This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes

Promotores: Prof.dr. M. Franx & Prof.dr. P.G. van Dokkum (Yale University)

Political scientist Luzia Helfer (Leiden University) empirically tested claims about media-politics relatiopns using unique data from experimental studies with elected politicians and political journalists in Switzerland and the Netherlands.

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

An experimental and microwear approach to Early Iron Age vessel biographies

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

The Brain and Education lab is a research group in the Institute of Education and Child Studies at Leiden University in the Netherlands. We use a Developmental Cognitive Neuroscience approach to study the development of complex cognitive processes involved in learning and academic skills such as reading…

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

D.P. Kok defended his thesis on 10 October 2017

Considering the fact that for a long time women were not allowed to participate either in university life nor in academia, women found different ways they could be included.

Chapter 1,contains the numerical verification of the Birch and Swinnerton-Dyer conjecture for hundreds of Jacobians of hyperelliptic curves of genus 2, 3, 4 and 5.

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

Biodiversity enables ecosystems to thrive through the synergy of functional differences among organisms. While human well-being strongly depends on biodiversity-driven ecosystem services, human actions are also at the root of current unprecedented biodiversity declines.

It is difficult to hold international organisations (IOs) accountable for human rights violations. Gisela Hirschmann (Institute of Political Science, Leiden University) introduces the concept of pluralist accountability, whereby third parties set the standards for IOs’ actions in relation to human rights,…

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Introducing five papers about of the impact of crises on the governance, decision-making, and institutional design of the Euro Area, political scientists Valerie D'Erman (University of Victoria, Canada), Paul Schure (University of Victoria, Canada) and Amy Verdun (Leiden University) summarise the 'lessons…

The central question in this book is whether there is a human right to family unification.

Cynthia van Vonno, political scientist at Leiden University, explains why individual MPs vote according to the party group line.

In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…

What drives the restrictiveness of immigration reforms? Political scientists Katharina Natter (Leiden University), Mathias Czaika (Danube University Krems) and Hein de Haas (University of Amsterdam) analysed immigration reforms in 21 Western immigration countries between 1970 and 2012. They found that…

This thesis is a sample-based typological study of formal and semantic patterns in terms for a selection of referring (

On 26 juni 2018, Claire Achmad defended her doctoral thesis 'Children’s Rights in International Commercial Surrogacy: Exploring the Challenges from a Child Rights, Public International Law Perspective'. The doctoral research was supervised by Prof. Dr. Mariëlle Bruning.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

The Leiden University doctoral / PhD programme takes around four years of study and consists of independent and original research under the supervision of a professor.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Promotor: Prof.dr. E. R. Eliel, Co-Promotor: M.J.A. de Dood

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

The Sport Data Center (SDC) consists of the data science disciplines of Leiden University and Technical University Delft, combined with the sport science branches of the Amsterdam Institute for Sport Science and the Sport Engineering Institute of the Technical University of Delft.

LIAS aims to advance the globally conscious vision of area studies, both within and outside the academic community. Focusing on Asia and the Middle East, the institute is a meeting place of multiple fields of inquiry, theories and methods, historical periods, and areas.

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

Today, knowledge is the most crucial element to stimulate organizational competitiveness and economic development.

Political scientist Wouter Veenendaal (Leiden University) provides an in-depth case study of clientelism in Malta, the smallest member state of the European Union. He reveals that not only that patron–client linkages are a ubiquitous feature of political life in Malta, but also that the smallness of…

In this thesis we study products of linear error correcting codes.

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

In our research protein translocation from Agrobacterium into yeast and plant cells is studied to obtain fundamental insights in the translocation process

On 15 February 2023 Uzume Wijnsma successfully defended a doctoral thesis and graduated.