10,000 search results for “leiden” in the Public website
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Bacteria have the ability to alter their morphology in order to adapt to changing environments.
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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Media Technology MSc Program
Are you eager to bring your own questions and curiosity into scientific research? Do the creation of media and use of technology drive your research interests? Could you be a researcher who challenges scientific practice and pushes its boundaries?
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Prof.dr. J. Brouwer, Co-promotor: Dr. Remus Th. Dame
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Supporting medical teachers' learning: redesigning a program using characteristics of effective instructional development
In this research project characteristics of effective instructional development were identified that are appealing to medical teachers and relevant for medical education.
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Side@Ways: Mobile Margins and the Dynamics of Communication in Africa
This book is about the workings of networks of the mobile in Africa, a continent usually associated with the ‘global shadows’ of the world.
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Legitimiteit en rechtswaarborgen bij gesloten plaatsing van kinderen
On 7 March 2019, Maria de Jong-de Kruijf defended her thesis 'Legitimiteit en rechtswaarborgen bij gesloten plaatsing van kinderen'. The doctoral research was supervised by Prof. mr. M.R. Bruning en Prof. mr. T. Liefaard.
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Reviews
Several alumni, young alumni and students have been matched via the Leiden University Mentor Network.
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli
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DH Pilot Projects Symposium and Digital Skills Workshops – Winter Weeks
We hold the annual Digital Humanities Pilot Project Symposium and Digital Skills Winter Workshop Week in the last week of January. It is open to all LU staff and PhD/MA students.
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Clause linkage in Ket
This work provides a typologically oriented description of clause linkage strategies in Ket, a highly endangered language spoken in Central Siberia. It is now the only surviving member of the Yeniseian language family with the last remaining speakers residing in the north of Russia’s Krasnoyarsk pro…
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General Lab Facilities
Shared, general-purpose labs.
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Gibbs Processes and Applications
Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.
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On transport properties of Weyl semimetals
Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo
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Target Discovery
The goal of target discovery is to identify and validate proteins and biological pathways that are involved in the disease process. Modulating these target proteins and pathways with small molecules, therapeutic proteins or other biomolecules (e.g. mRNA) could deliver an effective and safe drug or v…
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Benchmarking Discrete Optimization Heuristics
This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Arithmetic of affine del Pezzo surfaces
In this thesis integral points on affine del Pezzo surfaces are studied.
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Research
Computers are becoming ever more powerful and are taking on more complex tasks. The Leiden Institute of Advanced Computer Science (LIACS) contributes to revolutionary scientific research and applies the latest inventions in the field, offering answers to today’s questions of society.
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Climate Call
In 2019, LUGO started a petition demanding an ambitious sustainability vision for 2030. This petition was formulated based on what LUGO deemed achievable rather than based on the restrictions of the present. We believe that sustainability should be one of the core values of the next central policy…
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Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
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Narrative reflective self-understanding: the corporeal
This PhD project analyses the politics and aesthetics of depictions of torture in American and European ‘war on terror’ films.
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L.A.D. F. Kaiser
The Leids Astronomisch Dispuut F. Kaiser is an association dedicated to the students who study astronomy in Leiden. In addition, they are also very involved in the public activities in the Old Observatory and help with the development and implementation of other projects in the building.
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Museums, collections and society, Yearbook 2021
Museums and collections are often frontpage news nowadays. The collections stored and curated in museums, universities and private institutions are no longer seen as 'neutral' entities to be enjoyed without political connotations.
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Effects of heavy fields on inflationary cosmology
Promotor: Prof.dr. A. Achucarro, Co-Promotor: J.W. van Holten
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Algorithm selection and configuration for Noisy Intermediate Scale Quantum methods for industrial applications
Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.
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Matchmaking for open innovation: perspectives on multi-sided markets
Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)
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ACTION
Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behaviour is seen. By combining interdisciplinary expertise the ACTION consortium…
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ArchaeoLandscapes International (ArcLand)
Archaeolandscapes International is an educational and scientific not-for-profit organisation with the objective to promote non-destructive prospecting methods for archaeological investigations.
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New handbook “EU State Aids”
The Europa Instituut is pleased to announce that on 21 November 2016 a new handbook “EU State Aids” (31 Chapters, 1500 pages) was published.
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Not so smooth after all: resolving dust and gas structures in protoplanetary disks
A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.
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The rebound effect through industrial ecology’s eyes : the case of transport eco-innovation
Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)
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Exploring charge transport properties and functionality of molecule-nanoparticle ensembles
Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken
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Teacher professional learning and collaboration in secondary schools
This dissertation focuses on teacher professional learning and collaboration in secondary schools.
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Towards Optical Detection of a Single Electron
Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.
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University Elections
This year, there are elections for the student and staff sections of the University Council and the student section of all faculty councils. You decide who represents you to university management. What topics and viewpoints are important to you? By voting, you ultimately have a say in university policy.…
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Sparsity-Based Algorithms for Inverse Problems
Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…
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Spin dynamics in general relativity
Promotor: J.W. van Holten
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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The Heirs Of Vijayanagara: Court Politics in Early Modern South India
This comparative study investigates court politics in four kingdoms that succeeded the south Indian Vijayanagara empire during the sixteenth to eighteenth centuries: Ikkeri, Tanjavur, Madurai, and Ramnad. Building on a unique combination of unexplored Indian texts and Dutch archival records, this research…
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Memory in Early Modern Europe 1500 - 1800
For early modern Europeans, the past was a measure of most things, good and bad. For that reason it was also hotly contested, manipulated, and far too important to be left to historians alone.
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Exploration on and of Networks
This dissertation consists of two parts, with the common theme
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Calculated Moves: Generating Air Combat Behaviour
By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.