Promotores: J.J.M.M. Rutten, F.S. de Boer, Co-promotor: M.M. Bonsangue

Quantum Delta NL, a research programme in which Leiden University participates, has been awarded 615 million euros from the National Growth Fund to help develop the Netherlands into a top player in quantum technology. This has been announced at the presentation of the honoured proposals in The Hague…

Lecture

Recently, Jaap van den Herik, professor emeritus Law and IT, was interviewed by the BNVKI (Benelux Association for Artificial Intelligence).

The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…

PhD defence

Leiden University Libraries invites you to the public lecture by Ted Underwood, Visiting Scaliger Professor. This lecture will be held on Thursday 21 November, from 16.00-17.00 in the Lipsius building, Room 0.19, Cleveringaplaats 1, Leiden. Afterwards, you can meet the new Visiting Scaliger Professor…

NWO is funding three partnership projects with the industry sector. The projects relate to speeding up the search for new medicines, studying the changes in proteins as medicine and developing analytical techniques for research on the building blocks of life.

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…

How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.

How do games help shape our perception of the past? Associate Professor Angus Mol receives a Vidi grant to answer this question.

A Rubicon Grant is awarded to dr Quentin Bourgeois for his reserach project

Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…

As of 1 March 2018, Elizabeth (Liesbeth) de Lange has been appointed as Professor of Predictive pharmacology at the Leiden Academic Centre for Drug Research (LACDR). She is head of the research group Predictive Pharmacology and mainly aims at developing mathematical models that can predict the effect…

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

A team of European astronomers under Leiden leadership has discovered that dust particles around a star already coagulate before the star is fully grown. These agglomerated dust particles are the first step in the formation of planets. The research publish their discovery in the journal of Nature As…

PhD candidates in medicine, Wouter Jan Geelhoed and Nan van Geloven, are the winners of the Leiden preliminary round of FameLab. They are through to the final on 22 April.

In health care, artificial intelligence is quite normal: it is used, for example, as an aid in making diagnoses. However, artificial intelligence is not yet used as much in drug development. A new prestigious partnership is therefore going to investigate how artificial intelligence can contribute to…

Lecture

Earlier this year, the public voted environmental scientist Paul Behrens Discoverer of the Year 2018. Behrens is an interdisciplinary scientist who wants to understand our impact on the planet. ‘Unfortunately, we are not doing enough. Huge changes are underway and we’re running out of time to avoid…

The Clinical Epidemiology department at the LUMC has set up a series of lectures for asylum seekers. The series has become a huge success.

Rong Yuang, PhD candidate from the Institute of Environmental Sciences investigated the impact of the renewable energy expansion on China’s carbon emission. On 17 May, she will defend her thesis. China is investing heavily in the development of low-carbon electricity sources, like nuclear, hydro-,…

Lecture, Film Screening + Q&A

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

Xander Tielens, Professor of Physics and Chemistry of the Interstellar Space, has been awarded an ERC Advanced Grant to study polycyclic aromatic hydrocarbons (PAHs) in space. The combination of astronomical observations, computer models and lab research makes the research highly interdisciplinary.

Which molecules go into forming planets? PhD candidate Christian Eistrup and his colleagues have created new models to research this question. Their findings could change our idea of which molecules were forming Jupiter or even Earth.

Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)

Former PhD student Cameron Mackie will been awarded not one, but two dissertation prizes for his thesis on the aromatic universe. His work could provide us with a virtual sniff of space. ‘These molecules in space likely smell like a big charcoal grill!’

Petr Steindl works on quantum dots in microcavities for his PhD research. He manipulates single-photons to create complex structures of light. Applications could include quantum communication and gates for quantum computers.

How is it that some covid-19 patients are affected much worse than others? Can we predict beforehand which of them will develop critical symptoms Professor Thomas Hankemeier, together with a diverse consortium of universities, academic hospitals and industrial partners, is looking for the answers to…

Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the

Nienke van der Marel has been awarded the New Horizons Prize in physics for her pioneering research on planet formation. This prize is given to young, promising researchers in physics or mathematics. The astronomer and her colleagues found the first observational evidence for 'dust traps' in disks around…

Comparison between babies and song-birds when they are learning a non-existent language—a study of this kind has never been tried before. But this is what Claartje Levelt, Carel ten Cate (Leiden University) and Jelle Zuidema (University of Amsterdam) are attempting.

Every week, Uwe Hensch walks past the Old Observatory in Leiden. In corona times, he decided to make a LEGO design of the historic building. His design is now finished and might go into production. You can help to make it happen.

What is Planet A? A new exhibition in the Old Observatory sheds light on how we all have different perceptions of earth. In five art installations, visitors are confronted with their own beliefs and how these differ from those of others.

Scientists remain puzzled by the sudden extinction of Neanderthals, some 40,000 years ago. New research by scientists from Eindhoven University of Technology, Leiden University and Wageningen University now suggests we might have been too quick in attributing the demise of Neanderthals to invasions…

How does a farmer decide if his cow is a prize winner? An anthropologist studying these farmers should not only look at the farmers themselves, but should in particular learn how they see the world. This is what Cristina Grasseni, the new Professor of Anthropology contends. Inaugural address on 30 O…

She left Leiden after her PhD and now, 14 years later, she returns as Professor of Extragalactic Astronomy. Mariska Kriek investigates how galaxies originate and evolve. And she is eagerly awaiting the launch for the new James Webb telescope: ‘The coolest things we are going to find are those we’re…

Elena Maria Rossi is fascinated by black holes. Her appointment as a professor was a long-held wish, partly because there are so few female professors in her field. ‘My appointment is also a milestone for the Leiden Observatory.’

Rodrigo Ochigame’s project explores how AI redefines scientific evidence, aiming to help scientists critically navigate these transformations with the Veni grant.

A team led by Erik Danen from the Leiden Academic Centre for Drug Research has received a 3 million euros NWO Science Groot grant to unravel the first steps of metastasis. Danen will work together with biologists and theoretical and experimental physicists from Dutch Universities. ‘Understanding these…

How does climate change affect the migration routes of birds? Mainly negatively, according to a new study from Yali Si from the CML. ‘It changes the timing of natural events differently in each region,’ she explains. ‘This can lead to a growing mismatch between the availability of food and the supposed…

According to a new study, for half of the world population the answer would be yes. For the other half: maybe? Leiden environmental researcher and head author Nicolas Navarre explains: ‘With improvements to crop yields, reductions in food waste, and changes in consumption patterns, 90% of people could…

Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…

From 14 to 29 PhD candidates, seven actively involved faculties and, above all, lots of innovative interdisciplinary research, all with data science as the common denominator. The university’s Data Science Research Programme (DSO) has proven so successful that after five years on a start-up grant it…

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Key publications of the Computational Drug Discovery group