2,095 search results for “war on drugs” in the Public website
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Personalized Medicine
Getting personal
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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The balkan war (1912-1913) and visions of the future in Ottoman Turkish literature
Engin Kiliç defended his thesis on 11 june 2015
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Spanish Heroes in the Low Countries. The Experience of War during the First Decade of the Dutch Revolt (1567-1577)
How do first-hand narratives of war of commanders in the front line relate to the official narrative of the Eighty Years’ War?
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The Reagan Administration, the Cold War, and the Transition to Democracy Promotion
Robert Pee, William Michael Schmidli (Eds.) This book posits that democracy promotion played a key role in the Reagan administration’s Cold War foreign policy.
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Protagonists of War: Spanish Army Commanders and the Revolt in the Low Countries
A new vision on the Revolt of the Low Countries through the eyes of Spanish commanders
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Japan’s Occupation of Java in the Second World War: A Transnational History
Japan's Occupation of Java in the Second World War draws upon written and oral Japanese, Indonesian, Dutch and English-language sources to narrate the Japanese occupation of Java as a transnational intersection between two complex Asian societies, placing this narrative in a larger wartime context of…
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Dutch Post-war Fiction Film through a Lens of Psychoanalysis
This week 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' by Peter Verstraten was published by Amsterdam University Press, the sequel to Humor and Irony in Dutch Post-war Fiction Film from 2016. Each chapter in his 482-page new study begins with a title of Fons Rademakers who made films…
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Reframing the Diplomat. Ernst van der Beugel and the Cold War Atlantic Community
In Reframing the Diplomat Albertine Bloemendal offers a unique window onto the unofficial dimension of Cold War transatlantic relations by analyzing the diplomatic role of the Dutch Atlanticist Ernst van der Beugel as a government official and as a private diplomat.
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The Fate of Freedom Elsewhere. Human Rights and U.S. Cold War Policy
This is the 2017 paperback release of William Michael Schmidli's The Fate of Freedom Elsewhere, which won the 2013 Foreign Affairs Magazine Best Book of the Year.
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Subjecthood?’ the Inclusion of Imperial Citizens in the Dutch Post-War Welfare State
Emily Wolff, PhD candidate at Leiden University, wrote a paper about the inclusion of imperial citizens in the Dutch post-war welfare state.
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The Great War Analogy and the Sino-American Security Dilemma: Foreboding or Fallacious?
Drawing on the analogical lessons of the Great War, this article uses applied history to analyze how the four parallels discerned can help us make sense of contemporary Sino-American rivalry
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Recovering and Analyzing Manuscript Archives Destroyed During World War II
Archives were a common target during the Second World War, and hundreds suffered damages. Among these archival losses, the losses to medieval manuscript collections stand out.
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Workers or Working Women? Comparing Labour Supply Policies in Post-War Europe
This paper written by Alexandre Afonso, Assistant Professor and Researcher at Leiden University, argues that gender norms and the political strength of the left were important structuring factors regarding why European countries choose migrant labour to expand their labour force in the decades that…
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Imperium: United States Foreign Policy and Human Rights in Post-Cold War Southeast Asia
Does foreign aid promote human rights?
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Drug development: how can we make it more efficient?
It takes years to develop new medicines, from the test tube to trials in humans. During the process it often happens that a drug that seems promising in the initial stage has to be dropped in a later phase. This costs time and money. Leiden University and the LUMC are working closely together to make…
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Military legitimacy during the Cold War: The Dutch army and its criticasters
Subproject of
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States, International Law, and the Monopolization of the Right to Wage War
States, we are told, have monopolized the legal right to wage war since the seventeenth century and this arrangement has provided some basic stability in international relations. But is this really true? This project challenges this classic account and opens the way for rethinking the contemporary laws…
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Rumours of Revolt: Civil War and the Emergence of a Transnational News Culture in France and the Netherlands, 1561–1598
This book explores the reception of foreign news during the late sixteenth-century civil wars in France and the Netherlands.
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Crossings: Indian activists and the Afro-Asian movement in the early Cold War era
Southern Crossings: Indian activists and the Afro-Asian movement in the early Cold War era
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Forged in the Great War : people, transport, and labour, the establishment of colonial rule in Zambia, 1890-1920
The territories that would make up what is today the Republic of Zambia officially became British in 1891. However, this did not equate to an on-the-ground presence of colonial authority capable of affecting the destiny and daily lives of people.
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Why are governments sharing intelligence on the Ukraine war with the public and what are the risks?
