Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

September 26 is the European Day of Languages. There are 24 official languages in Europe but some 200 languages in total are spoken on our continent. What good are all these different languages? And should we all learn Azerbaijani or Swedish? We asked Lisa Cheng, Professor of General Linguistics.

The LUCL has a new Scientific Director. Professor Sjef Barbiers took over the reins from Lisa Cheng with effect from 1 January. 'This is a great opportunity to contribute to a wonderful institution.'

Fiffy the chimpanzee had rapidly developed cataracts in both eyes that made her as good as blind. Eye doctors at the Leiden University Medical Center (LUMC) have now managed to replace the lenses in both her eyes. As far as we know, Fiffy, who is thought to be between 30 and 40 years old, is the first…

He had been emeritus for 13 years when he suddenly received an email from Poland. Professor of Inorganic Chemistry Jan Reedijk was awarded an honorary doctorate from Nicolaus Copernicus University in Toruń. During the celebration of the 550th anniversary of the birth of patron Nicolaus Copernicus,…

Professor Marc Koper researches how you can use electrical energy to make or break chemical bonds. He has just been awarded a Spinoza Prize, the Netherlands’ highest personal science award, for his fundamental research into how this form of electrolysis works.

Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…

Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

James Webb life’s building blocks

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

At the beginning of the corona pandemic, our Faculty appointed student mentors to guide first-year and international students. What drives these mentors, and what is it like to be back at the Faculty again? Mireia and Marten tell us all about it.

Halfway through his career alumnus Marc Tijhuis made a radical change: he left the corporate world to join the global battle against waste with the International Solid Waste Association.

Gianne Derks is the MI’s new scientific director from 1 May. She has worked abroad longer than in the Netherlands and, after more than 27 years in Surrey, she dreams in English. Who is this new director and who or what managed to entice her to make the move to Leiden?

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…

Organisation

Claartje Levelt is professor of First Language Acquisition. She researches how babies and toddlers learn their mother tongue. Besides her work, she enjoys being involved with music.

Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.

PhD

The South African poet and author Antjie Krog gave the 37th Albert Verwey Lecture in the Great Auditorium in the Academy Building on 18 November. Inspired by Verwey’s poem ‘De zegger van verzen’, Krog’s lecture was a polyphonic and multilingual love letter to poetry.

Laurens Hessels was appointed Professor by Special Appointment, lecturing in the Social Value of Science at Leiden University, effective 1 September 2021. His research will focus how best science and industry can work together. Alongside his new position he will continue his work at the Rathenau Institute…

Europe's latest quantum computer is set to arrive in the Netherlands. The Dutch IT cooperative, SURF, which supports education and research institutions, has secured funding from the European EuroHPC programme to make this possible. Researchers from Leiden University will play a key role in the project,…

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

On Saturday 16 April, secondary school pupils will once again have a chance to sink their teeth into the hardest language-related questions during the final of the Linguistics Olympiad. Professor Sasha Lubotsky and PhD student Cid Swanenvleugel are both former Olympiad winners. Now they are involved…

Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…

An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.

Last year around 2,000 international students started a master’s degree at Leiden University. To make this possible, there are various grants that these students can apply for. One such grant is the LExS: the Leiden University Excellence Scholarship Programme. Three LExS students tell us about their…

Cramming from a book, making notes or learning summaries. In the past these were about the only ways to memorise your course material. But that has long since changed. Multimedia is the code word. But is it effective?

Three Leiden professors have recently been awarded the most prestigious scientific accolade in the Netherlands: Maria Yazdanbakhsh and Marc Koper have been awarded a Spinoza Prize and Judi Mesman a Stevin Prize. They received their prizes on 13 October.

Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.

‘It was the biggest bunch of flowers I’d ever seen,’ says Emily Strange about the moment she won the Leiden Teaching Prize 2022. The judge praised the conservation biologist for her passion, engaging personality, and the way she motivates her students. On the Dutch Day of the Teacher, we get to know…

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

Jasper Knoester is the dean of the Faculty of Science. How is he doing? What kinds of things is he doing and what does his day look like? In each newsletter Jasper gives a peek into his life as dean.

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…

Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.

For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…

Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…

Matthias Flór receives the KHMW Graduation Prize in Theoretical Physics for his master's thesis. His research on exotic superconductors at Leiden University and TU Delft struck a chord with the jury. The jury unanimously chose to award Flór noting that ‘he demonstrated impressive technical abilities…

The European Research Council (ERC) has awarded an Advanced Grant to six Leiden researchers. It awards these significant grants to established principal investigators for ground-breaking, high-risk research.