1,106 search results for “carlo electron microscopy cryo-em” in the Public website
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Low energy electron transmission through layered materials and chiral organic films
In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…
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Lasers, lenses and light curves: adaptive optics microscopy and peculiar transiting exoplanets
Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen
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Carlos Roos Muñoz
Faculty of Humanities
c.m.roos.munoz@hum.leidenuniv.nl | +31 71 527 2727
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A new method to reconstruct the structure from crystal images
Promotor: J.P. Abrahams, Co-promotor: T. Grüne
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Molecular electronics: Controlled manipulation, noise and graphene architecture
Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.
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Carlos Siguenza Sanchez
Science
c.p.siguenza.sanchez@cml.leidenuniv.nl | +31 71 527 2727
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Inaugural lecture: Big pictures of small microbes
Bacteria are everywhere. They are the most abundant organisms on earth and impact all aspects of our lives. They determine our health and shape our environment. Ariane Briegel, professor of Ultrastructural Biology, freezes bacteria super fast to gain a true-to-nature image of the internal and external…
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Carlos Campello Pereira Porto Soares
Faculty of Humanities
c.e.campello.pereira.porto.soares@hum.leidenuniv.nl | +31 71 527 2727
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The confrontation between voice and electronics
The principal aim of this research is to explore the confrontation between voice and electronics. These are often seen as being radically different from one another and many characteristics seem to be in opposition between them. However, they also have characteristics in common and they can influence…
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New transmission microscope for low-energy electrons
Physicist Daniël Geelen has developed a new microscope that uses low-energy electrons. Those are less harmful to biological and organic materials. Geelen defends his PhD thesis on May 31st.
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Meindert Lamers
Science
m.h.lamers@biology.leidenuniv.nl | +31 71 527 2727
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Electronic spectroscopy of molecules of astrophysical interest
This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).
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Carlos Felipe Blanco Rocha
Science
c.f.blanco@cml.leidenuniv.nl | +31 71 527 4371
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Postdoc: Reactive scattering with electronic friction
Science, Leiden Institute of Chemistry (LIC)
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New book on history electron microscopy including Leiden Physics
On February 2nd the book Beelden zonder weerga appears, written by professor in science history Dirk van Delft and biochemist Ton van Helvoort. They describe the rich history of electron microscopy, which comes to a conclusion in the final chapter with the current state-of-the-art ESCHER microscope…
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On electronic signatures of topological superconductivity
Promotor: Prof.dr. C.W.J. Beenakker
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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COMPOSING FOR ORGAN AND ELECTRONICS: SPACES AND PRACTICES
My research focusses on site-specific compositional and performance practices of music for organ and electronics and their musical-spatial values.
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Resolution of electron microscope greatly improved
The use of a new type of detector has generated a strong improvement in the resolution of electron microscopes. The 'low-energy electron microscope' (LEEM) can now be used for research on the thinnest possible materials. The tests with the detector represent the first result of the ESCHER project.
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PhD: Targeting electron transport chain in Listeria monocytogenes for novel antibiotic development
Science, Leiden Institute of Chemistry (LIC)
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Promoting reading skills through electronic books for grade 1 students
What is the effect of practicing with electronic books on reading skills for grade 1 students?
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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The symmetry of crystals and the topology of electrons
Promotor: J. Zaanen, Co-Promotor: V. Juricic
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formation and growth by nanoparticle tracking analysis and flow imaging microscopy
The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.
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Fluorescence Correlation Spectroscopy on Electron Transfer Reaction: Probing Inter- and Intramolecular Redox Processes
Promotores: G.W. Canters, T.J. Aartsma
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Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Crystal Cave
X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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y la armada de los Países Bajos durante los reinados de Felipe I y Carlos V
This book investigates how the rulers of the Habsburg world empire developed and implemented a central maritime policy for the Netherlands and appointed an admiral of the sea or admiral-general for that purpose.
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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Irene Groot
Science
i.m.n.groot@lic.leidenuniv.nl | +31 71 527 7361
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Self-assembly of flexible and rigid structures: from colloidal molecules to lattices
Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…
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Inverse electron demand Diels-Alder pyridazine elimination: synthetic tools for chemical immunology
The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…
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Melting of frozen electrons visualized
For the first time, physicists have visualized the ‘melting’ of electrons inside a special class of insulators. It allows electrons to move freely and turns the insulator into a metal and possibly later into a superconductor. Publication in Nature Physics.
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The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
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Microbial Chemotaxis
In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Single molecules show promise to optically detect single electrons
Optical detection of a single electron using a single molecule has never been done. Leiden physicist Michel Orrit and his team have now identified a molecule that is sensitive enough to detect an electron at a distance of hundreds of nanometers. The results are published as a cover article in ChemPh…
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Identification of productive and futile encounters in an electron transfer protein complex
PNAS publication on protein encounter complexes
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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Carlo Beenakker receives honorary doctorate in Kiev
Leiden physicist Carlo Beenakker has received an honorary doctorate from the Bogoliubov Institute for theoretical physics in Kiev.
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Physicist Sense Jan van der Molen plays ‘Dutch shuffleboard’ with electrons
Physicist Sense Jan van der Molen researches materials that do not exist in nature. ‘It’s fascinating to see how the properties of a material change if we manage to make it super thin.’ He will give his inaugural lecture on 21 October.
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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ERC Advanced Grant for Carlo Beenakker to ‘braid’ Majorana fermions
Theoretical physicist Carlo Beenakker has been awarded a €2m Advanced Grant by the European Research Council (ERC). He will use this to try to create the ideal building blocks for a quantum computer: ‘braided’ Majorana fermions. An ambitious project that may just lead to a major breakthrough.
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Electrons found to flow like water
Science Magazine has published three back-to-back papers on an important discovery in solid state physics. Leiden physicist Jan Zaanen wrote a Perspective article on the subject in the same issue of 4 March.