This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.

The aim of the Indonesian-Dutch Literature Collective (which is allied to the Society of Dutch Literature (MNL)) is to support research into the literature of and about the Dutch Indies, from the era of the Dutch East India Company to the present. Starting in 1986, the collective has published its own…

Leiden PhD student Peter Koymans has been declared ‘best mathematics PhD student’ by the Royal Dutch Mathematical Society (KWG). He received the prize at the Dutch Mathematical Congress (NMC) on 24 and 25 April. With his talk about his research into the Cohen-Lenstra conjecture, Koymans left eleven…

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.

The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…

This project intends to provide the required knowledgebase for the design of novel mild intervention protocols to prevent fungal food spoilage.

How has early development in R. ocellatus been modified as a result of its parasitic embryonic lifestyle?

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Visualization of biomolecules in living cells by tagging with gold nanoparticles.

Research how ‘custom’, ‘traditions’ and ‘heritages’ take on new meanings in the uplands of South and (mainland) Southeast Asia.

What are the functions of autophagy in the filamentous fungus Aspergillus niger?

Which microorganisms live near and inside plant roots? How do they contribute to plant health? Can microorganisms be employed in plant protection?

A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.

The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

Conference

Lecture

On 20 December 2013, the Netherlands Organisation for Scientific Research (NWO) announced that 37 teachers will be conducting doctoral research funded by a Doctoral Scholarship. Using this scholarship, teachers are enabled, in addition to their educational activities, to conduct research leading to…

Promotor: Prof.dr. G.J. Kroes

Leiden University Medical Center (LUMC) has spent the past five years coordinating an international study of genetic mutations and breast cancer risks. The results will make it easier to determine which genes increase the risk of breast cancer and to what extent. The researchers published their results…

PhD defence

Lecture

On Wednesday September 26th, theoretical physicist Sean Carroll will give an Ehrenfest colloquium. It is part of a lecture series that has been running since 1912 and was founded by physicist Paul Ehrenfest.

On November 6th PhDArts Co-Director Dr. Janneke Wesseling has given a keynote presentation, entitled “On Methodology”, at the Symposium Conversations on Artistic Research in Porto (PRT).

On November 21, theoretical physicist Juan Maldacena gives the Ehrenfest Colloquium. Maldacena is known worldwide as the inventor of AdS/CFT correspondence, which might be key to a theory of quantum gravity. Maldacena is winner of the prestigious Dirac Prize and the Breakthrough Prize in Fundamental…

Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).

To be eligible for Biology at Leiden University, you must meet the following admission requirements.

To be eligible for Biology and Education at Leiden University, you must meet the following admission requirements.

Fatemeh (Simin) Tabassi Mofrad has recently received a project grant (€ 25,000) from LUF/Gratama Foundation for her ideas in investigating sex-by-genotype interactions in brain functions. She has a multidisciplinary research perspective which enables her to look at research issues from different angles.…

The intestinal bacterium E. coli can adapt to changes in its surroundings. Leiden scientists have discovered how the H-NS protein makes this possible. This new knowledge can be an important starting point in combatting bacteria and diseases such as peritonitis. Publication 2 October in the journal e…

Physicists understand little about quantum matter, which is a building block of future quantum computers. Theorists have now discovered that black holes with ‘dreadlocks’ harbor a similarly exotic order pattern, which makes calculations on quantum matter easier. Publication in Physical Review Letter…

Ben Wielstra strives to unravel the evolution of balanced lethal systems. On 1 February he started his own lab at the Institute of Biology Leiden. Wielstra is one of five researchers at Leiden University who has been awarded an ERC Starting Grant in 2018 by the European Research Council. ERC Starting…

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

docARTES is a doctoral programme for performers and composers. It offers a unique environment for critical reflection on musical practice.

Scientist looked for the genetic footprint of fire use in our genes, but found that our prehistoric cousins - the Neanderthals - and even the great apes seem better at dealing with the toxins in smoke than modern humans.

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.

Publication by: Anouk Wezel, Sabine Welten, Wida Razawy, Max Lagraauw, Margreet de Vries, Eveline Goossens, Martin Boonstra, Jaap Hamming, Ekambar Kandimalla, Johan Kuiper, Paul Quax, Yaël Nossent and Ilze Bot. Annals of Surgery. 2015;262:841-848.

Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.

Single-celled organisms have stiffer DNA than multicellular lifeforms like humans and rice. Theoretical physicists managed to simulate the folding in full genomes for the first time to reach this conclusion. Publication in Biophysical Journal on February 7.

People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.