This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

Promotor: M. Ubbink, Co-promotor: G. Siegal

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

The celebration of our up-and-coming science talent, that is the Psychology Science Day. Students stand proudly by their research posters and enrich the insights of fellow students, PhD candidates, postdocs and faculty with their explanations.

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Markus Davidsen defended his thesis on 16 October 2014

The Organ Art of the first female German concert organist and Bremen Cathedral organist and

Promotor: Prof.dr. G.P. van Wezel

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Create a world of opportunities with a master's degree from Leiden University.

Promotores: J. Kok, M. Chaudron (Chalmers University)

The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.

Promotor: Prof.dr. R.M.H. Merks

Promotor: Prof.dr. A.G.G.M. Tielens, Co-Promotor: J.B.R. Oonk

What makes a good historian? When historians raise this question, as they have done for centuries, they often do so to highlight that certain personal attitudes or dispositions are indispensable or studying the past. Yet their vieuws on what virtues, skills or competencies historians need most differ…

Promotor: Prof.dr. E.F. Smets

Can we predict fluctuations in suicidal ideation in a person’s daily life, from hour to hour?

The ARTIVES project studies imaginaries of diversity portrayed by artists in Lisbon and Rotterdam in their films, performances and (oral) literature with the aim to explore their transgressive potential of opening up possibilities of thinking differently about migration-related diversity. Their stories…

The project seeks to explore the interplay of valuation and inequalities in science, using the interdisciplinary and planet-critical field of forest research as empirical case. It examines which/whose knowledge is recognised on what grounds, and how social dimensions like gender and geographical location…

In this article, Lianne Visser contributed to the understanding of why collaborative governance is a challenging response to wicked problems.

In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…

This thesis describes a study from both a theoreticaL and an experimental point of view.

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

As part of Nexus 1492 Subproject 4: A Future for Diverse Caribbean Heritages, which seeks to shed light on how local communities interpret and engage with heritage in the present day, this doctoral study aims to gain insight into how indigenous heritage is represented in the school curriculum for social…

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

On 19 September 2019, Lynette Janssen defended her thesis 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. The doctoral research was supervised by Prof.mr. W.A.K. Rank and prof. M. Haentjens.

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

On Friday, November 22, students of the Archaeology Honours track participated in a poster presentation at the national archaeological congress 'De Reuvensdagen'. The posters were made as final assignment for the Honours Orientation Seminar, which is the introduction course for the Honours Track ‘Crossing…

On Friday 5 February 2021 the online conference of the Dutch Platform of Empirical Legal Studies (ELS) took place. This conference served as a platform to bring young, enthusiastic and driven ELS scholars together in a research community and enable them to learn more and discuss about empirical research…

Promotor: A. Kros

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Islam at 250: Studies in Memory of G.H.A. Juynboll is a collection of original articles on the state of Islamic sciences and Arabic culture in the early phases of their crystallization.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

On 10 June 2021, Merinda Stewart defended her thesis 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon en Prof. J.J. Rijpma.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

What is the role of emotion regulation in coping with interpersonal feedback?

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.