1,427 search results for “care development” in the Public website
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High-throughput screening for developmental and reproductive toxicity
Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?
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Meuwese on new developments in Dutch cabinet’s response to child benefits scandal
In recent days and weeks, experts have been falling over themselves to point the finger at the main culprit in the Dutch child benefits scandal. Although this debate is fascinating, equally important are the broader lessons to be drawn from the scandal in relation to constitutional and administrative…
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Information in the Humanitarian Domain: Legal and Space-Related Developments
In February 2023, the International Institute of Air and Space Law and the Kalshoven-Gieskes Forum for International Humanitarian Law organised a seminar on the topic of 'The optimisation of the use of satellite information in the humanitarian domain – Legal and space-related developments' at Leiden…
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Access to Justice in Indonesia
How do poor and disadvantaged Indonesians address the injustices they face in daily life and how can their situation be improved?
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Eyetracking and psychophysiology indicators of social cognition and emotion in adults with Klinefelter syndrome
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Tom Kouwenhoven wants to develop a bridge between AI and humans
It is a familiar phenomenon: you ask the assistant on your phone to call your mother, but it calls a friend instead. Tom Kouwenhoven, PhD student in the SAILS programme, investigates how humans and Artificial Intelligence (AI) can better communicate with each other, so that these kinds of situations…
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Tom Kouwenhoven wants to develop a bridge between AI and humans
It is a familiar phenomenon: you ask the assistant on your phone to call your mother, but it calls a friend instead. Tom Kouwenhoven, PhD student in the SAILS programme, investigates how humans and Artificial Intelligence (AI) can better communicate with each other, so that these kinds of situations…
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Master’s students create Graduate Journal: ‘It represents the development we’ve achieved’
A celebration was held in the Tabú restaurant: Mark Rutgers, Dean of the Faculty of Humanities, was presented with the first copy of LEAP, a journal where Humanities master’s students can prepare for an academic career by publishing articles themselves.
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‘Think what you want to do about international students before developing your housing policy’
Students used to live with a landlady or even with the professor whose course they were taking. Student accommodation has since become more professional, making it something the new government will have to tackle. What should the new government do?
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Eduard Fosch-Villaronga & Louk van Doorn win the DT4REGIONS Ideathon on AI Potential for Preventive Healthcare
eLaw - Center of Law and Digital technologies from Leiden Law School, and the Vascular Surgery Department at Leiden University Medical Centre in the Netherlands, join forces to explore the use of AI for diabetes and secondary prevention of diabetic foot problems and won a prize for it.
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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PhD Thesis: Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Recently, the PhD thesis of Lolu Danso Eweje appeared entitled ’Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin’.
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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PROPER: ‘Near-patient’ prostate cancer models for the assessment of disease prognosis and therapy
How to identify patients at risk of developing devastating, metastatic disease and facilitate the development of personalised treatment for prostate cancer patients?
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FishForPharma: Training network on zebrafish infection models for pharmaceutical screens
How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?
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''Portal to Care: General practitioners’ decision-making on child and youth mental health problems and the influence of their (lived) experience''
PhD defence
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TARGETBIO: Transmission of Antimicrobial Resistance Genes and Engineered DNA from Transgenic Biosystems in Nature
This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.
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Nitric oxide in defence against mycobacterial infection
Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Special education and autism
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Inhibition of MicroRNA-494 reduces carotid artery atherosclerotic lesion development and increases plaque stability
Publication by: Anouk Wezel, Sabine Welten, Wida Razawy, Max Lagraauw, Margreet de Vries, Eveline Goossens, Martin Boonstra, Jaap Hamming, Ekambar Kandimalla, Johan Kuiper, Paul Quax, Yaël Nossent and Ilze Bot. Annals of Surgery. 2015;262:841-848.
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Twentieth anniversary of the Lorentz Center: developing ideas in a scientific bubble
The 20th anniversary of the Lorentz Center will be celebrated on 28 June 2017 with the opening of an exhibition in the Oude UB. For two decades already, the Center has been a place of retreat for groups of international academics who want to explore a single issue.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Organisation
The Institute of Education and Child Studies is part of the Faculty of Social and Behavioural Sciences at Leiden University. The institute is governed by an Institute Board under the direction of a rotating chairman, i.e. the Scientific Director and an Director of Studies. The Institute Board is…
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The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
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The added value of multimedia to repeated story book reading in preschool age
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MeRGeR: Physiological significance of the glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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Agrobacterium-mediated protein therapy for genome editing
Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?
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The role of 14-3-3 proteins in ion homeostasis in the yeast Saccharomyces cerevisiae
We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.
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Leiden PhD team in finals international pharmacological competition
A team of five PhD students from Leiden University is in the running for first prize in the Pharmacometrics Skills Competition. In a drug development simulation, they apply their mathematical pharmacological skills to solve clinical problems. On 24 March they will compete in the finals in Orlando, F…
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Development matters - Longitudinal pathways in brain and behavior
Conference
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Mathematical model helps to explain the formation of spine and ribs
Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.
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Working paper: 'Export restrictions and policy space for sustainable development: Lessons from trends in the regulation of export restrictions (2012-2016)'
On 16 January 2018, the Asia-Pacific Research and Training Network on Trade (ARTNeT) published Fengan Jiang's (Richard) working paper entitled 'Export restrictions and policy space for sustainable development: Lessons from trends in the regulation of export restrictions (2012-2016)''.
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‘Data science has crept into the faculties’ DNA’
From 14 to 29 PhD candidates, seven actively involved faculties and, above all, lots of innovative interdisciplinary research, all with data science as the common denominator. The university’s Data Science Research Programme (DSO) has proven so successful that after five years on a start-up grant it…
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Environmental Biology
This research programme aims to increase the scientific understanding of how current and emerging anthropogenic threats affect biodiversity and ecosystem services to facilitate strategic management of natural resources. To this end, we address urgent challenges in relation to the mechanisms involved…
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Innovative Leiden research receives NWO grant
On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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We all BENEFIT: The Ecosystem for Healthy Living
The modification of risk factors and related health behaviors lies at the very core of adequate cardiovascular risk management, yet evidence shows that the majority of people with cardiovascular disease (CVD) fail to achieve a healthy lifestyle in the long term. The main objective of this project is…
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TRANSAUTOPHAGY: European network for multidisciplinary research and translation of autophagy knowledge
TRANSAUTOPHAGY is a European COST action to promote multidisciplinary research on autophagy and translation of knowledge to applications.
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A few remarks on the latest developments at NVIC from director Dr Rudolf de Jong
Dear friends of the NVIC,
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From stress to success: how actinobacteria exploit life without a cell wall
The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.
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Making Environmental Regulation Work for the People
The project’s overall goal is to improve Indonesia’s environmental legal framework and its implementation by strengthening the regulatory capacity of the government, and by enhancing the capacity of CSOs and scholars to hold the government accountable for its regulatory performance.
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Promoting Legal Certainty and Increasing Judicial Skills in Selected Areas
How can the legal and socio-legal research skills of Indonesian jurists be increased in order to promote legal certainty and to strengthen the capacity of the judicial training in the country?