941 search results for “protein” in the Public website
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Steering the immune system with liposomes
Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…
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Eight researchers to travel abroad on Rubicon grant
Eight young researchers from Leiden University have received a Rubicon grant from the Dutch Research Council (NWO). This will allow them to conduct research at a top institute or university abroad.
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Gerard van Westen appointed as full Professor of Artificial Intelligence and Medicinal Chemistry
Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…
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New management structure for nanoscopy centre NeCEN
A new executive board has been installed at NeCEN, a state-of-the art facility that offers the most advanced cryo-electron microscopes worldwide. The new board members are full of excitement: what are their ideas for the future of the facility?
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Our Talents and Discoveries 2016
Christmas is coming, which means that 'Our Talents and Discoveries 2016' has been distributed. This also means that it is time to vote for the 'Discoverer of the year 2016'. Each of the eight institutes nominated one researcher that excelled in the past year. Who is your favourite?
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NWO Vidi grant for 11 Leiden researchers
Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.
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A synthetic vaccine against meningococcus
Leiden chemists recreated the bacterial capsule of meningococcus in the lab. With a few modifications, these capsules can serve as an extra safe and effective vaccine against these notorious bacteria, which can cause, for example, meningitis. PhD candidate Jacopo Enotarpi and his team published the…
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Vici grants for seven researchers from Leiden University
From research on stellar winds to sign language: an impressive seven researchers from Leiden University will receive a prestigious Vici grant from the Dutch Research Council (NWO).
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Changing enzymes for clean energy and disease prevention
They can play a role in metabolic disorders and can break down tough plant fibers: β-glycosidases are enzymes that play many roles in nature. Fredj Ben Bdira changed these enzymes in order to enhance the production of clean energy and to improve the treatment of patients with metabolic diseases.
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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2.8 million euros for photosynthesis research
In the programme NWO Open Competition Domain Science - GROOT, twenty new consortia will start a large research project. This boost of more than 47 million euros will make new research possible in the science domain. Among the winners is the Nanoscale Regulators of Photosynthesis consortium in which…
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Break-through in the genetic modification of plants
A collaboration between the IBL and LUMC has resulted in the discovery that the polymerase theta enzyme is essential for the integration of Agrobacterium T-DNA into the genome of plants. The finding means a break-through for the development of more efficient systems for targeted genome modification…
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IBL symposium “Integrative Biology towards Healthy Communities”
On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.
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IBL-research interview: Daniel Rozen
Daniel Rozen (45), at the IBL since September 2012, uses bacteria in laboratory tests on experimental evolution to study the ecology and genetics of adaptation. His research has applied importance, as it reveals how bacteria may be induced to produce new antibiotics. Last January, Rozen received the…
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How Europe will be better prepared for the next pandemic
The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…
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Movements of steroid receptors inside the cell nucleus unraveled
Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.
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Tumours can use ‘remote control’ to attract blood vessels
Researchers at Leiden University have demonstrated that tumours can apply mechanical means to attract the blood vessels they need to be able to grow. The team published this discovery on 2 March in Nature Scientific Reports.
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In Ovo raises 34 million to stop the killing of day-old male chicks
Dutch scale-up In Ovo, a spin-off of Leiden University, has raised 34 million euros to accelerate its international growth and scale-up plans. The new funding is supported by Leiden University’s Libertatis Ergo Holding. The funding has also been provided by, among others, impact investors ECBF and ABN…
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Mario van der Stelt and Laura Heitman have been awarded an NWO ECHO-STIP grant
On Friday May 3rd 2013 NWO has announced that Dr. Mario van der Stelt, Division of Bio-Organic Synthesis (LIC) and Dr. Laura Heitman, Division of Medicinal Chemistry (LACDR), have been awarded with an ECHO-STIP grant for their project, entitled: “Novel target engagement biomarkers for better drug ca…
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‘Building blocks for life' may originate in space
Amino acids are the building blocks for life on earth. They may originate in space and reach the Earth via comets and meteorites. Daniël Paardekooper examined part of this hypothesis. PhD defence on 5 July.
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How a nationally recommended diet can improve the environment
Changing your diet can improve both your health and the environment. A new study shows that the national dietary recommendations on reducing animal products can reduce environmental impacts in most high-income nations. Publication in PNAS journal.
