779 search results for “target therapy” in the Public website
-
Grant Elise Mathilde Fund & LUF: Using virus to kill bacteria: design of innovative phage-antibiotic combination treatments to combat antimicrobial
Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.
-
LEF grant for Semiha Aydin to pilot social anxiety treatment
Semiha Aydin is one of the three first-generation researchers who received a grant from the Leiden Empowerment Fund to stimulate their scientific career.
-
Macrophages as drivers of an opportunistic infection
The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic pathogen that may have large implications for treatment strategies.
-
Covalent Inhibitors for the Proteome-wide Identification of New Druggable Targets for Antibiotics
Lecture
-
Medical Delta professor Marco van Vulpen: ‘I advocate the introduction of the share factor’
Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…
-
On barriers and bridges: autoimmune rheumatic diseases and the road to a cure
Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…
-
Small molecule prevents tumour cells from spreading
Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…
-
How brain disorder models are like the Night Watch
Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.
-
Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
-
Ten years ERC: Sylvestre Bonnet kills cancer with light
In 2013, Sylvestre Bonnet received an ERC Starting Grant to kill cancer with molecules that can be activated by light. Two postdocs and three PhD students later, the end approaches of his so far successful project.
-
MDMA and virtual reality as trauma treatment
Military veterans with posttraumatic stress disorder often have symptoms that are both chronic and complex. Professor by Special Appointment Eric Vermetten is looking for new ways to help them deal with these. One possible medicine: party drug MDMA.
-
How public money for science leads to new medicines
Public funding for fundamental research is essential for innovation and the development of new medicines. This is demonstrated by Professor Science Based Business Simcha Jong and his colleague Hsini Huang after studying US federal funding restrictions for stem cell research under President George W.…
-
About the programme
The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.
-
Reportage: training anxious children should help prevent disorders and depression
Many primary school children suffer from anxiety and their numbers are increasing. Psychologists from the Knowledge Center Anxiety & Stress (KAS) are developing and researching preventive training.
-
Are bacteriophages the new antibiotics?
Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could be used to treat one of the WHO bacterial strains of concern where new treatments are urgently…
-
The QSPainRelief consortium will improve the treatment of chronic pain
The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.
-
Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
-
CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mi
Publication by: Amanda Foks, Gijs van Puijvelde, Jolien Wolbert, Mara Kröner, Vanessa Frodermann, Thomas van der Heijden, Peter van Santbrink, Louis Boon, Ilze Bot and Johan Kuiper. Cardiovascular Research. 2016;111(3):252-261.
-
Sibel Bahtiri is one of the new Faces of Science: ‘I want to show how we’re finding alternatives to animal testing’
PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.
-
Royal honour for gynaecologist Dick Oepkes
LUMC professor and gynaecologist Dick Oepkes was made a Knight of the Order of the Netherlands Lion on 15 April. Mayor Henri Lenferink presented him with the medal at the end of on online symposium to mark Oepkes’ retirement.
-
I think that we can establish the best eye radiation chain in the world
Annually, approximately 60.000 people in the Netherlands undergo radiation therapy for cancer. Coen Rasch is dedicated to enhancing the precision of proton therapy.
-
RARE-NL: LUMC joins consortium to find treatments for rare diseases
RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.
-
Cell-based medicinal products: grant rejected, paper published
Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.
-
Professor Aartsma-Rus receives Ammodo Science Award
Professor Annemieke Aartsma-Rus from Leiden University Medical Centre (LUMC) has received the Ammodo Science Award for her research into the muscular disease Duchenne.
-
Podcast: Becoming a Clinical Psychologist
Soon you will have graduated, and then what? Maybe you've been dreaming of becoming a psychologist for years, but don't want to know where to start. In this episode, clinical psychologist and lecturer Sepideh Saadat tells you how to go about it.
-
Leiden University Medical Center
In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.
- Interdisciplinary Activity Grants
-
Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
PhD defence
-
image-based localization of lipid-based nanomedicines for the exploration of targeted drug delivery
PhD defence
-
Laura Heitman nominated for Prix Galien
Laura Heitman of the Leiden Academic Center for Drug Research (LACDR) has been nominated for the Prix Galien Research Award. This important pharmaceutical prize honors young, prominent researchers whose scientific research is of great importance for fundamental or clinical drug research.
-
LUBEC treatment centre: bridge between support and research
From anxiety disorders to an extremely unhealthy lifestyle. In the Leiden University Treatment and Expertise Centre (LUBEC) children and adults receive treatment that is in line with the newest scientific insights. The centre is also a training and research institution, so students and researchers are…
-
Binge-eating disorders in the Arab world and the Netherlands
Psychologist Bernou Melisse was shocked at the long waiting lists in the Netherlands for people with binge-eating disorders. The problem was not yet on the map in Saudi Arabia. She therefore decided to study how people suffering from binge eating can be helped better in their own region of the world.…
-
€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
-
Willem van der Does sheds new light on the at times pitch-black history of psychiatry
Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…
-
New Medical Delta professors mean boost for health and technology research
Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.
-
Eiko Fried in APS on Open Science
Although open science reforms have contributed to a more rigorous and robust psychological science, there is still much to improve. In Association for Psychological Science (APS), Eiko Fried points out two norms that open science reforms may have overlooked so far: communalism and universalism. 'Incorporating…
-
Zhiyi Yu - winner of LACDR Spring Symposium
Zhiyi Yu was elected as the winner of the annual PhD Competition at the LACDR Spring Symposium on June 17th 2014.
-
Tailored medicines
Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.
-
Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
-
Cancer patients want a doctor who shows empathy and doesn’t make vague promises
Patients with incurable cancer want their oncologist to be clear but to show empathy too. They find hard and vague communication harmful. These are the results of a study by psychologists from Leiden that has been published in the American journal Cancer.
-
Immune system important in atherosclerosis
The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defence 19 December.
-
New professor of Biotherapeutics Delivery at LACDR
Matthias Barz has been appointed full Professor of Biotherapeutics Delivery at the Leiden Academic Centre for Drug Research (LACDR).
-
Improving the treatment of newborn babies with life-threatening sepsis
Coen van Hasselt’s pharmacology group collaborated on a study recently published in the renowned Lancet Infectious Diseases. The international team mapped the antibiotic treatment of the life-threatening inflammatory reaction sepsis in newborn babies. They did this for low- and middle-income countries,…
-
300 million euros for new international stem cell consortium
The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…
-
Medicine development is hunting magic bullets
Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…
-
New insight into immune cell behaviour offers opportunities for cancer treatment
An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…
-
Cancer research focusing on quality of life
Cancer is one of the main causes of death in the Netherlands. Leiden researchers are working to improve the treatment of different types of cancer in order to increase the patient’s quality of life. A better understanding of how cancer develops will make it possible to deliver personalised and precise…
-
Targets for Improving Patient Outcomes after Major Gastrointestinal Cancer Surgery: The value of peri-operative care
PhD defence
-
Huge advances could be made in the treatment of patients with childhood trauma
There’s a lot that goes wrong in the treatment of patients with PTSD caused by childhood trauma. Endowed professor Maartje Schoorl wants to resolve this by bringing scientific research closer to the practice. Inaugural lecture on Friday 29 April.
-
Dick Stufkens Prize 2017 awarded to chemist Sven Askes
The Dick Stufkens Prize 2017 for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) is awarded to Dr Sven Askes. In his thesis