Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Source: Mediators Inflamm (2014)

Embracing the Provinces is a collection of essays focused on people and their daily lives living in the Roman provinces, c. 27 BC-AD 476. It offers an overview of current research on Roman provinces and frontiers, deconstructing some long-held preconceptions and providing refreshing insights into unexplored…

Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

On October 31st, Margarita Gulian succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Margarita on this great result.

The thesis wishes to examine the pathways of thought underlying the creative act of music making and the performance practice of complex music from the late twentieth and early twenty-first century.

The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…

Promotor: Prof.dr. S. Haring

The linguistic project constitutes the connection between the two other subprojects. It consists of two parts.

On the 17th of January, Sarah Von Grebmer Zu Wolfsthurn successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sarah on this achievement!

How do technologies of computer vision, which promise to replace humans in the understanding of images, work in practice in the field of security, and what are their ethical and political implications?

This article examines the consequences of stereotypical beliefs regarding gender, traits, and leadership styles for manager preferences.

This thesis investigates the connection between tonal realization and tone change (tone sandhi) in Wenzhou Chinese, and whether and how such a connection is conditioned by prosodic structure and focus marking.

A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

In the spirit of 'unity in diversity', our objective is to promote insight into and appreciation for the wonder that the same physical laws and mathematical concepts apply to the whole of nature, from the largest to the smallest energy and length scales. We strive for the application of abstract theoretical…

The principal aim of this research is to explore the confrontation between voice and electronics. These are often seen as being radically different from one another and many characteristics seem to be in opposition between them. However, they also have characteristics in common and they can influence…

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

The research in Biological- and Soft-Matter Physics specialisation consists of 120 European Credit Transfer System (EC) points and includes electives (60 EC) and two research projects (60 EC).

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

Information for prospective, current and international students

Master

The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…

The two-year master’s programme in Computer Science at Leiden University offers seven specialisations ranging from AI to Bioinformatics and Data Science. The programme combines excellent theoretical teaching with possibilities for applied work with industrial relevance.

On 9 November, Roosmarijn van Es defended the thesis 'The mind in the courtroom: on forensic mental health reports in judicial decision-making about guilt and sentencing in the Netherlands. The doctoral research was supervised by Jan de Keijser, Maarten Kunst and Janne van Doorn.

'Re-territorialising skills? Insights from ethnography on solidarity-economy food activism' is written by Cristina Grasenni and published in the Special Feature: Original Article Agriculture (re‐)territorialisation: Balancing the promotion of local products and international trade in Europe.

In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

A friendly chat is more complicated than you might think. As soon as the other person finishes talking, you already have an answer ready. But how do we know when it's time to change turns? University lecturer Johanneke Caspers has been awarded an NWO Open Competition grant to investigate the role of…

PhD defence

Lecture, This Time for Africa!

Lecture, Com(parative) Syn(tax) Series

Michel Orrit was awarded the Physica prize 2016 for his groundbreaking work on single molecule spectroscopy.

The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…

To what extent is sound a stressor to fish? And are behavioural and physiological phenotypes equally sensitive to disturbance by noise pollution?

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

Tracking early human behaviour through plant processing and -exploitation.

The ability to create objects and structures with our hands has been essential to human development. This ability is something modern society is at risk of losing. Leiden archaeologists gather knowledge about ancient processes of ‘making and creating’ over the centuries, knowledge that helps our current…

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

Life Sciences Artificial Intelligence Data Science

It is not man’s ingenuity, but rather materials that are the source of innovation and progress. This is what archaeologist Maikel Kuijpers concludes based on his research into craftsmanship and material processing in the Early Bronze Age.

Within the Graduate School you can conduct your PhD research in a wide range of subjects across the Social and Behavioural Sciences, with five distinct research areas offered by its Institutes.

Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.