This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

The Netherlands has also announced special measures to fight SARS-CoV-2 coronavirus. These measures have at times caused questionable behaviour, such as stockpiling or charging exorbitant sums for masks. But the intentions behind this seemingly antisocial behaviour are not necessarily bad, says Professor…

Following the New Year's speech of Dean Hanna Swaab a total of 4 prize winners were showered with praise and flowers during the new year's reception 10 January, 2017. Anthropologist Igor Boog won the Casimir Prize for best lecturer, pedagogue Ilona Schoep the Master Thesis Prize, political scientist…

Could policies aimed at preventing radicalisation undermine the very trust and social cohesion they aim to strengthen?

CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

PhD defence

PhD defence

PhD defence

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Using brain imaging to discover the area in the brain that recognizes emotion.

The Social Resilience & Security interdisciplinary programme broadens its scope by embedding two research projects lead by Dr. Joanne Mouthaan. The projects adress suicide prevention skills and mental health of Ukraine refugees. Both projects will be integrated in the programme with the aim to improve…

Vietnam’s record of expanding access to education, and especially its performance on international assessments such as PISA, has raised questions about what Vietnam got right, how, and why and what insights Vietnam’s experiences might offer for efforts at improving the performance of education systems…

Chemist Liubov Belyaeva, psychologist Janna Marie Bas-Hoogendam and LUMC researcher Elisa Giacomelli have received a Rubicon Grand and will therefore be able to conduct research at a top institution abroad.

Nature, nurture and neural mechanisms of social emotion regulation in childhood

There's a myth that people with autism avoid eye contact in conversations. This can come across as indifferent. Unjustified, stresses Jiayin Zhao, who is doing her PhD research on the socio-emotional development of children with autism. 'That people with autism don't care is anything but true.'

What are the functions of the endocannabinoid system?

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

This thesis describes a study from both a theoreticaL and an experimental point of view.

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Dr. Pauline Aarten tries to find answers of the impact a road traffic accident has on the victims and surviving relatives and how we can improve their position.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

Legitimacy is generally a term that is associated with the state. The term surfaces when there are problems with state legitimacy—when it is lacking or absent. This present volume attempts to think through the relevance of the concept of legitimacy for other political actors than the state.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

We investigate emergent structures and dynamics of soft materials self-assembled from microscopic constituents.

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Cognitive psychology is the study of cognitive functions such as attention, memory, consciousness, emotion, language and action control. The goal is to understand the complex relationships between brain, mind and behavior.

Develop EPR instrumentation and methodology to investigate intrinsically disordered proteins (IDPs).

How do genetic and environmental factors make us vulnerable to depression?

Consensus and harmony or balance and reciprocity?

The research connected to this topic is related to E-health.