1,140 search results for “care electron microscopy cryo-em” in the Public website
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Postdoc: Reactive scattering with electronic friction
Science, Leiden Institute of Chemistry (LIC)
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New book on history electron microscopy including Leiden Physics
On February 2nd the book Beelden zonder weerga appears, written by professor in science history Dirk van Delft and biochemist Ton van Helvoort. They describe the rich history of electron microscopy, which comes to a conclusion in the final chapter with the current state-of-the-art ESCHER microscope…
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On electronic signatures of topological superconductivity
Promotor: Prof.dr. C.W.J. Beenakker
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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Resolution of electron microscope greatly improved
The use of a new type of detector has generated a strong improvement in the resolution of electron microscopes. The 'low-energy electron microscope' (LEEM) can now be used for research on the thinnest possible materials. The tests with the detector represent the first result of the ESCHER project.
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COMPOSING FOR ORGAN AND ELECTRONICS: SPACES AND PRACTICES
My research focusses on site-specific compositional and performance practices of music for organ and electronics and their musical-spatial values.
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Promoting reading skills through electronic books for grade 1 students
What is the effect of practicing with electronic books on reading skills for grade 1 students?
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Search for mechanisms to control massless electrons in graphene
Beenakker
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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The symmetry of crystals and the topology of electrons
Promotor: J. Zaanen, Co-Promotor: V. Juricic
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formation and growth by nanoparticle tracking analysis and flow imaging microscopy
The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.
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Fluorescence Correlation Spectroscopy on Electron Transfer Reaction: Probing Inter- and Intramolecular Redox Processes
Promotores: G.W. Canters, T.J. Aartsma
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Solid State NMR and modelling of photoinduced energy and electron transfer
Huub de Groot is professor in Biophysical Organic Chemistry. With his team he works in the field of photosynthesis and artificial photosynthesis. The molecular basis for photosynthesis is formed by protein complexes and organelles that contain chlorophyll molecules. The antenna systems herein capture…
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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Child care
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The development of children in foster care
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Crystal Cave
X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Narrative Navigation: HIV and (Good) Care in Aceh, Indonesia
In this article, Samuels elaborates the concept of narrative navigation to analyze the subjective and intersubjective ways in which people struggle through experiences of illness by constructing multiple, ambiguous and non-linear narratives that may continuously change, as they reposition themselves…
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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Analist 'Super-resolution microscopy & cell culture' (0.8 - 1.0)
Science, Leiden Institute of Chemistry (LIC)
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The participation of children in youth care
In this study the central question to be answered is whether children are able to participate in decisions and at which moments these decisions are taken in the youth care trajectory.
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Irene Groot
Science
i.m.n.groot@lic.leidenuniv.nl | +31 71 527 7361
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Mental Health Care Psychology
In the Dutch healthcare system, only MHC psychologists (GZ-psychologen) are licensed to practice psychology unsupervised.
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Inverse electron demand Diels-Alder pyridazine elimination: synthetic tools for chemical immunology
The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…
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LA cuidadora: Latin American female migration and elderly home-care work in Europe
Through a lens that examines the intersection of ageing, gender, class, and migration, this project addresses the 'care deficit' in European countries and the employment of migrant women from Latin America to fill this deficit.
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Parenting, Child Care and Development
The programme group Parenting, Child Care and Development studies how parents and other educators affect children's development, well-being and health. The emphasis is on the child's social, emotional and cognitive development and prevention of problems in these areas.
- Consular Diplomacy / Duty of Care
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Melting of frozen electrons visualized
For the first time, physicists have visualized the ‘melting’ of electrons inside a special class of insulators. It allows electrons to move freely and turns the insulator into a metal and possibly later into a superconductor. Publication in Nature Physics.
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Globalizing Palliative Care? A Multi-sited Ethnographic Study
This project investigates the globalization and cultural mediation of palliative care practices, policies and discourses.
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The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
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Microbial Chemotaxis
In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Single molecules show promise to optically detect single electrons
Optical detection of a single electron using a single molecule has never been done. Leiden physicist Michel Orrit and his team have now identified a molecule that is sensitive enough to detect an electron at a distance of hundreds of nanometers. The results are published as a cover article in ChemPh…
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Research
Central elements in the research activities of all programme group members are: attachment, sensitive caregiving, and prevention and intervention.
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Identification of productive and futile encounters in an electron transfer protein complex
PNAS publication on protein encounter complexes
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Blended Care for Adolescents with Social Anxiety
Is blended care a feasible and effective treatment method for social anxiety in adolescence?
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Innovation in treatment and care
Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…
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Taking care of your health
Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…
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Research
The Forensic Family and Youth Care Studies research group conducts innovative high-quality research aiming to gain knowledge about deviant developmental trajectories of vulnerable children, adolescents, and families, about how to prevent problematic development and how to intervene when necessary.
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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De Kattekop Day Care Centre
Wassenaarseweg 8, Leiden
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Education
The programme group Parenting, Child Care and Development carries out general courses within the field of Education and Child Studies and specialised courses within the field of Child and Family Science.
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Standardising care of the dying: An ethnographic analysis of the Liverpool Care Pathway in England and the Netherlands
The article 'Standardising care of the dying: An ethnographic analysis of the Liverpool Care Pathway in England and the Netherlands' by Erica Borgstrom and Natashe Lemos Dekker is published in Sociology of Health & Illness.
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Physicist Sense Jan van der Molen plays ‘Dutch shuffleboard’ with electrons
Physicist Sense Jan van der Molen researches materials that do not exist in nature. ‘It’s fascinating to see how the properties of a material change if we manage to make it super thin.’ He will give his inaugural lecture on 21 October.
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Van Marum Colloquium: Concerted Cation-Electron Transfer at Pt(111)/Perfluoro-Sulfonic Acid Ionomer Interface
Lecture