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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Preventing or curing diseases with X-omics
In April, the X-omics initiative was granted 17 million euros from the Dutch Organization for Scientific Research. The subsidy is part of the National Roadmap for large-scale scientific infrastructure, intended to build or renew large-scale research facilities. What new insights will this investment…
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Controlling active matter with curvature
Nematic liquid crystals form the key ingredients of most tv screens. The active version of these complex fluids forms a useful model for physicists to research the responses of active matter—like bacteria or traffic flows—to mechanical and geometrical cues. An international research team publishes their…
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New Directors of Education IBL
Remko Offringa, Associate Professor in Plant Developmental Genetics, and Associate Professor in Molecular Microbiology Arthur Ram both have been appointed as the new Directors of Education at the IBL. Offringa in the role as Director of Education for the Master program and Ram as Director for the Bachelor…
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17.9 million euro for national NMR Roadmap consortium
The National Roadmap for Large-Scale Research Facilities programme of NWO enables the building or renovation of research facilities with international allure. Leiden NMR groups take part in the uNMR-NL consortium coordinated by Marc Baldus (Utrecht University) that has been awarded almost 18 million…
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New project funded to study Alzheimer's disease
Researchers from Leiden University will develop a new approach to study the biomarkers of Alzeimer’s disease. This approach focusses on the molecular messengers of the cells. The project, led by Thomas Hankemeier and coordinated by Yuliya Shakalisava (Leiden Academic Centre for Drug Research, LACDR),…
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Four Leiden researchers awarded Rubicon grants
Four promising young researchers will be able to conduct two years of research at a university abroad thanks to a Rubicon grant from the Dutch Research Council (NWO). The Leiden laureates are Renske Janssen, Girija Josh, Anne van der Meij and Yana van der Weegen.
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Physicists link specific iron forms to Alzheimer’s
There have been indications for decades that there is a link between increased iron levels in the brain and Alzheimer’s disease. Leiden physicists find this connection as well, thereby now making a distinction between different forms of iron. They identify specific iron forms that increase in Alzheimer’s…
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Iprotics Wins the Venture Challenge Spring 2022
The winner of the 2022 Spring edition of the NWO Venture Challenge was announced during the Dutch Biotech Event. The innovative startup Iprotics has developed specific proteasome inhibitors that potentially treat multiple myeloma (MM) without the side-effects known from traditional proteasome inhibi…
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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Human DNA softer than DNA single-celled life
Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.
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Veni grants for 19 young Leiden researchers
Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.
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Healthcare and population health: AI research in Leiden, Delft and Rotterdam
‘Our health is the area that stands to gain most from artificial intelligence.’ The three universities in Zuid-Holland are helping make these gains. Three researchers talk about their collaborative research into AI for health, drug discovery and healthcare in the AI knowledge cluster in Zuid-Holland.…
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Veni grants for 25 Leiden researchers
From molecular ping-pong to cassava in the Amazon, and from extraterrestrial life to special antibodies. Twenty-five researchers from Leiden University have been awarded a Veni grant from the NWO. A grant of up to 250,000 euros will give them the opportunity to further elaborate their own ideas over…
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LED3 Lecture: Expanding the Genetic Code – Novel Chemistries for Biology
Lecture
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LED3 Lecture - Elucidating inositol pyrophosphate signaling with chemical tools
Lecture
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Awards and Grants 2023
On this page you will find an overview of awards and prizes granted to our staff and students in 2023, as well as special appointments at Leiden University and other institutions.
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Proteomics and functional investigation of SUMO and ubiquitin E3 ligases
PhD defence
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18 Veni subsidies for Leiden, 8 for our faculty!
This year, NWO has awarded a Veni subsidy to 143 young researchers who have recently obtained their PhD. 17 of these researchers are at Leiden University and one works at the LUMC. The successful applicants will each receive 250,000 euro to develop their ideas and carry out research over a period of…
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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Virologist Eric Snijder: ‘Vaccination will be going well in 2021’
The research group of Eric Snijder, Professor of Molecular Virology (LUMC), has been conducting research on coronaviruses for decades. Then in March this year their work accelerated at an unprecedented rate. The first new results are now available: insight into how the virus replicates.
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Bitter Sweet Symphony
PhD defence
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LIC Guest Lecture: Controlling biological systems: From nanopore-forming toxins to a chemical-genetic system to map ZDHHC-specific S-acylation
Lecture
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LED3 Lecture: Molecular glues in drug discovery
Lecture
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Briegel winner in global competition by the Moore Foundation
Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.
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‘How can we translate the language of cells into cancer therapies?’
On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…