Can cyclic peptides provide a new generation of antibiotics?

Research in Leiden University’s Institute of Political Science focuses on the dynamics and the interaction of political institutions, individual decision-making, and collective behaviour.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

To what extent is sound a stressor to fish? And are behavioural and physiological phenotypes equally sensitive to disturbance by noise pollution?

Overkleeft

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

Leiden University social scientists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

FAIRDOM consortium is an open initiative of various partners including funding programmes, large-consortia, institutes, small groups as well as individuals.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

A warm welcome to the Graduate School of Social and Behavioural Sciences at Leiden University.

Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink

The research group Organizational & Entrepreneurial Behavior investigates the behavior of individuals and groups who start, work in, or lead organizations, in order to inform organizational practice. By focusing on the behavior of (groups of) employees, entrepreneurs and leaders, the main levels of…

Our current lifestyle is not sustainable, and we know it. Our carbon-based economy causes climate change, and our livestock threatens the rainforests. We also know what we ought to do to save the planet: decarbonize the economy and change our diet. However, too many people lack the moral motivation…

Researchers at Leiden study group behaviour. One of their findings is that when people make sacrifices for another member of their group, it is probably instinctive. Insights of this kind enable us to better understand and influence the social processes in a neighbourhood or company.

A Study of Middle Palaeolithic Riverside Settlements at Maastricht-Belvédère (The Netherlands).

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

Promotor: S.M. Verduyn Lunel

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Political scientists Tom Louwerse, Simon Otjes & Cynthia van Vonno introduce the Dutch Parliamentary Behaviour Dataset, a record of parliamentary (voting) behaviour in the Dutch Tweede Kamer (Second Chamber, House of Representatives) since 1945.

Promotores: H.A. Udo De Haes, P.M. Brakefield

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

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This article explores how employees use leadership behaviours and how characteristics of the organizational context affect their engagement in leadership.

This study tests whether behavioural problems at a young age are related to early reading and mathematics development.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

Our mission: a positive impact. Our vision: community. By involving the world around us in our education and research we make a positive impact. We do this by applying Open Science.

Leiden University researchers and their collaborators report the development of new research frameworks that use day-to-day smartphone behavior gathered from a large sample of healthy people to help understand aging, and how aging alters with epilepsy and stroke. These reports occupy two back-to-back…

This edited volume draws from papers presented at the conference Closing the Gap | Responsibility in Cyberspace: Narratives and Practice, organized in June 2022 at the Egmont Palace in Brussels, Belgium, by Leiden University, as part of the EU Cyber Direct project.

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The Faculty of Social and Behavioural Sciences provides its ca. 5000 students with a thorough education in the social and behavioural sciences. The student population is very diverse and international in nature.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea