Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.

Researchers led by Professor of Chemistry Marcellus Ubbink have recently published a study in Proceedings of the National Academy of Sciences (PNAS) about the dynamics of an important redox enzyme. This work was accomplished thanks to an NWO VICI subsidy granted to Professor Ubbink.

PhD candidate Marc Baggelaar of the Leiden Institute of Chemistry (LIC) graduated cum laude on Thursday 6 April. His thesis on the endocannabinoid system in the brain is very comprehensive and of high quality, according to the jury. ‘A very talented young scientist, that definitely belongs to the top…

Three Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Scientific Research (NWO). They each receive 1.5 million Euro to develop their own research project in the coming 5 years.

During orange juice production only around a half of every orange is turned into juice. Lizah van der Aart and Blair Berger, both MSc-students at the IBL, and Ryan Bogaars from Delft University, received an NWO-scholarship to develop a novel method to extract natural products from orange residue.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

Prof. dr. Arnold Tukker will be appointed on 1 October 2013 as Chair of Industrial Ecology at the Faculty of Science of Leiden University. He will work at the Institute of Environmental Sciences (CML), and also become the new director of this institute.

What do a novel anti-ageing ingredient for cosmetics and a new type of chicken feed have in common? They were both produced using a new solvent developed by Leiden biologists in 2011. The medium is neither solid nor liquid, and the industry is now starting to see it’s many possibilities.

We do it every day but barely give it a thought: chewing our food. But the ‘simple’ process of masticating food may have played a crucial role in the evolution of our jaws, facial muscles and teeth.

Lecture

Lecture

Overview of the publications of the department of Environmental Biology (1972-2015)

Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.

Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…

Playing with tiny building blocks might sound like child’s play, but Vera Meester knows better. On June 7 she will defend her thesis on colloids: micro particles with which you can form larger structures. Meester developed a method to make unusable structures usable.

Researchers at Leiden University and TU Delft have combined two techniques that are used to measure the structure of biomolecules, creating a method that is ten times more sensitive.

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

Gold nanoparticles give us a better understanding of enzymes and other molecules. Biswajit Pradhan, PhD candidate at the Leiden Institute of Physics, uses gold nanorods to study individual molecules that would be challenging to detect otherwise. Resulting knowledge can be applied to many research fields,…

Microneedles are a promising tool for the painless administration of vaccines through the skin. But, are these minuscule needles really effective? PhD student Pim Schipper of the Leiden Academic Centre for Drug Research investigated various factors of vaccination via the skin and discovered, among other…

The European Research Council (ERC) has awarded chemist Dr Alexander Kros a Starting Independent Researcher Grant of 1.4 million euro. He will be using the grant to study how molecules penetrate the natural barrier of a cell membrane. If his research is successful, it will in time bring about a revolution…

An international team of researchers, including Federico Calle-Vallejo of Leiden University’s Institute of Chemistry, have taken the atomic-scale design of catalysts to the next level. Their research contributes to the quest for a method to generate or store energy more efficiently. The report is published…

Martina Huber, Jacqueline Labra Munoz research Alzheimer's disease. They study ferritine, iron storage in the brain. An inbalance of iron could play a role in this form of dementia.

What if you could watch a CT scan live, instead of analysing the images afterwards? If it is up to the Leiden mathematician Jan-Willem Buurlage, that will soon be a reality. He is developing methods to make the algorithms behind 3D scans faster. Quite a challenge: ‘Just like mathematicians, computers…

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

PhD defence

PhD defence

PhD defence

PhD defence

The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

Lecture

Scientific research at the molecular level on a collection of medieval skeletons from Norton Priory in Cheshire, United Kingdom, could help rewrite history after revealing they were affected by an unusual ancient form of the bone disorder, Paget’s disease. Osteoarchaeologist Carla Burrell, attached…

Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column

The province of South Holland is to collaborate with industry, the three LDE universities Leiden Delft and Erasmus, and the University of Wageningen in a knowledge and innovation programme to speed up the transition to a circular economy. The programme, ACCEZ, is expected to generate new knowledge.

Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.

A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.

During Seeing Stars Leiden all the lights around Leiden Observatory will be switched off for an hour. The more lights that go out, the more stars we’ll be able to see. For the LUMC, this is the perfect moment to think about our biological clock, the topic researchers from the BioClock consortium are…

Some governments and companies are pursuing a more circular economy, but what is the best way to get there? An international group of industrial ecology researchers wrote a report that stresses the importance of including the scientific side into policies and practices. ‘We feel an obligation to support…

Why do we need fundamental science? For a lot of reasons, speakers showed at the Lustrum Symposium ‘Science Matters’. This symposium was held on 18 March 2016 to celebrate the 200th anniversary of the Faculty of Science.

Six researchers from Leiden University have been awarded NWO Open Competition funding.

Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.

From a white leather armchair, on which Barack Obama once sat, Dean Michiel Kreutzer opened the academic year. This time not with visitors, but completely corona-proof via a live stream. In a homely setting, Kreutzer spoke with several guests, including Covid-19 researcher Thomas Hankemeier and brand…

More than half of the Indonesian population lives in cities. What does this mean for public health? How sustainable are these megacities? This is the subject of the ‘Urban Transitions’ Summer Academy on West Java. This summer course is also the kick-off for a renewed interdisciplinary partnership…

Your local city park may be improving your health, according to a new paper led by Leiden environmental scientist Roy Remme. In Proceedings of the National Academy of Sciences Remme and his colleagues describe how access to nature increases people’s physical activity—and therefore overall health—in…

You should start working now, and the positive results will only be seen long after your term has expired. That is just about the worst thing you can say to politicians and policymakers. Yet that is exactly the message of two recent reports on sustainable resource use from the Centre for Environmental…

In 2021, the eleventh Conference of the International Society for Industrial Ecology will take place in Leiden. The Institute of Environmental Sciences Leiden (CML) has been elected to host the next biennial meeting at the latest conference of the Society in Beijing, China. ‘Industrial ecology can play…

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

A European consortium has provided a disruptive technological breakthrough to allow the discovery and characterization of novel enzymes for industrial biotechnology. The technology will open the way to more efficient industrial processes such as in the biofuel, animal feed and paper and pulp industr…