In this article, Thomas Maguire, assistant professor at the Institute of Governance and Global Affairs, examines the intelligence of the US, British and Ukrainian governments and NATO partners concerning Russia and its war against Ukraine. This article discusses how and why governments communicate intelligence…
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Digital warfare in the Sahel: popular networks of war and Cultural Violence
This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…
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the pharmacokinetics and pharmacodynamics of routinely used off-label drugs in premature neonates
Currently, more than 80% of drugs are used in an off-label manner in critically ill neonates.
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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Focus on kinetics for better drug development
Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…
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Infrastructure
An overview of our infrastructure at the SPP division:
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Rethinking drug discovery: Vidi grant for Laura Heitman
Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.
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War Heroes and War Criminals. The Spanish Commanders and their Actions during the First Decade of the Dutch Revolt in Narrative Sources from
How were Spanish commanders fighting in the Low Countries between 1567 and 1577 portrayed in Spanish and Dutch narrative sources during the Eighty Years War?
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Second World War victims commemorated in Hour of Remembrance
On 4 May, Leiden University remembered the victims of the Second World War from our university community. Alumni, students and present and former staff of the University came together for this Hour of Remembrance.
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Corinna Jentzsch, 'Here are 4 reasons why Mozambique isn’t a post-war success story' (blog)
Political scientist Corinna Jentzsch (Leiden University) explains why Mozambique is not (yet) a success story.
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Giulia Callegaro
Science
g.callegaro@lacdr.leidenuniv.nl | +31 71 527 6105
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Roos van der Haer
Faculteit der Sociale Wetenschappen
r.van.der.haer@fsw.leidenuniv.nl | +31 71 527 3886
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Bart Schuurman
Faculty Governance and Global Affairs
b.w.schuurman@fgga.leidenuniv.nl | +31 70 800 9347
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Frans Osinga
Faculty Governance and Global Affairs
f.p.b.osinga@fgga.leidenuniv.nl | +31 70 800 9506
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Finding unique drug structures with artificial intelligence and chemistry
In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.
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Student in war time
Jacques Waisvisz (98) is one of our oldest living alumni. As a Jewish student in the Second World War, he was forbidden from completing his studies. How does he look back at that time, and what was life like afterwards? ‘No one thought that the situation here would become so bad.’
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New technique offers chemists unprecedented control in drug research
Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…
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Mystical and Religious Concepts in the Persian Poetry of the Iran-Iraq War (1980-88)
The chief aim of this study is to explore how classical Persian poetry and the Persian mysticism that is interwoven with the poetry have been used in the new politics of the Islamic Republic of Iran, especially during the Iran-Iraq war.
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Drug Delivery to the Brain
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB
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PKPD and disease modelling in therapy development for amyotrophic lateral sclerosis (ALS)
We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.
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ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019)
On 1 June 2022, Bruno Braak defended his thesis entitled 'Overcoming ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019).' The doctoral research was supervised by Prof.dr. J.M. Otto, Dr.ir. C.I.M. Jacobs, and Dr. C. Leonardi…
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Capitalism, Migration, War and Nationalism in an Aegean Port Town: The Rise and Fall of a Belle Époque in the Ottoman county of Foçateyn
This dissertation describes the history of the Ottoman county of Foçateyn as a case study of the process of transition from the Ottoman Empire to nation states.
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Mayo: The Irish Revolution, 1912–23
The land question had a crucial formative influence on Mayo politics in the decades before the First World War and this book shows the part played by many prominent nationalist figures such as Davitt, O’Brien, Dillon and MacBride in shaping the political landscape in Mayo.
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How Leiden University reopened after the war
Students were able to continue their studies in September 1945 after the University had been closed for several years during the Second World War. This moment was celebrated for four days, with the traditional cortège, commemorative services and a party in the Botanical Garden. Queen Wilhelmina was…
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Images Of The Indonesian War Of Independence, 1945-1949/Beelden Van De Indonesische Onafhankelijkheidsoorlog, 1945-1949/Perang Kemerdekaan Indonesia
Four years of protracted negotiations and bitter warfare passed between the declaration of Indonesian independence on 17 August, 1945, and the official transfer of sovereignty on 27 December, 1949.
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‘Stolpersteine’ at the University Library to commemorate Leiden war victims
Two Stolpersteine (stumbling stones) have been placed in front of the University Library in memory of the Jewish Cosman family. At the time of the Second World War, they lived in one of the houses where the library is now located.