2,018 search results for “cancer drie discovery initiatief” in the Public website
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Awards and Grants 2023
On this page you will find an overview of awards and prizes granted to our staff and students in 2023, as well as special appointments at Leiden University and other institutions.
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Life Science & Technology (MSc)
Increased molecular knowledge of the mechanisms of processes in the cell can lead to better medicines or new methods for combating diseases. Our MSc students in Life Science and Technology (LST) specifically learn to understand the molecular and structural chemical and biological aspects of disease-related…
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University couple marries ‘in front of all of Leiden’ on 3 October
They have known each other since they were small but Rianne and Tom first fell in love when working together at the university. That love culminated in a fairytale wedding amid all the revelry last 3 October.
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Gert Jan Geertjes defends preliminary advice Nederlandse Vereniging voor Wetgeving
At the annual conference of the Nederlandse Vereniging voor Wetgeving (the Dutch association for legislation) that was held in the Auditorium of the Ministries of Internal Affairs and Kingdom Relations and Justice and Security in The Hague on Thursday 6 October, Gert Jan Geertjens defended the draft…
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Hydrodynamics and the quantum butterfly effect in Black Holes and large N quantum field theories
Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?
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Aging and Immunity
The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.
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Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
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A much-needed new class of antibiotics
Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…
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Adding fuel to the conflict : how gas reserves complicate the Cyprus question
In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.
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Journal of Quaternary Science
Scientists, including our faculty colleague Dr. Mike Field, studying an exceptionally well-preserved woolly rhinoceros have revealed details of what Britain's environment was like 42,000 years ago. The beast's remains were discovered in Staffordshire in 2002, buried alongside other preserved organisms…
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Microscale Analytical Tools
Enabling volume-restricted metabolomics using next-generation microscale analytical tools.
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SCALES project
How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Landscapes of Survival
The Archaeology and Epigraphy of Jordan’s North-Eastern Desert and Beyond
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Search for mechanisms to control massless electrons in graphene
Beenakker
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Books and films
Leiden University has made history with its many scientific discoveries; a history that is also illustrated in a variety of books and films.
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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation
Source: PLoS ONE, Volume 10, Issue 3 (2015)
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The Encyclopedia of Global Human Migration
The Encyclopedia of Global Human Migration provides a complete exploration of the prominent themes, events, and theoretical underpinnings of the movements of human populations from prehistory to the present day.
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Initiatives
LUCITH runs a number of initiatives and programmes. Below you will find a list of initiatives and activities by the Centre for Islamic Thought and History.
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Research
Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.
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Lava worlds: characterising atmospheres of impossible nature
Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune.
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Discover More HyperVelocity Stars to shed light on the Galaxy
Rossi
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Early death of massive galaxies in the distant universe
Promotor: M. Franx, Co-Promotor: I.F. Labbé
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Revealing the nature of new low-frequency radio source populations
It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.
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European Prehistory
Our research deals with the deep history of Europe and Eurasia, from the inception of farming up until the beginning of the Roman Period. This was a period in which key developments took place that had a profound impact on European landscapes and society until the present day. Our research and teaching…
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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A document classifier for medicinal chemistry publications trained on the ChEMBL corpus
Source: J Cheminform, Volume 6, Issue 1 (2014)
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Operators in the lexicon. On the negative logic of natural language
Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?
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Young suns and infant planets: Probing the origins of solar systems
Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).
- Leiden Observatory
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The Paippalādasaṃhitā of the Atharvaveda: A new critical edition of the three 'new' Anuvākas of Kāṇḍa 17 with English translation and commentary
On the 11th of June, Umberto Selva successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Umberto on this great result.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Imagined Voices- A Poetics of Music-Text-Film
Imagined Voices deals with a form of composition, music with on-screen text, in which the dynamic between sound, words and visuals is explored.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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Biomedical Metabolomics Facility Leiden
The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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Jebel Aruda: An Uruk period temple and settlement in Syria (Volume I)
Volume I: Excavation and Material Culture
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Jebel Aruda: An Uruk period temple and settlement in Syria (Volume II)
Volume II: Plates of Room Contents
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Lightning Pose: improved animal pose estimation
Science begets technology but technology also begets science. Anne Urai from the Leiden Institute of Psychology is part of an international team team that rolls out a new, user-friendly, plug-and-play AI tool they hope will become an engine of discovery by quantifying the growing volume of recorded…
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Programme
On this page the programme and sessions can be found. Keynote speakers will be announced soon.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Prepare for your studies
You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.