Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

This dissertation focuses on the systematic vowel alternations displayed by the Proto-Germanic n-stems. The fact is, that many of these nouns now appear to have preserved the ablaut system of the Indo-European proto-language spoken some five millennia ago. In this respect, the n-stems are truly comparable…

On 25 January 2018 Yannick van den Brink defended his doctoral thesis titled ‘Voorlopige hechtenis in het Nederlands jeugdstrafrecht’ (‘Pre-trial detention in the Dutch juvenile justice system’). The doctoral research is supervised by Professor Ton Liefaard and Professor Mariëlle Bruning.

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Sarah Giest and Annemarie Samuels, both Assistant Professors at Leiden University, researched the quality and coverage of the data being collected for policiymakers to be used, specifically pertaining to minority groups.

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

This dissertation is concerned with the development of grammar. Starting from a usage-based perspective, which holds that children use domain-general learning mechanisms to acquire the grammatical patterns of their mother tongue, Beekhuizen shows how to operationalize various concepts from this tradition…

Open Science means not only sharing final research results but also the underlying data. A main way to do that is by making research data FAIR: Findable, Accessible, Interoperable and Reusable.

On 10 June 2021, Merinda Stewart defended her thesis 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon en Prof. J.J. Rijpma.

In ‘Dimensions of Free Speech’, Devrim Kabasakal Badamchi (Leiden University Institute of Political Science) offers a new theoretical framework for free speech by critically analysing the major justifications for free speech. Kabasakal Badamchi argues for a justification: namely the double-grounded…

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Selim Ahmetoğlu defended his thesis on 12 February 2019.

We consider the propagation of electrical signals through nerve fibres.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

This dissertation presents a grammar of Khwarshi, a Nakh-Daghestanian language.

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Sexual homicide is a rare phenomenon. Yet, sexual killing is widely reported on in the media. Even though academic research on sexual homicide is conducted abroad, in the Netherlands such research is virtually absent.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

Promotor: A.W. van der Vaart

Serhan Afacan defended his thesis on 23 June 2015

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Christopher Green defended his thesis on 26 February 2020

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

Eduard Fosch-Villaronga and Hadassah Drukarch from eLaw - Center for Law and Digital Technologies, recently published the book ‘AI for Healthcare Robotics’, published by CRC Press from Taylor and Francis Group in their AI for Everything Series.

Promotores: B.R. Katzy, J. de Vries, Co-Promotor: L.P. Groenewegen

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

Ruobin Han defended her thesis on 21 March 2017

Bioarchaeology covers the study of all biological remains from archaeological sites.

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Xinrong Ma defended her thesis on 13 February 2018

LENS is engaged in the drawing up a cartography of the mediascape, past and present, researching the dispositifs and ecologies of image production and presentation, which stretch across diverse geo-political areas as well as institutional, discursive and technological fields.

On 29 June May 2022 Yujing Tan successfully defended a doctoral thesis and graduated.

This thesis examines the impacts and challenges of water use of electric power system. This thesis found that there are large differences in water use of electricity technologies, with hydropower and thermal power being two large water users.

Beyond Empires explores the complexity of empire building from the point of view of self-organized networks, rather than from the point of view of the central state.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Promotor: Prof.dr. C.W.J. Beenakker

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

This dissertation assesses the influence of British Celtic on the phonological development of English during and shortly after the Anglo-Saxon settlement period, ca. AD 450-700.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

How do mycobacteria subvert the defenses of host immune cells?