microfluidics for high-throughput liposome formulation for personalized cancer vaccination
Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…
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Learning-based Representations of High-dimensional CAE Models for Automotive Design Optimization
In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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Policing the high seas: maritime law-enforcement in a multi-actor environment
Identifying the gaps in the legal framework for EU activities in the maritime security domain, and specifically in the areas of combating piracy, human smuggling or trafficking and drug trafficking.
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Néron models in high dimension: nodal curves, Jacobians and tame base change
We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.
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Radio galaxies at low frequencies: high spatial and spectral resolution studies with LOFAR
Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley
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It's just a phase: High-contrast imaging with patterned liquid-crystal phase plates to facilitate characterization of exoplanets
This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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Causal Discovery from High-Dimensional Data in the Large-Sample Limit
Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets
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modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.
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efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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revealing the operation of AGNs in galaxy clusters with high-resolution radio observations
Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.
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Paving the path between low- and high-mass star formation: dynamics probed by Herschel far-infrared spectroscopy
Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)
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The High Representative in Bosnia-Herzegovina: The Unusual Institutional Arrangement of a Non-Authoritarian, Yet Controlled, Democracy
In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, argue that Bosnia-Herzegovina survives so far on the basis of negative legitimacy.
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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machine learning algorithm for prediction and generation of High-Energy Physics data
Assistant Professor Vedran Dunjko and his team received a gift from Google to support their quantum research. The research focuses on whether quantum computers can provide new ways of understanding the mysteries of high-energy physics.
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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laissez-faire politics. Public discourses on political authorities in high-trust countries during the COVID-19 pandemic
This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.
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simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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Hai Lin
Science
h.x.lin@cml.leidenuniv.nl | +31 71 527 7460
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Kristian Rietveld
Science
k.f.d.rietveld@liacs.leidenuniv.nl | +31 71 527 7038
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Activated Reaction of Polyatomic Molecules on Surfaces Using a High-Dimensional Neural Network Potential: CHD3 + Cu(111)
An accurate description of reactive scattering of molecules on metal surfaces often requires the modeling of energy transfer between the molecule and the surface phonons. Although ab initio molecular dynamics (AIMD) can describe this energy transfer, AIMD is at present untractable for reactions with…
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Pain relief without the high
Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.
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Jaap Reijling
Faculty Governance and Global Affairs
j.reijling@fgga.leidenuniv.nl | +31 70 800 9400
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Simon Portegies Zwart
Science
spz@strw.leidenuniv.nl | +31 71 527 8429
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Strikes the result of high inflation
Employees are laying down their work in various sectors, such as regional public transportation and Dutch postal service PostNL. Inflation appears to be increasing dissatisfaction about working conditions, thinks Barend Barentsen, Professor in Labour Law at Leiden University. ‘It's the final straw.’
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Paradox in superconductivity at high temperature
Nature publishes an article on a paradoxical discovery in superconductivity. Physicists are searching for superconductivity at high temperatures so that less cooling is needed in for example MRI machines. News & Views article by Prof. Jan Zaanen in the same issue of August 19th.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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HEPGAME
HEPGAME is a research project that combines the world’s fastest computer algebra system for High Energy Physics equations, FORM, with insights from artificial intelligence. The name combines High Energy Physics and Games.
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Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
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New theory on liquid crystals with high symmetry
LCD screens use liquid crystals which have a high degree of order, even though they form a fluid. A new theory maps out the interplay between order, temperature and symmetry. Publication in Physical Review X.
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Barend Mons appointed Chair of European Commission’s High Level Expert Group
Professor Barend Mons has been appointed Chair of the Commission High Level Expert Group
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Bas ter Braak
Science
s.j.ter.braak@lacdr.leidenuniv.nl | +31 71 527 2727
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Thomas Hankemeier
Science
hankemeier@lacdr.leidenuniv.nl | +31 71 527 4226
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What are the ingredients of high performing district teams?
Since the decentralizations in the social domain in 2015, nearly all Dutch municipalities use district teams to organize care. However, the management, organization and composition of these district teams vary considerably between municipalities: each municipality tries to reinvent the wheel by itself.…
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Slovenian and Czech high school students visit Leiden University
Sixty-four high school students from Slovenia, Czech Republic and The Netherlands have visited Leiden University in the week of 7-11 November, as part of the Talent Education Project. They split in eight groups, of which some went to the science faculty to conduct research projects.
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Strings attached to future high-temperature superconductivity
The behaviour of strongly correlated electron systems, such as high-temperature superconductors, defies explanation in the language of ordinary quantum theory. A seemingly unrelated area of physics, string theory, might give physicists a better understanding of the weird behaviour of these kinds of…
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First discovery of high-energy neutrino source
For the first time, scientists have traced back a high-energy neutrino to its source in space. It was produced by a so-called blazar—a supermassive black hole. Researchers from neutrino detector IceCube report this in Science. ‘This is a milestone for neutrino science,’ says physicist Dorothea Samtleben…
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‘High price for British trade treaty with US’
The British government' is expecting too much of American support after Brexit: there will be a high price to pay for any trade treaty with the United States. This was the view expressed by assistant professor Joris Larik in Dutch newspaper De Volkskrant today, following the visit of American President…
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Leiden Humanities ranks high in QS World University Ranking
Humanities Faculty Leiden occupies a 49th place in the field of Arts & Humanities in the QS World University Ranking. Especially the subject areas Linguistics and History & Archeology rank high, with respectively a 26th and 28th place. Leiden University has fallen by one place in the annual QS World…
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History and Classics rank high in QS Rankings by Subject
Leidens's Classics and History rank 6th and 15th place in the QS World University Rankings by Subject. Every year, QS ranks universities all over the world on academic reputation and research impact, grouped by subject. Linguistics (23), Languages (39) and Religious Studies (40) also do well in the…
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Isotopes and the characterization of extrasolar planets
Diverse types of exoplanets such as gas giants on close-in orbits (hot Jupiters) and young massive giants on wide orbits (super Jupiters), with no analogs in the Solar System, pose challenges but also opportunities to our understanding of planet formation and evolution.
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Subsidies for high-grade research facilities
Three projects with Leiden researchers are to receive a subsidy from NWO for the construction or renovation of large-scale research facilities. They will be working on electron microscopy, an X-omics initiative and an X-ray telescope. The projects are part of the National Roadmap for Large-Scale Scientific…
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How EU farm subsidies favour high-emission animal products
More than 80 percent of the EU’s agricultural subsidies go to the production of animals or animal feed. These products are responsible for 84 percent of the EU’s food-related greenhouse gas emissions. That is revealed in a new study by three Leiden researchers published in Nature Food. ‘If we continue…
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Flying visit by high-ranking Chinese delegation
A high-ranking delegation from China visited Leiden on 6 November. The party of some 25 officials from the CPPCC – a Chinese advisory body comparable with the Dutch Senate - visited the Leiden Observatory, the Hortus Botanicus and the Asian Library.
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Inaugural lecture: X-ray diagnostics in space: Lines in the universe
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High level appointment for EIBL alumnus Martin Richardson
Martin Richardson, who graduated in 1997 from what was then the Leiden LLM Programme in European Community Law (now: Leiden Adv LLM European and International Business Law, EIBL), has recently been appointed as a Senator of the College of Justice in Scotland, meaning that he is now a judge of the highest…
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David Doelman
Science
doelman@strw.leidenuniv.nl | +31 71 527 2727