1,273 search results for “active smit master” in the Public website
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A community computational challenge to predict the activity of pairs of compounds
Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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comprehensive and predictive theory of catalysis based on simple structure-activity relations
Can we tailor catalysts at the atomic scale by means of high-school chemistry and geometry rules?
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education: design, implementation and evaluation of group learning activities
The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.
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Intersectional activism: Dutch-Turkish Muslim women 'talking back' to securitization and Islamophobia
This article investigates the efforts of influential Turkish Muslim civil society actors to amplify the voices of Muslim women in the Netherlands.
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S/N-functionalized NHC ligands: structures, redox properties and electrocatalytic activity
The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.
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The interpretation of physical activity wearable data and its relation with metabolic and brain health in older adults
Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…
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Far-Right Activism: A Comparative Analysis of the Motivating Factors Driving Men and Women to Engage in Far-Right Social Movement Activism in the
In the present-day United States, to what degree(s) are far-right men and women similar and/or dissimilar in their motivating factors for engaging in far-right social movement activism?
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Worm and stomach bacteria: our allies in the battle against allergic asthma
Parasitic worms and stomach bacteria suppress immune reactions such as allergic responses. Parasitologist Hermelijn Smits and lung specialist Christian Taube from the LUMC are trying to learn from these micro-organisms.
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Key publications
Key publications of the Aging and Immunity group
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Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and
Source: Mol Psychiatry (2015)
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining β-Exoglucosidases In Situ and In Vivo
A high-end label: Cyclophellitol aziridine-type activity-based probes allow for ultra-sensitive visualization of mammalian β-glucosidases (GBA1, GBA2, GBA3, and LPH) as well as several non-mammalian β-glucosidases (see picture). These probes offer new ways to study β-exoglucosidases, and configurational…
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Information activities
Do you want to know more about Cultural Anthropology and Development Sociology and what it is like to study in Leiden? Come to our online or on campus information events.
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Highly Efficient Activation of HCl Dissociation on Au(111) via Rotational Preexcitation
The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…
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The Future of the Dutch Colonial Past: Curating Heritage, Art and Activism
This book provides an overview of critical scholarly reflections on the history of Dutch slavery and colonization, as well as how this translates into critical cultural practices.
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European Law Master's Ambassadors
Do you have a question about the Europan Law LLM programme? Or would you like to know what it's like to study in Leiden as an international student? Our master's ambassadors are more than happy to answer all your questions. Feel free to send them an email!
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Teachers and students as partners in researching educational practice
How can collaborative participatory action research by student-teachers and their students enhance student participation, improve educational practices, and generate knowledge about these practices that can be used for improving teacher education as well?
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Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Education
Education and Organisation Development
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Organisation
The staff members of the Methodology & Statistics unit are members of various boards and committees.
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Roman-Catholic reactions to Protestant 'moderns' in the Netherlands, 1840-1870
Ineke Smit defended her thesis on 17 September 2019
- Meet our staff
- Meet our staff
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Positive assessment NVAO committee of new master’s degree programme Law & Society
Last week an audit committee from the Accreditation Organisation of the Netherlands and Flanders (NVAO) visited the Wijnhaven building at Campus The Hague to review the proposed new English-taught master’s degree programme ‘Law & Society: Governance and Global Development’.
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Graduation ceremony master's programme Cultural Anthropology and Development Sociology
Festival, Graduation Ceremony
- Publication highlights
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New Master: Master Cyber Security Engineering
In cooperation with Cyber Security Academie (CSA) and The Hague University of Applied Sciences the new Master Cyber Security Engineering is established and starts in September 2018.
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Leiden Alumni win NVER 2016 Awards for Master Theses
The Europa Instituut is honoured to announce that two Leiden alumni received awards for their master theses at the annual meeting of the Netherlands Association for European Law (NVER) in Utrecht.
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Sylvestre Bonnet
Science
bonnet@chem.leidenuniv.nl | +31 71 527 4260
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the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Mersenne primes and class field theory
Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit
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Culture: text and images in Japan
One of the ways of understanding another culture better is to examine what people experience when they read a text, or look at an image. Leiden experts have a lot of knowledge in this field, for example on culture in ancient Japan.
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Weak coupling between magnetically inequivalent spins: the deceptively simple, complicated spectrum of a 13C-labeled trimethyl amine
A deceptively simple, complicated paper
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Youth and safety
Policy studies and interventions in the field of Youth
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Over 700 visitors at the Leiden Humanities Master’s Day
Students from Londen, Amsterdam and Leiden visited presentations and talked to students, tutors and alumni to find out more about the Master’s Programmes Leiden University has to offer.
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The role of glomerular filtration and active tubular secretion in predicting renal clearance in children using population pharmacokinetic and
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)
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Leiden Alumna wins NVER 2017 Award for Master Thesis
The Europa Institute is honoured to announce that a Leiden alumna has received an award from the Nederlandse Vereniging voor Europees Recht (NVER) for her master thesis.
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People
Overview of the Leiden Asia staff per area or country.
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Predictions Regarding the Effects of the COVID-19 Pandemic on the Activities of Violent Non-State Actors
In this article, Yannick Veilleux-Lepage and Tommy van Steen, assistant professors at the Institute of Security and Global Affairs, discuss the degree of consensus within the field of terrorism studies regarding the impact of the COVID-19 pandemic on the activities of violent non-state actors.
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particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Menu of active working methods: enrichment through activation
A new step towards the implementation of the Kernvisie! We’re proud to present the menu of active working methods. We’d also like to give you some more information about active teaching and how this is implemented in the lecturer phase for the first year of the bachelor’s programme.
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LUF: Master Thesis Grant
Leiden students! Are you planning on writing a master thesis related to packaging and environment? Apply for a 4,000 euro grant! 💚🌿🙌
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Chemokine signaling in Tuberculosis and Salmonella infection
Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?