183 search results for “cancer immunotherapie” in the Staff website
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Regulation of signal transduction pathways by hypoxia in breast cancer subtypes
PhD defence
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Cancer-induced somatic mutations in G protein-coupled receptors
PhD defence
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BRCA1-associated breast cancer: finding new weapons for an old villain
PhD defence
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Patient-derived models of breast cancer: A breakthrough story of the duct
PhD defence
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
PhD defence
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Multifaceted Roles of Grainyhead-like Transcription Factor- 2 in Breast Cancer
PhD defence
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Leiden University honours Lex van der Eb with University Medal
Leiden University has awarded its prestigious University Medal to Emeritus Professor Lex van der Eb. As a pioneer in genetics and molecular biology, he received this honour for his services to science and his key role in the development of the Leiden Bio Science Park (LBSP).
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Medical Delta professor Marco van Vulpen: ‘I advocate the introduction of the share factor’
Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Review on “Anticancer opportunities at every stage of chemokine function” is featured on the cover of TIPS
Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…
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Sexuality in the consulting room embarrasses oncologists
Cancer treatments often have an impact on people’s sexual health, but doctors and nurses do not discuss topics such as sexuality and intimacy with patients as a matter of course. This is what Esmée Krouwel, a physician-researcher at Leiden University Medical Center (LUMC), has discovered. With her research…
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New potential drug suppresses chemotherapy induced neuropathic pain
Oncode Investigator Mario van der Stelt and his colleagues have discovered a new potential drug that suppresses chemotherapy induced neuropathic pain.
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KWF funding for research on culturally sensitive palliative care
The research project 'when patients don't want to know everything: guide and training for culturally sensitive information in palliative care' investigates how healthcare providers can offer inclusive palliative care.
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Klara Beslmüller
Science
k.beslmuller@lacdr.leidenuniv.nl | 071 5272727
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University flag travels to Mount Everest and back again
Leiden PhD candidate Mona Shahab climbed Mount Everest two years ago to raise money for the education of disadvantaged children in Egypt. She made it to the top and posed there with the University flag. She recently presented the flag to Rector Carel Stolker.
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Silver and light: a powerful combination with the potential to save lives
Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…
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Using health data for scientific research isn’t that simple
While health data is essential for scientific research, that data also needs to be protected. In her doctoral thesis, Irith Kist found a balance between protecting the individual and exchanging health data.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Leiden technology research receives funding from NWO and businesses
A CT scanner to treat eye cancer, energy-efficient software for the future and a test to identify male chick eggs. Three projects by researchers from Leiden University are to receive funding from research funder NWO’s Open Technology programme, to which the business sector also contributes.
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Anja Rüten-Budde wins the C.J. Kok Jury Award for best thesis
Statistician Anja Rüten-Budde has won the C.J. Kok Jury Award 2020. Her PhD thesis resulted in an app which helps patients with soft tissue sarcoma and their doctors to make well-considered choices about the treatment. ‘Her work is interdisciplinary and directly relevant for society,’ the jury state…
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Proof of Concept grants for four Leiden researchers
Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.
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Who are the winners of the Psychology Prizes of 2024?
Psychology teacher of the year is Evelien Broekhof. The Master Thesis Awards are for Yanna Naeije and Arian Memarpouri. Mirjam Wever wins the PhD Paper Prize; Jip Aarts wins the PhD Wild Card: Academic Citizenship. Congratulations!
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New Year's Reception 2025: the power of diversity and collaboration
‘Let us not forget the power of genuine engagement,’ dean Sarah de Rijcke stressed at the New Year's Reception on 7 January 2025, which was also attended by Rector Magnificus Hester Bijl and addressed the Faculty of Social Sciences.
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“You look well,” said the oncologist, but she didn't feel that way at all
Leiden psychologists Janine Westendorp and Liesbeth van Vliet have investigated types of communication that seriously ill patients may experience as harmful. The results of this research were published in the American journal Cancer. And the results have now also been published as a poster for education…
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Four Leiden researchers awarded Rubicon grants
Four promising young researchers will be able to conduct two years of research at a university abroad thanks to a Rubicon grant from the Dutch Research Council (NWO). The Leiden laureates are Renske Janssen, Girija Josh, Anne van der Meij and Yana van der Weegen.
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Statistics for the benefit of the patient
Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…
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In memoriam: Juan José Jaime Aloísio Archidona Ramírez (1992 - 2024)
On Monday 26 February the terrible news reached us that our gifted former Egyptology student – and former student assistant at the Leids Papyrologisch Instituut – Juan Archidona Ramírez had succumbed to cancer.
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New professor Suzan Verberne aims to bring large language models and search engines closer together
Suzan Verberne has been appointed professor of Natural Language Processing at the Leiden Institute of Advanced Computer Science (LIACS) from 1 October. Verberne has been at LIACS since 2017 as group leader of the Text Mining and Retrieval group.
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Mick van Schaick
Science
m.van.schaick@lacdr.leidenuniv.nl | 071 5272727
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Yvette van der Linden
Faculteit Geneeskunde
ymvanderlinden@lumc.nl | 071 5261926
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Jannie Keyser-Borst
Faculteit Geneeskunde
j.g.borst@lumc.nl |
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Ine Tijdens
Science
tijdens@lacdr.leidenuniv.nl | +31 6 2785 2348
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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PhD-Postdoc event 2022
Last October, we organized our annual PhD-Postdoc event at Kasteel Oud-Poelgeest. An important part of the program was a speed dating session with LACDR alumni.
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Language that comforts: The power of communication in healthcare
For people who are seriously ill, an empathetic doctor can make a world of difference. Psychologist Janine Westendorp examined helpful and harmful communication in the consulting room. ‘It’s very important to stress that you are always there supporting the person, even if there’s no cure.’
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Eight professors receive double appointment simultaneously
Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…
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‘I am curious and full of passion for understanding molecular chemistry’
Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…
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‘Pharmacogenetics will become part of patient care’
Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’
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Four NWO Open Competition grants for Leiden researchers
Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.
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How ‘sleeping’ microorganisms can determine the fate of a population
Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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Researchers discover how malaria parasite survives in mosquitoes
Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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Interdisciplinary Collaboration Explores Substance P in Health and Disease
A team of LACDR scientists from three different divisions (SPP, BT, MC) contributed to a book on "Substance P in Health and Disease," which will be published by Elsevier. The project was a collaboration with Hannover Medical School (Germany) and was coordinated by Alireza Mashaghi. Master students Ehsan…