The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

Chemist Sander van Kasteren aims to accurately map how our immune system responds to vaccines, particularly those aimed at curing diseases like cancer and chronic viral infections. The goal is to use this knowledge to improve vaccine design. An ERC Consolidation Grant will provide him with the funding…

Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.

What is the nature and scope of violence? Who offends, and in what context? Who are the victims? And how can we design suitable intervention and prevention strategies? In this track, you will be familiarised with the many faces of violent offending, to provide the knowledge and tools to understand,…

Leiden University will be 444 years old this year and is still very much alive and kicking. But how can we humans grow old healthily? Hanno Pijl at LUMC is the grand master of lifestyle medicine. He explains how we can all benefit from a sensible - but still enjoyable - lifestyle.

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

In this research line, the role pharmacological agents and neurochemcial processes play in behavior and cognition is examined with a particular focus on pain, placebo and nocebo effects and intensive care treatments.

VODAN Africa started as a platform to enable access to critical data needed from Africa to fight the novel COVID-19. The initiative was inspired by the experience from the Liberia Ebola Virus outbreak in 2014: early detection requires contact tracing. Inclusion of the most vulnerable is critical to…

The Biomedical Sciences Master programme in Leiden will help to deepen and broaden your understanding of human health and disease. We provide you with a challenging and flexible programme in a personalized environment.

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

Description of Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT) (2004 - 2007)

Various Leiden researchers have been awarded a European grant to explore the commercial or societal potential of previous research.

A History of Dutch Corruption and Morality showcases 300 years of change, continuity, and diversity in the history of Dutch political corruption and public morality. It analyses a series of corruption scandals and shows how the following debates were connected to the big changes of that time: from the…

Online teaching has made it much easier for international students to join in our courses. The Leiden minor in Global Health, for instance. Students from Tanzania, Rwanda, Uganda and Malawi logged on and made a valuable contribution with their knowledge, about tropical diseases, for instance.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

This research investigates the impact of socioeconomic developments on the physical condition of medieval populations in Holland and Zeeland between AD 1000 and 1600 through the analysis of human skeletal remains from three archaeological sites.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…

Many dangerous diseases such as COVID-19, Ebola and Q fever have jumped from animals to humans. But it is not only because of these diseases that we should include animals in our health policy, but also because of their right to health.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.

Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…

Iranian molecular plant biologist Salma Balazadeh started her career in Germany. Now she sets up a research group in Leiden to study stress in plants to secure global food supply. Her outlook on women in science in the context of the International Day for Women and Girls in Science, 11 February.

Professor of rheumatology Annette van der Helm focuses her research on the earliest possible detection of inflammatory joint rheumatism to prevent symptoms from becoming chronic.

In case of serious illness, treatment in the Intensive Care Unit (IC) may be necessary. Intensive care treatments has improved over the years and more and more seriously ill patients are surviving admission to the ICU. This favorable development however has a downside since long-term consequences of…

This research project studies the distribution and impact of medieval malaria in the Netherlands.

With a starting grant of the European Research Council (ERC) for promising young researchers, Eiko Fried aims to develop a personalised early warning system, that will reliably forecast depression before it occurs. Fried (Clinical Psychology) talks about this WARN-D, promising to radically transform…

On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

Do you want to learn how to prevent child problems by optimising caregiving? Would you like to advise parents, professional caregivers and policy makers on caregiving-issues? In that case the master’s specialisation Parenting and Child Development is the ideal choice for you!

In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.

The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach. ‘In effect, it's like playing Mastermind.’ Inaugural lecture on 22 March.

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Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

The research master's specialisation Clinical and Health Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

PhD defence

PhD defence