1,487 search results for “global gene regulation” in the Public website
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ZF-HEALTH - Zebrafish Regulomics for Human Health
How can zebrafish research help understanding human diseases?
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Johan Christensen for the Global Blog about experts in global governance
Recently, Johan Christensen, Assistant Professor at the FGGA, contributed to the commentary series on technocracy and democracy in global governance that is organised by the Global Governance Centre and the Albert Hirschman Centre on Democracy.
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Another global environmental conference is far more successful than the UN Climate Conference
In Montreal, the 34th Meeting of Parties on the Montreal Protocol (MOP), dealing with ozone layer damage, just ended. This protocol is ratified by all countries in the world and is very successful. Shiming Yang, a university lecturer and member of the Leiden University Global Transformations and Government…
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Understanding plant transgenesis
How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?
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Half minor Global Health a great success!
The pandemic has challenged us to revisit the way we structure education and how to reach out to students remotely. It almost seems fitting that a course devoted to a topic so closely related to the context of the corona crisis, that of global health, would explore the possibilities of making the course…
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Lunch Seminar: Transformations in Global Climate Finance
On 8 April, Michael Sampson and Shiming Yang, from the new GTGC Seed Grant project 'Transformations in Global Climate Finance' presented on their research set-up and engaged in a discussion with the audience.
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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In Pursuit of Next-Generation Lipopeptide Antibiotics
Can new variants of daptomycin and the polymyxins be found?
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Solvent tolerance mechanisms in Pseudomonas putida
Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
- Leiden Institute of Chemistry
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CoSTREAM: Understanding Stroke and Alzheimer
The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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Chromatin organisation & dynamics
The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…
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Research Team Globalizing Palliative Care complete
The project officially started in September 2020, but with the enrolment of PhD students Hanum Atikasari and Shajeela Shawkat the research team of the ERC project 'Globalizing Palliative Care? A Multi-sited Ethnographic Study of Practices, Policies and Discourses of Care at the End of Life' is compl…
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engages the European robotics community in shaping the future of robot regulation
As part of the LIAISON Research Project, Eduard Fosch-Villaronga and Hadassah Drukarch organised a workshop at the European Robotics Forum (ERF 2021) to engage the broader community in the projects’ goal of liaising robot development and policymaking.
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2011 Leiden Centre for Global Heritage
A Centre for Global Heritage will be set up at Leiden University, that integrates the unique global breadth and quality of academic expertise at the University and the Leiden Museums with the global infrastructure of practical consultancy expertise built up over the past years by the Centre for International…
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GTGC Global Justice and Human Rights Seminar
On 28 October 2021, Matthew Hoye presented his paper during a seminar organized by the GTGC Global Justice and Human Rights group. His paper was about the Remittances and Global Justice: Paradoxes and Potentials.
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Global Governance Journal comes to Leiden
A team of researchers based at Leiden has taken over the editorship of the journal Global Governance: A Review of Multilateralism and International Organizations. For the first time, the journal will now be based outside the United States. The new Editor-in-Chief, Associate Professor Alanna O'Malley…
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Future Directions in Global Legitimacy Research
Jan Aart Scholte was lead organizer of a conference on ‘Future Directions in Global Legitimacy Research’, held in Stockholm on 21-22 June 2022. The gathering assembled 50 leading scholars on this subject to reflect on future research concerning the sources, processes, and consequences of legitimacy…
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Follow the Governance and Global Affairs Blog
Stay in touch with the recent developments at the faculty!
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Jelena Belic
Faculteit der Sociale Wetenschappen
j.belic@fsw.leidenuniv.nl | +31 70 800 3879
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Michael Sampson
Faculteit der Sociale Wetenschappen
m.d.sampson@fsw.leidenuniv.nl | +31 70 800 6617
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Xiaoyang Zhong
Science
x.zhong@cml.leidenuniv.nl | +31 71 527 5148
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Joris Larik
Faculty Governance and Global Affairs
j.e.larik@luc.leidenuniv.nl | +31 70 800 9503
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Yali Si
Science
y.si@cml.leidenuniv.nl | +31 71 527 2727
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Stephen Harris
Faculty of Humanities
s.e.harris@hum.leidenuniv.nl | +31 71 527 8983
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Bernhard Rieger
Faculty of Humanities
b.rieger@hum.leidenuniv.nl | +31 71 527 1290
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Jos Gommans
Faculty of Humanities
j.j.l.gommans@hum.leidenuniv.nl | +31 71 527 2167
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Riccardo Mancinelli
Science
r.mancinelli@cml.leidenuniv.nl | +31 71 527 2727
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Jonathan London
Faculty of Humanities
j.d.london@hum.leidenuniv.nl | +31 71 527 2732
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Karen Smith
Faculty of Humanities
k.smith@hum.leidenuniv.nl | +31 71 527 1737
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Madeleine Hosli
Faculty Governance and Global Affairs
m.o.hosli@fgga.leidenuniv.nl | +31 70 800 9581
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Matthew Hoye
Faculty Governance and Global Affairs
j.m.hoye@fgga.leidenuniv.nl | +31 70 800 9506
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Jue Wang
Faculty of Humanities
j.wang.18@hum.leidenuniv.nl | +31 71 527 7947
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Alyssa Akkerman
Faculteit der Sociale Wetenschappen
a.t.akkerman@fsw.leidenuniv.nl | +31 71 527 2727
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Kiri Paramore
Faculty of Humanities
k.n.paramore@hum.leidenuniv.nl | +31 71 527 2727
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Jiyan Qiao
Faculty of Humanities
j.qiao@hum.leidenuniv.nl | +31 71 527 2977
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Raoel Nanhekhan
Faculty Governance and Global Affairs
r.m.f.nanhekhan@fgga.leidenuniv.nl | 070 8009605
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Paul van Trigt
Faculty of Humanities
p.w.van.trigt@hum.leidenuniv.nl | 071 5271349
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Jan-Bart Gewald
Afrika-Studiecentrum
j.b.gewald@asc.leidenuniv.nl | +31 71 527 3372
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Joachim Koops
Faculty Governance and Global Affairs
j.a.koops@fgga.leidenuniv.nl | +31 70 800 9506
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Oliver Taherzadeh
Science
o.a.taherzadeh@cml.leidenuniv.nl | +31 71 527 2727
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Carolien Stolte
Faculty of Humanities
c.m.stolte@hum.leidenuniv.nl | +31 71 527 7308
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Citizenship, Migration & Global Transformation: an interdisciplinary research project
A research team of fifteen people – representing domains such as political economy, international relations, law, history and public administration - will work on the interdisciplinary programme Citizenship, Migration and Global Transformation. Leiden University has granted 3.5 million euro's to the…
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Kick off Honours Programme Tackling Global Challenges
During the honours programme’s start of the year event of September the 15th, Pierre van Eijl and Albert Pilot were invited to talk about their research on talent development in honours programmes and the honours laboratory for 21st century skills. The honours programme with a new name is ‘Tackling…