2,776 search results for “heart and vascular disease” in the Public website
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Stevin Prize winner Andrea Evers: 'This award is for the whole team'
Health psychologist Andrea Evers has won the Stevin Prize – alongside the Spinoza Prize, the highest scientific award in the Netherlands. Evers: 'It’s also a prize for our whole team and our many contacts within and outside the University.’
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Predictive pharmacology
The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.
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Host-Microbe Interactions in Microbial Sciences
Microbial Sciences' contribution to the Host-Microbe Interactions research theme is to investigate how beneficial or disease-causing microbes associate and interact with their host.
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Reading the Dental record
A dental anthropological approach to foodways, health and disease, and crafting in the pre-Columbian Caribbean.
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Master Projects
Master projects are available in
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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SDS-PAGE at the nanoscale: A nanorecorder for single molecule protein sequencing with graphene
Can we find new chemical and biological sensing routes on the edge and surface of graphene to improve the potential of graphene to act as a sensor?
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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High-Throughput Metabolomics
Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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The Mastermind approach to brain research
The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach. ‘In effect, it's like playing Mastermind.’ Inaugural lecture on 22 March.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Layers of dental tartar
Bacteria in the teeth tell us a lot about nutrition and disease in our ancestors. It also tells us more about the immune system. This provides clues for treating modern diseases and allergies. For a long time archaeologists were irritated by tartar on the teeth of excavated skulls. They thought that…
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Living and working in Leiden and The Hague - working at Leiden University
Leiden University has locations in both Leiden and The Hague.
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Neurodevelopmental risks in young children with an extra X or Y chromosome
This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.
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VICI grants for five Leiden researchers
Research organisation NWO has awarded a VICI grant to five Leiden researchers. In total, 32 leading researchers in the Netherlands have been awarded a VICI grant.
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Targeting Inter-Organ Cross-Talk in Cardiometabolic Diseases
PhD defence
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Political Religion Beyond Totalitarianism
The eleven innovative essays in this volume explore the notion that all forms of modern mass politics, including liberal democracies, need such a form of sacralization of politics to function.
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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ERC Consolidator Grants for four Leiden researchers
From fake news via WhatsApp to mini hearts from a 3D printer: four Leiden researchers have been awarded a Consolidator Grant by the European Research Council. These grants, of up to 2m euros, enable researchers to establish or expand their research team and continue to develop their career.
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5 Vidis for Leiden researchers
Of the 87 Vidi research subsidies awarded by NWO, five have been awarded to Leiden researchers. This represents almost 6 per cent of the successful applications.
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A quick call with Nadine Akkerman about the Annie Romein-Verschoor Lecture: ‘I feel a connection with Annie’
Each year on or around International Women’s Day, the university hosts the Annie Romein-Verschoor Lecture. You are welcome to attend − even if you wouldn't call yourself a feminist, says professor and organiser Nadine Akkerman. ‘You get the best discussions with a diverse audience.’
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Live long and healthy
Leiden University will be 444 years old this year and is still very much alive and kicking. But how can we humans grow old healthily? Hanno Pijl at LUMC is the grand master of lifestyle medicine. He explains how we can all benefit from a sensible - but still enjoyable - lifestyle.
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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NWO awards curiosity-driven research Ariane Briegel with grant
Professor of Ultrastructural Biology Ariane Briegel has received a grant in the NWO Open Competition Domain Science in the XS category. This grant emphatically encourages curiosity-driven and bold research with a maximum of 50,000 euros.
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Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
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Global Health, Innovation and Society (BSc Major of Liberal Arts and Sciences: Global Challenges)
Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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26 million for research into the impact of non-genetic factors on health
Who will be affected by certain chronic diseases, and who will not? For 30 percent that depends on heredity factors, whereas no less than seventy percent is explained by external factors. A Dutch research consortium receives 18 million euros from the prestigious Zwaartekrachtsubsidies to study these…
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Osteoarchaeologist Maia Casna receives the NVFA Incentive Prize: ‘I try to push osteology into the public eye as much as I can’
PhD candidate Maia Casna received an Incentive Prize from the Dutch Association for Physical Anthropology (NVFA). She was rewarded this honor for her innovative research into respiratory diseases and her talent for presenting her results to both academic and general audiences. ‘It feels really nice…
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Research
The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.
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Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
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Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
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Versatile SNP genotyping
The SNP genotyping line offers flexible genotyping for small and large projects at affordable price and high quality. The use as SNPs as molecular markers is very versatile and can be used for a wide variety of scientific questions ranging from paternity analysis, conservatuion genetis towards QTL…
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Growth and development of actinomycetes
We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.
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HURP: Helsinki Urban Rat Project
How humans and rats cohabit the cityscape and what consequences this has for both sides of the conflict?
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Unwiring beneficial functions and regulatory networks in the plant endosphere
How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?
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Quantitative Systems Pharmacology
This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).