Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

Can we build a biosensor to detect neuroblastoma markers in urine using the chemotaxis system in E. coli?

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Do you still use the uMail address from your alumnus account? Then it is important to know that this mailbox will be discontinued. This is because just a handful of alumni use the uMail addresses and associated mailboxes that we currently maintain for thousands of alumni.

A consortium of knowledge institutes, led by Leiden University launched an online platform for analysis and research of sports and movement data on 7 September: Sport Data Valley. The platform offers coaches and athletes insight into their data and makes research on sports and exercise more efficient,…

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Research from the Living Lab is important for society. For example, scientists from the Living Lab discovered that the pesticide thiacloprid is up to 2,500 times more harmful to insects than was thought on the basis of regular lab research. Partly because of this discovery, the European Commission decided…

The Saalian archaeological record at Maastricht-Belvédère (the Netherlands).

Since June this year, the ACPA PhD-council has been organising a monthly forum for doctoral students across ACPA's PhD-programmes.

How can ‘Big Data’ be used in development and humanitarian aid, and what are the risks? Leiden University and the United Nation’s Global Pulse are organising an international expert meeting in The Hague on 23 October.

Mediterranean archaeologist Dr Anita Casarotto has been awarded a grant of € 5,800 from the Byvanck Fonds for her research on unlocking important data for regional archaeological investigations in the Mediterranean. In collaboration with Leiden University and the KNIR (Royal Netherlands Institute in…

PhD defence

PhD defence

PhD defence

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…

Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…

The Drug Discovery and Safety specialisation consists of compulsory and optional components.

How do we deal with large sources of greenhouse gases? Do schools provide a socially-inclusive environment for all children? And how can we protect Earth’s nature? These questions have two things in common: they are complex global challenges, and data can help answer them. Mitra Baratchi is computer…

As of 1 July 2019, Bart Custers is appointed as Professor of Law and Data Science at Leiden University. The chair is established at eLaw, the center for Law and Digital Technologies at the Faculty of Law. Bart Custers will focus on the intersection of law and digital technologies, on the one hand on…

The new inter-university centre set up by Leiden University, Delft University of Technology and Erasmus University Rotterdam is to apply ‘big data’ research for urban issues.

Data about COVID-19 were everywhere during the pandemic, but how will all this data continue to be managed and kept open so that it is usable in the future? We spoke with Kathleen Gregory, researcher at the Centre for Science and Technology Studies (CWTS), who will study this question in a new project…

Professor Anne Meuwese is calling on governments to show more vulnerability when it comes to providing information about how they function.

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

PhD defence

A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a…

Prof. Zangenberg came to Leiden in 2006 as Professor for New Testament and Early Christian Literature and is now Chair for the History and Culture of Ancient Judaism and Early Christianity.

Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

Taner Kuru, an eLaw alumnus, was awarded the prestigious European Data Protection Law Review ‘Young Scholar Award’ for his paper on the shortcomings in the GDPR for the regulation of genetic testing at the prestigious Computers, Privacy and Data Protection Conference (CPDP).

The European Space Agency (ESA) has published an interim data release from Gaia, the space telescope mapping out the Milky Way in 3D. The first scientific papers published today reveal half a million stars in the Omega Centauri globular cluster, nearly 400 candidate gravitational lensers and the positions…

In this thesis,

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

In the spring of 2024 the Faculty of Archaeology welcomed a new postdoc. Dr Adam Benfer, originally from the United States, occupies a double position as a researcher in the project of Alex Geurds and as the Faculty’s Data Steward. ‘It is pretty much what the title says: I steward data. Essentially,…

Indira Nederpelt was elected as the winner of the Young Investigator Award for best oral presentation titled ‘’Kinetic characterization of clinically used GnRH peptide agonists’’.

PhD defence

Some children start life with a disadvantage. Sometimes even before they are born. A new research project involving Professor Wessel Kraaij of Leiden University investigates how data science can help give these children a good start in life.

The Dutch police force has been deliberately storing personal data relating to millions of Dutch people for many years now. In doing so, the institution has been knowingly breaking the law. Bart Schermer, Professor of Law and Digital Technology expressed his concerns on Follow the Money – a platform…

On 15 November Joost Visser started as Professor of Large Scale Software and Data Science at the Leiden Institute of Advanced Computer Science (LIACS). He will head the software engineering research at LIACS and becomes head of the ICT in Business and the Public Sector master's program.

PhD defence

Festival

On November 30th Joost Grootens gave a lecture at the workshop ‘Data on Display: Visualisation as a form of argumentation in exhibitions’ organised by the Museumsakademie Joanneum, Graz (Austria)