Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…

Promotor: B. van de Water

In this study, we evaluated the influence of supercritical carbon dioxide (scCO2) spray drying conditions, in the absence of organic solvent, on the ability to produce dry protein/trehalose formulations at 1:10 and 1:4 (w/w) ratios.

Biodiversity and trade: mitigating the impacts of non-food biomass global supply chains.

A full overview of THEOR PhD theses.

Through extensive archaeological and documentary research, this study aims to provide a detailed analysis of the maritime cultural landscape of St. Eustatius over the past four centuries. It focuses on bridging the gap between the marine and terrestrial worlds and demonstrates that in order to truly…

Pieter de la Court, Wassenaarseweg 52, 2333 AK, Leiden

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

The idea of global governance and trust in international institutions are apparently getting into deep water. But is there a legitimacy crisis? Not according to international élites, as Jan Aart Scholte (Leiden University), Soetkin Verhaegen (Maastricht University) and Jonas Tallberg (Stockholm University)…

Generations of Leiden students and academics have done archaeological research into the early medieval history of Oegstgeest. This makes this old settlement one of the best-documented sites from that era. In a new book, Leiden researchers take stock.

The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…

High resolution altitude data created by airborne LiDAR allow the investigation of large areas and often inaccessible tracts of land and has the potential to reveal undiscovered archaeological heritage.

How are the epidermal lipid pathways involved in health and disease.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

The authors in this volume explore how external innovations (products, technologies, services, institutions and processes) have been appropriated in African societies in order to be acceptable and relevant to local conditions, expectations and demands.

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Just as in phase 1, phase 2 of the Gorlaeus Building will focus on sustainable building.

Archaeological heritage management is concerned with the identification, protection, management and preservation of the material remains of human activity in the past (of whatever period and in whichever region of the world) and with the interaction that this involves with all kinds of stakeholders.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

The Near East, situated at the nexus of Europe, Africa, and Asia, was central to the development of ancient societies in all three continents.

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).

Promotor: Prof.dr. H.L.V. Linnartz

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

This week 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' by Peter Verstraten was published by Amsterdam University Press, the sequel to Humor and Irony in Dutch Post-war Fiction Film from 2016. Each chapter in his 482-page new study begins with a title of Fons Rademakers who made films…

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Promotor: J. A. Bouwstra

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, Dr. B.W. Hoeksema

Room 4.28 in the LMUY Building is a dedicated lecture room for the Media Technology MSc program. Finding it for the first time may be challenging. Below is a description of how to find it.

Sustainable energy from wind and solar is most readily available near the sea.

The Institute of Public Law comprises all areas of public law, with the exception of criminal law, and including labour law.

Since 2006, HJD has made an important contribution to shaping diplomatic studies as an international academic field. Our new HJD Diplomacy Reading List presents a diverse collection of analyses categorized into forty-five topics published in HJD over the years. We hope these lists prove a valuable resource…

Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan

Below you will find an overview of all PRE-Classes provided by the various programmes of Leiden University. For each section, you can find a description of the content and more specific information about the requirements for participation in the Class.

The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…

PhD defence

The fact that a significant number of seats in the Dutch provincial councils are now occupied by members of the Dutch Farmer-Citizen Movement (BoerBurgerBeweging, BBB) who have an agricultural background need not lead to conflicts of interest when voting on, for example, nitrogen emissions. This is…

In 2014 Hans-Martien ten Napel received a Research Fellowship in Legal Studies at the Center of Theological Inquiry in Princeton, NJ. The book he wrote as a result of this fellowship was published last week by Routledge Law.

From 26 August until 5 September 2019, a group of 20 Chinese government officials, industry representatives and academics attended an intensive course on space law and policy at the International Institute of Air and Space Law, organized in cooperation with Avans+ in Breda.

In 2021, the National Cyber Security Centre (NCSC) asked Leiden University to conduct a rapid review of best practices and possibilities for follow-up research on the integration of behavioral sciences in security by design methodologies and projects. This academic field is called security by behavioral…

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

An investigation into how racial stereotypes were created and used in the European Middle Ages.